Biophysical Society 65th Annual Meeting Program Guide

1661-Pos B oard B263 DECIPHERING THE FUNCTION AND THE REGULATION OF PLASMODIUM FALCIPARUM MYOSIN A. Julien Robert-Paganin , Dihia Moussaoui, James P. Robblee, Daniel Auguin, Thomas C.A. Blake, Elena Krementsova, Jake Baum, Kathleen M. Trybus, Anne Houdusse 1662-Pos B oard B264 CONFORMATIONAL DISTRIBUTIONS OF ISOLATED MYOSIN MOTOR DOMAINS ENCODE THEIR MECHOCHEMICAL PROPERTIES. Gregory B oard B265 REGULATORY LIGHT CHAINS FINE-TUNE SKELETAL MUSCLE MYOSIN-II FUNCTION. Arnab Nayak, Tianbang Wang, Peter Franz, Walter Steffen, Igor Chizhov, Georgios Tsiavaliaris, Mamta Amrute 1664-Pos B oard B266 SWITCH I AND SWITCH II MUTANTS DIFFERENTIALLY IMPACT THE RECOVERY STROKE IN MYOSIN V. Laura K. Gunther, Rohini Desetty, Christopher M. Yengo 1665-Pos B oard B267 NEAR-ATOMIC STRUCTURE OF THE 10S FORM OF MYOSIN II: IMPLICA- TIONS FOR INHIBITION, ACTIVATION AND DISEASE. Prince Tiwari , Shixin Yang, Kyounghwan Lee, Osamu Sato, Mitsuo Ikebe, Raul Padron, Roger Craig 1666-Pos B oard B268 UNDERSTANDING HOWMUTATIONS IN NON-MUSCLE MYOSIN 2A DRIVE HUMAN DISEASE. David E. Casas-Mao Cytoskeletal Assemblies and Dynamics (Boards B269 - B280) 1667-Pos B oard B269 THE MITOTIC CROSSLINKING PROTEIN PRC1 ACTS LIKE A MECHANICAL DASHPOT TO RESIST MICROTUBULE SLIDING. Ignas R. Gaska, Mason E. Armstrong, April C. Alfieri, Scott T. Forth 1668-Pos B oard B270 COFILIN PROTECTS CONTRACTILE RINGS FROM BRIDGING INSTABILI- TIES. Zachary A. McDargh, Hongkang Zhu , Ben O’Shaughnessy 1669-Pos B oard B271 WRITHING OF CYTOKINETIC CONTRACTILE RINGS REVEALS THAT THE CONTRACTILE RING IS AN ELASTOPOROUS CABLE. Sathish Thiyagarajan , Dong An, Roberto Alonso-Matilla, Shuyuan Wang, Ting Gang Chew, Mohan Balasubramanian, Ben O’Shaughnessy 1670-Pos B oard B272 FUNCTIONAL OPTIMALITY OF THE HIGHLY CONSERVED ARP2/3MEDIATED 70° BRANCHING ANGLE. Rikki M. Garner , Julie A. Theriot 1671-Pos B oard B273 STRUCTURE AND FUNCTION OFABNORMAL SPINDLE-LIKE, MICROTU- BULE ASSOCIATED PROTEIN (ASPM). Marcus Holt , David E. Casas-Mao, Jacqueline Bond, Michelle Peckham 1672-Pos B oard B274 FUNCTIONAL DIFFERENCES BETWEEN Β- AND Γ-ACTIN: FROM TRANSLA- TION DYNAMICS TO AMINO ACID CHANGES. Pavan Vedula , Satoshi Ku- rosaka, Dawei Dong, Brittany MacTaggart, Qin Ni, Yi Jiang, Anna Kashina 1673-Pos B oard B275 QUANTITATIVE ANALYSIS OF ACTIN CYTOSKELETON’S MORPHOLOGI- CAL CHANGES DURING EMT IN LUNG CANCER AND PRE-CANCER CELL LINES. Arkaprabha Basu , Manash K. Paul, Mitchel Alioscha-Perez, Anna Grosberg, Hichem Sahli, Steven Dubinett, Shimon Weiss Bowman 1663-Pos

1674-Pos B oard B276 COLLECTIVE EFFECTS OF XMAP215, EB1, CLASP2, AND MCAK LEAD TO ROBUST MICROTUBULE TREADMILLING. Goker Arpag , Elizabeth J. Lawrence, Veronica J. Farmer, Sarah L. Hall, Marija Zanic 1675-Pos B oard B277 UNDERSTANDING THE MECHANISMS THAT GIVE RISE TO THE MAMMA- LIAN SPINDLE’S RESPONSE TO FORCE USING THEORY AND MICRONEE- DLE MANIPULATION. Vahe Galstyan , Pooja Suresh, Sophie Dumont, Rob Phillips 1676-Pos B oard B278 CYTOPLASM BIOPHYSICAL PROPERTIES LIMIT CYTOSKELETON DYNAM- ICS IN VIVO. Arthur T. Molines , Joel Lemiere, Claire H. Edrington, Chieh- Ting Hsu, Ida E. Steinmark, Klaus Suhling, Gohta Goshima, Liam J. Holt, Gary Brouhard, Fred Chang 1677-Pos B oard B279 TENSION-DEPENDENT MYOSIN DYNAMICS ON CONTRACTILE ACTOMY- OSIN STRUCTURES. Wen-hung Chou , David Kovar, Margaret L. Gardel 1678-Pos B oard B280 OPPOSING MOTORS PROVIDE MECHANICAL AND FUNCTIONAL ROBUSTNESS IN THE MAMMALIAN SPINDLE. Lila Neahring , Sophie Dumont Mitochondria in Cell Life and Death (Boards B281 - B294) 1679-Pos B oard B281 ON THE NATURE OF THE MITOCHONDRIAL PERMEABILITY TRANSI- TION. Carmen A. Mannella , Liron Boyman, Andrew Coleman, Christo- pher W. Ward, W. Jonathan Lederer 1680-Pos B oard B282 CONSEQUENCES OF INNER MEMBRANE FOLDING ON MITOCHONDRIAL ATP OUTPUT. Carmen A. Mannella , Nasrin Afzal, W. Jonathan Lederer, Mohsin S. Jafri 1681-Pos B oard B283 ROLE OF VDAC ISOFORMS IN ALPHA-SYNUCLEIN ENTRY INTO MITO- CHONDRIA. Megha Rajendran , Marie-Paule Strub, Sergey M. Bezrukov, Tatiana K. Rostovtseva 1682-Pos B oard B284 NME4 LOSS-OF-FUNCTION ALTERS MITOCHONDRIA, TRIGGERS RETRO- GRADE SIGNALING AND LEADS TO CELLULAR REPROGRAMMING. Uwe Schlattner , Frédéric Lamarche, Olivier De Wever, Cécile Cottet-Rousselle, Isabelle Hininger-Favier, Malgorzata Tokarska-Schlattner, Eric Fontaine, Morgane Le Gall, Gilhem Clary, Cedric Broussard, Philippe Chafey, Marie- Lise Lacombe, Mathieu Boissan 1683-Pos B oard B285 MITOCHONDRIAL CA 2+ UPTAKE IN OPA1 -/- CELLS IS UPREGULATED THROUGH FUNCTIONAL ER-MITOCHONDRIA COUPLING. Benjamín Cartes-Saavedra , Patrick Yu-Wai-Man, Gyorgy Hajnoczky, Verónica Eisner 1684-Pos B oard B286 PROHIBITIN OVEREXPRESSION PROMOTES OPA1 CLEAVAGE, REDUCES ROS AND IMPROVES RESPIRATION POST HYPOXIA. Wenzhuo Ma , Scar- lett M. Huck, Shanna Hamilton, Radmila Terentyeva, Dmitry Terentyev, Richard T. Clements 1685-Pos B oard B287 THE IMPACT OF MOLECULAR HYDROGEN ON MITOCHONDRIAL ROS AND APOPTOSIS IN COLORECTAL CANCER CELLS. Yi-Hsuan Tsai , Megha Jhunjhunwala, Tsan-Yao Chen, Chi-Shuo Chen

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