Biophysical Society 63rd Annual Meeting | Program Guide

Suchi M.D.C. Perera , University of Arizona, United States 268-Pos, B43 STRUCTURAL FLUCTUATIONS IN RHODOPSIN ACTIVATION REVEALED BY NEUTRON SCATTERING. Nihit Pokhrel , University of Washington, United States 713-Pos, B488 USING COMMITTOR AND ITS DISTRIBUTION TO ASSESS THE CONVERGENCE OF FREE ENERGY CALCULATIONS. Elias M. Puchner , University of Minnesota, United States 677-Pos, B452 QUANTITATIVE AND MOTION-CORRECTED SUPER-RESOLUTION IMAGING OF ENDOSOME DYNAMICS IN LIVING CELLS. Vatsal Purohit , Purdue University, United States 88-Plat TIME-RESOLVED CRYSTALLOGRAPHY MEASUREMENTS ELUCIDATING THE MECHANISM OF BACTERIAL HMG-COA REDUCTASE. Vani S. Ravichandran , University of Michigan, United States 148-Plat PROTEIN KINASE C-MEDIATED CARDIAC TROPONIN I S43/45 PHOSPHORYLATION CAUSES CONTRACTILE DYSFUNCTION IN HUMAN HEART FAILURE AND IN RODENTS. Erika Riederer , Oregon Health and Science University, United States 251-Pos, B26 INVESTIGATION OF EXTRACELLULAR GATE MOVEMENT IN A GLUTAMATE HOMOLOGUE. Nirakar Sahoo , University of Texas Rio Grande Valley, United States 82-Plat MODULATION OF KV10.1 POTASSIUM CHANNEL FUNCTION BY INTRACELLULAR HEME. Premila P. Samuel Mohan Dass , Rutgers University, United States 322-Pos, B97 RESOLVING THE TRANSITION STATES OF HUMAN HEMOGLOBIN ASSEMBLY THROUGH A COMBINATION OF SPECTROSCOPIC STUDIES AND ALL-ATOMMOLECULAR DYNAMICS SIMULATIONS. Nicolae Sapoval , University of Chicago, United States 238-Pos, B13 A NEW OPEN STRUCTURE OF THE INSULIN DEGRADING ENZYME PROVIDES INSIGHTS INTO THE CONFORMATIONAL TRANSITION OF THE MOLECULE. Nicoletta Savalli , University of California, Los Angeles, United States 551-Pos, B326 A MUTATION LINKED TO MALIGNANT HYPERTHERMIA IN THE SKELETAL CAV1.1 CHANNEL STABILIZES THE RESTING STATE OF VOLTAGE SENSOR I AND IMPAIRS CHANNEL ACTIVATION. Yiseul Shin , Florida State University, United States 289-Pos, B64 CHARACTERIZATION OF THE EXTRA-MEMBRANE DOMAINS OF CRGA IN LIPID BILAYERS USING SOLID STATE NMR. Ashley Simpson , Bay Path University, United States 324-Pos, B99 SGEF GEF ACTIVITY AND ITS REGULATION BY SCRIBBLE AND DLG1.

Chantelle L. Leveille , University of Washington, United States 396-Pos, B171 THE ROLE OF ERGOSTEROL IN PHASE SEPARATION OF YEAST VACUOLE MEMBRANES. Ao Li , Binghamton University – State University of New York, United States 105-Plat CHARACTERISTIC CONFORMATIONS OF PSEUDOMONAS QUINOLONE SIGNAL INTERACTING WITH BACTERIAL OUTER MEMBRANE. Worawan B. Limpitikul , Johns Hopkins University, United States 553-Pos, B328 PROBING L-TYPE CHANNEL CALCIUM-DEPENDENT INACTIVATION -- A BILOBAL MODEL OF CALMODULATION. Chris Lindsay , University of Oxford, United Kingdom 210-Plat MODELLING THE ATP BINDING SITE OF RYR2 TO RATIONALISE LIGAND- INDUCED GATING BEHAVIOUR. Anupa Majumdar , Indian Institute of Science Education and Research Mohali 139-Plat PROXIMITY RULERS IN AMYLOIDS AND LIQUID DROPLETS OF INTRINSICALLY DISORDERED PROTEINS. Deniz Meneksedag-Erol , University of Toronto Mississauga, Canada 74-Plat UNCOVERING THE MOLECULAR BASIS FOR THE CLINICAL N642H MUTATION IN STAT5B USING ATOMISTIC MOLECULAR SIMULATIONS. Hamed Meshkin , Purdue University, United States 231-Pos, B6 ATOMIC SIMULATIONS OF TRP-CAGE FOLDING BY UMBRELLA SAMPLING USING Q FUNCTION AS REACTION COORDINATE. Louisa Mezache , Ohio State University, United States 159-Plat VEGF-INDUCED VASCULAR LEAK PROMOTES ATRIAL FIBRILLATION BY DISRUPTING INTERCALATED DISC NANODOMAINS. Alexander E. Mosier , Rensselaer Polytechnic Institute, United States 321-Pos, B96 UNVEILING THE IMPACT OF THE NEGATIVE ARM OF THE CIRCADIAN CLOCK ON OUTPUT IN NEUROSPORA CRASSA. Buyan Pan , University of Pennsylvania, United States 325-Pos, B100 INVESTIGATING THE EFFECT OF ALPHA-SYNUCLEIN POST- TRANSLATIONAL MODIFICATIONS ON SYNAPTIC VESICLE TRAFFICKING. Andrea Papale , SISSA, Italy 349-Pos, B124 MICRORHEOLOGY OF INTERPHASE NUCLEI: A COMPUTER SIMULATION STUDY. Nabina Paudyal , University of Texas Health Science Center at Houston, United States 527-Pos, B302 STUDY OF A HETEROMERIC KAINATE RECEPTOR GLUK2/K5 BY PROBING SINGLE-MOLECULE FRET.

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