Biophysical Society 63rd Annual Meeting | Program Guide

967-Pos Board B69 IS THE SICKLE HEMOGLOBIN POLYMER STRUCTURE A FRUSTRATED SPIN- GLASS? Emily Harkness, Mark Davis, Marilyn F. Bishop, Kimberly C. Grasty, Patrick J. Loll, Frank A. Ferrone 968-Pos Board B70 THE ROLE OF CHARGE INTERACTIONS IN LIQUID-LIQUID PHASE TRANSI- TIONS. Iuliia A. Antifeeva, Alexander V. Fonin , Olesya G. Shpironok, Irina M. Kuznetsova, Konstantin K. Turoverov 969-Pos Board B71 MECHANISMS OF PROTEIN FIBRIL FORMATION IN AMYLOID BETA AND LY- SOZYME PROTEINS. Carlos M. Perez , Ghanim Ullah, Tatiana Miti, Martin Board B72 THE EFFECT OF SOLUTION PH ON THE STRUCTURE AND STABILITY OF LY- SOZYME AMYLOID FIBRILS. Anna I. Sulatskaya , Olga I. Povarova, Maksim I. Sulatsky, Irina M. Kuznetsova, Konstantin K. Turoverov 971-Pos Board B73 ON THE RELATIONSHIP BETWEEN AGGREGATION RATE AND MECHANI- CAL STABILITY IN PROTEIN AGGREGATION. Maksim Kouza , Andrzej Kolins- ki, Andrzej Kloczkowski, Irina Buhimschi 972-Pos Board B74 INTEGRATING REACTION-DIFFUSION DYNAMICS WITH A BIOPHYSICALLY DRIVEN DEFORMABLE MEMBRANE MODEL. Yiben Fu , Margaret Johnson 973-Pos Board B75 STUDY OF SELF-ASSEMBLY IN PROTEIN-PROTEIN INTERACTIONS IN UL- TRAFAST ENDOCYTOSIS. Yasaman Moghadamnia 974-Pos Board B76 USER-FRIENDLY SOFTWARE FOR SIMULATING NON-EQUILIBRIUM SELF- ASSEMBLY USING REACTION-DIFFUSION. Matthew J. Varga , Margaret E. Johnson Intrinsically Disordered Proteins (IDP) and Aggregates I (Boards B77 - B108) 975-Pos Board B77 THE INTRINSIC FOLDING MECHANISM AFFECTS THE COUPLED FOLDING- BINDING PROCESS OF UNFOLDED PROTEINS. Meng Gao, Zhengding Su, Yongqi Huang 976-Pos Board B78 RECOGNITION MECHANISM OF THE INTRINSICALLY DISORDERED DSRNA BINDING DOMAIN DCL1-A WITH ITS SUBSTRATE FROMMOLECULAR DYNAMICS SIMULATIONS. Yuwen Chen , Meng Gao, Yongqi Huang 977-Pos Board B79 MECHANISM OF COUPLED FOLDING OF DISORDERED COLICIN E3 RRNASE DOMAIN UPON BINDING WITH IM3. Xingyu Chen , Yongqi Huang, Zheng- ding Su, Meng Gao 978-Pos Board B80 THE RATIONAL DISCOVERY AND DESIGN OF DISORDERED PROTEIN LIGANDS. David W. Baggett , Abhinav Nath 979-Pos Board B81 TRAVEL AWARDEE POLYMER THEORY FOR SEQUENCE-SPECIFIC PHASE SEPARATION BEHAV- IORS OF CHARGED INTRINSICALLY DISORDERED PROTEINS. Yi-Hsuan Lin , Julie D. Forman-Kay, Hue Sun Chan Muschol 970-Pos

954-Pos Board B56 NATIVE QUANTITATIVE DETERMINATION OF ANTIBODY-DRUG CONJU- GATE AFFINITY AND STABILITY. Colette Quinn , Shawn Owen, Keith Arlotta 955-Pos Board B57 TRAVEL AWARDEE USING COMPUTATIONAL MODELING TO UNDERSTAND THE BINDING MECHANISM OF DESIGNED CYCLIC Β-HAIRPIN TO MDM2. Yunhui Ge , Vincent Voelz 956-Pos Board B58 SINGLE-MOLECULE FORCE SPECTROSCOPY SHOWS THAT THE ANTI-PRION COMPOUND PENTOSAN POLYSULFATE BINDS HETEROGENEOUSLY TO FOLDED AND UNFOLDED PRION PROTEIN. Rafayel Petrosyan , Patra Shub- hadeep, Negar Rezajooei, Craig Garen, Michael T. Woodside 957-Pos Board B59 SITE-SPECIFIC CHARACTERIZATION OF INTERMEDIATES IN FOLDING-TET- RAMERIZATION OF MELITTIN BY THE RAPID MIX/FREEZE METHOD AND MAGIC ANGLE SPINNING DYNAMIC NUCLEAR POLARIZATION (MAS-DNP) NMR AT LOW TEMPERATURE (25K).  Jaekyun Jeon , Kent Thurber, Wai- Ming Yau, Robert Tycko 958-Pos Board B60 RADIOLIGAND THERMOSTABILITY ASSESSMENT OF AGONIST-BOUND HU- MAN TYPE 2 CANNABINOID RECEPTOR. Ryan L. Beckner , Klaus Gawrisch, Alexei Yeliseev Protein Assemblies II (Boards B61 - B76) 959-Pos Board B61 TOWARDS UNDERSTANDING AMYLOID FORMATION MECHANISM OF BETA2-MICROGLOBULIN INDUCED BY COPPER IONS. Chungwen Liang 960-Pos Board B62 STUDYING MULTI-PROTEIN INTERACTIONS BY FLUORESCENCE DETECTED SEDIMENTATION VELOCITY COMBINING HYDRODYNAMIC SEPARATION OF COMPLEXES WITH FLUORESCENCE QUENCHING ANALYSIS. Huaying Zhao , Siddhartha A. Datta, Sung Kim, Sumit K. Chaturvedi, Alan Rein, Peter Schuck 961-Pos Board B63 NON-CLASSICAL NUCLEATION OF TUMOR SUPPRESSOR P53 FIBRILS HOSTED BY MESOSCOPIC PROTEIN-RICH CLUSTERS. Peter G. Vekilov 962-Pos Board B64 CORRELATING AMINO ACID SEQUENCE AND SOLVATION TO DISORDERED PROTEIN COLLAPSE TRANSITIONS AND PHASE SEPARATION. Erik W. Martin , Alex S. Holehouse, Ivan Peran, Anne Bremer, Rohit V. Pappu, Tanja Mittag 963-Pos Board B65 MULTI-STEP 2D PROTEIN CRYSTALLIZATION VIA STRUCTURAL CHANGES WITHIN AN ORDERED LATTICE.  Jonathan Herrmann , Colin J. Comerci, Fatemeh Jabbarpour, Lucy Shapiro, William E. Moerner, Soichi Wakatsuki 964-Pos Board B66 MODELING THE ASSEMBLY ORDER OF MULTIMERIC HETEROPROTEIN COMPLEXES. Lenna Peterson, Yoichiro Togawa, Juan Esquivel-Rodriguez, Genki Terashi, Charles Christoffer, Amitava Roy, Woong-Hee Shin, Daisuke Kihara 965-Pos Board B67 VARIABLE BINDING OF THIOFLAVIN T TO AMYLOID FIBRILS. Hiroaki Komatsu , Claire Meurice, Paul H. Axelsen 966-Pos Board B68 P-NITROPHENYLALANINE AS A NOVEL PROBE OF HYDROGEN BONDING IN PEPTIDE HYDROGELS AND PROTEINS. Nicholas R. John , Casey H. Lond- ergan, Karin Akerfeldt, Eliana V. von Krusenstiern

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