Biophysical Society 63rd Annual Meeting | Program Guide

Protein-Lipid Interactions: Channels (Boards B190 - B211)

1102-Pos Board B204 EFFECTS OF LIPID AND DETERGENT ENVIRONMENTS ON CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) FUNCTION AND STRUCTURE. Kerry M. Strickland , Brandon B. Stauffer, Yusuf M. Uddin, Barry R. Imhoff, Ingeborg Schmidt-Krey, Nael A. McCarty 1103-Pos Board B205 ALLOSTERIC MODULATION OF CA 2+ -ACTIVATED CL - CHANNLES TMEM16A BY PIP 2 AND CAMKII. Woori Ko , Seung-Ryoung Jung, Cheon-Gyu Park, Joo Hyun Nam, Bertil Hille, Byung C. Suh 1104-Pos Board B206 TRAVEL AWARDEE PIP 2 POTENTIATES THE CA 2+ -ACTIVATED CL - CHANNEL TMEM16A IN XENOPUS LAEVIS OOCYTES. Maiwase Tembo , Rachel E. Bainbridge, Anne Board B207 DETERMINING THE MECHANISM OF SMASE-MEDIATED INHIBITION OF CFTR CURRENT IN PRIMARY BRONCHIAL EPITHELIAL CELLS. Kirsten A. Cottrill , Brandon B. Stauffer, Nael A. McCarty 1106-Pos Board B208 TRAVEL AWARDEE IMPLICATION OF CHOLESTEROL IN REGULATING THE MEMBRANE-INTER- ACTION MECHANISM OF VIBRIO CHOLERAE CYTOLYSIN, A BETA-BARREL PORE-FORMING TOXIN. Reema Kathuria , Kausik Chattopadhyay 1107-Pos Board B209 DIFFERENTIAL STATE-DEPENDENT CROSSLINKING OF AZI-CHOLESTEROL WITH HUMAN A1 GLYCINE RECEPTOR USING MASS SPECTROM- ETRY. Nicholas A. Ferraro , Michael Cascio 1108-Pos Board B210 HIGH CHOLESTEROL DIET UP-REGULATES ATRIAL AND NEURONAL GIRK CHANNEL ACTIVITY. Anna N. Bukiya, Avia Rosenhouse-Dantsker 1109-Pos Board B211 PHOSPHOLIPID SCRAMBLING ACTIVITY BY TMEM16E/ANO5: OPPOSITE EFFECTS OF MUTATIONS CAUSING BONE DYSPLASIA AND MUSCULAR DYSTROPHY. Eleonora Di Zanni, Antonella Gradogna, Cristiana Picco, Joachim Scholz-Starke, Anna Boccaccio Membrane Structure II (Boards B212 - B232) 1110-Pos Board B212 TRAVEL AWARDEE SINGLE-LIPID SORTING AND DYNAMICS AT MEMBRANE CURVATURE SITES: THE EFFECTS OF FLUORESCENCE LABELING, COMPOSITION, PHASE, AND TEMPERATURE. Xinxin Woodward , Christopher V. Kelly 1111-Pos Board B213 PREDICTING SPECTRAL PROPERTIES OF POLARITY SENSITIVE DYES WITH QM/MM SIMULATION. Swapnil Baral , Lars Gundlach, Bjorn Baumeier, Edward R. Lyman 1112-Pos Board B214 MODELING THE INTERPLAY BETWEEN CURVATURE-INDUCING PROTEINS AND MEMBRANE GEOMETRY IN ORGANELLE STRUCTURES: CATENOID- LIKE NECKS AND HELICOIDAL RAMPS. Morgan Chabanon , Padmini Rangamani 1113-Pos Board B215 MECHANISTIC STUDIES OF MEMBRANE REMODELING IN RECEPTOR MEDIATED ENDOCYTOSIS. Samsuzzoha Mondal , Sankalp Shukla, Tobias Board B216 DRIVING SPONTANEOUS MEMBRANE CURVATURE BY TUNING CARDIO- LIPIN CONCENTRATION AND SPATIAL DISTRIBUTION IN MODEL MITO- CHONDRIAL MEMBRANES. Moeen Meigooni , Emad Tajkhorshid E. Carlson 1105-Pos Baumgart 1114-Pos

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1088-Pos Board B190 STRUCTURE-BASED ESTIMATE OF CONNEXIN 26 CONDUCTANCE. Nathan H. Zimmerberg , Satyan Sharma, Manfred Lindau 1089-Pos Board B191 INTERFACIAL EFFECTS OF ION CHANNELS IN LIPID MEMBRANES: MEAN- FIELD COMPUTATION FROM 3D ATOMIC STRUCTURES VERSUS ANALYTI- CAL ESTIMATES. Marcel Aguilella-Arzo, Antonio Alcaraz, Maria Lidon Lopez-Peris, Maria Queralt-Martin, Vicente M. Aguilella 1090-Pos Board B192 PROBING THE MECHANOSENSING FEATURES OF MAMMALIAN PIEZO CHANNELS AND PLANT OSCA CHANNELS VIA MOLECULAR DYNAMICS SIMULATIONS. Che Chun (Alex) Tsui , Kei Saotome, Sebastian Jojoa Cruz, Andrew B. Ward, Mark S. P. Sansom 1091-Pos Board B193 DRUG REGULATION OF ION CHANNEL FUNCTION INVOLVES BOTH DIRECT AND BILAYER-MEDIATED MECHANISMS. Radda Rusinova , Olaf Andersen 1092-Pos Board B194 PREDICTING THE PROMISCUOUS EFFECT OF AMPHIPATHIC DRUGS ON GRAMICIDIN CHANNEL STABILITY WITH SIMULATIONS AND EXPERI- MENTS. Delin Sun Sun 1093-Pos Board B195 PROTEIN-LIPID INTERFACES DRIVE DKTX-MEDIATED TRPV1 CHANNEL ACTIVATION. Debayan Sarkar , Yashaswi Singh, Jeet Kalia 1094-Pos Board B196 EFFECTS OF MEMBRANE PROTEIN NACHRS ON PHASE SEPARATED MODEL MEMBRANES.  Jigesh Patel 1095-Pos Board B197 BOUNDARY LIPIDS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR IN QUASI-NATIVE MEMBRANES. LiamM. Sharp , Reza Salari, Grace Bran- nigan 1096-Pos Board B198 EFFECT OF LATE ENDOSOMAL DOBMP LIPID AND TRADITIONAL MODEL LIPIDS OF ELECTROPHYSIOLOGY ON THE ANTHRAX TOXIN CHANNEL ACTIVITY. Nnanya Kalu, Yoav Atsmon-Raz, Sanaz Momben Abolfath, Laura Lucas, Clare Kenney, Stephen H Leppla, D. Peter Tieleman, Ekaterina M. Nestorovich 1097-Pos Board B199 NOISE PROPERTIES OF ION CHANNELS FORMED BY PESTIVIRUS VIROPO- RIN P7. Antonio Alcaraz , Vicente M. Aguilella, Eneko Largo, Jose L. Nieva 1098-Pos Board B200 REGULATION OF KCSA BY ANIONIC PHOSPHOLIPIDS. Carmen Domene , Victoria Oakes, Simone Furini 1099-Pos Board B201 ELUCIDATING CONFORMATIONAL CHANGES UNDERLYING THE CONVER- SION OF TMEM16A MUTANTS FROM ANION CHANNELS TO SCRAMBLA- SES. Archit K. Vasan , Tao Jiang, H Criss Hartzell, Emad Tajkhorshid 1100-Pos Board B202 INDUCING CHEMICAL CONCENTRATION GRADIENTS TO INVESTIGATE GAS PERMEABILITY OF RH-PROTEIN CONTAINING MEMBRANES. Eric Shinn , Emad Tajkhorshid 1101-Pos Board B203 ION TRANSPORT THROUGH LARGE-DIAMETER DNA ORIGAMI NANOTUBE CHANNELS ACROSS SYNTHETIC MEMBRANES. Naresh N. Dhanasekar , Rebecca B. Schulman

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