Biophysical Society 65th Annual Meeting Program Guide

General Protein-Lipid Interactions (Boards LB22 - LB30)

L1924-Pos Board LB33 SUBSTRATE STIFFNESS MODULATES INTEGRIN BETA-1 RECRUITMENT AT CELL-MATRIX ADHESIONS IN AGED VASCULAR SMOOTH MUSCLE CELLS. Krishna Raj Ojha, Samuel Padgham, Song Yi Shin, Frida Leon Olm- edo, Christopher R. Woodman, Andreea Trache Voltage-gated K Channels (Boards LB34 - LB41) L1925-Pos Board LB34 RILUZOLE INHIBITS K V 4.2 CHANNELS ACTING ON THE CLOSED AND CLOSED INACTIVATED STATES. David O. Pacheco Rojas, Mayra Delgado Ramírez, Kathya Villatoro, Eloy G. Moreno Galindo, Aldo Rodríguez- Menchaca, José A. Sánchez Chapula, Tania Ferrer Villada L1926-Pos Board LB35 ENDOCANNABINOID-LIKE COMPOUNDS AS MODULATORS OF THE CAR- DIAC KV7.1/KCNE1 CHANNEL. Irene Hiniesto Iñigo , Siri Lundholm, Johan E. Larsson, Sara I. Liin L1927-Pos Board LB36 EXPLORING HERG GATING THROUGH MD SIMULATIONS AND NETWORK ANALYSIS. Flavio Costa L1928-Pos Board LB37 TWO MEMBERS OF THE KCNQ FAMILY OF VOLTAGE-GATED POTASSIUM CHANNELS SHOW UNIQUE RESPONSES TO MODULATION BY POLYUNSAT- URATED FATTY ACIDS. Damon J.A. Frampton , Johan E. Larsson, Sara I. Liin L1929-Pos Board LB38 FUNCTIONAL UPREGULATION OF HERG1B ION CHANNELS BY DIRECT INTERACTIONS WITH HERG1A N-TERMINAL PAS AND N-LINKER DO- MAINS. Ashley A. Johnson , Taylor R. Crawford, Matt C. Trudeau L1930-Pos Board LB39 BK CHANNEL MODULATION BY THE GAMMA-SUBUNIT POSITIVELY CHARGED PEPTIDES VIA ELECTROSTATIC INTERACTIONS WITH THE CALCIUM-BOWL SITE. Guanxing Chen , Qin Li, Jiusheng Yan L1931-Pos Board LB40 EVALUATION OF AN AUTISM-ASSOCIATED KCNMB2 VARIANT ON BK CHANNEL PROPERTIES. Hans J. Moldenhauer , Andrea L. Meredith L1932-Pos Board LB41 OPTIMIZATION OF A HIGH-THROUGHPUT LIPOSOMES FLUORESCENCE ASSAY FOR THE SCREENING OF DRUG LIBRARIES WITH POTENTIAL THERAPEUTIC USE FOR ION CHANNEL DYSFUNCTION RELATED DISEASES. Emily Marian Ostermaier , Doris M. Cortes, Luis G. Cuello Ion Channels, Pharmacology, and Disease (Boards LB42 - LB43) L1933-Pos Board LB42 TOXIN AUTORESISTANCE IN POISON BIRDS AND FROGS IS NOT ROOTED IN TARGET SODIUM CHANNEL MUTATIONS. Fayal Abderemane-Ali , Nathan D. Rossen, Megan E. Kobiela, Robert A. Craig II, Catherine E. Gar- rison, Lauren A. O’Connell, J. Du Bois, John P. Dumbacher, Daniel L. Minor L1934-Pos Board LB43 PATHOLOGICAL STATE OF MALIGNANT HYPERTHERMIA ASSOCIATED R615C MUTATION REVEALED USING CRYO-EM. Omid Haji-Ghassemi

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L1913-Pos Board LB22 ROLE OF CHOLESTEROL IN THE FUNCTION OF CYSTIC FIBROSIS CORREC- TORS AND POTENTIATORS. Dorna Ravamehr-Lake , Charles M. Deber L1914-Pos Board LB23 DIFFERENT A-CASEIN ASSOCIATION STATES AND THEM INTERACTION WITH LIPID VESICLES TO STUDY ANTIBACTERIAL ACTIVITY. Sara Anselmo , Giuseppe Sancataldo, Valeria Vetri L1915-Pos Board LB24 ROLE OF CHOLESTEROL ON ALPHA-CRYSTALLIN BINDING TO PHOSPHA- TIDYLSERINE MEMBRANE. Geraline Trossi-Torres , Raju Timsina, Nawal Khadka, Laxman Mainali L1916-Pos Board LB25 PIEZO1-INDUCED MEMBRANE CURVATURE CAUSES RAFT ASSOCIATION AND ALTERATION OF THE CHOLESTEROL DISTRIBUTION BETWEEN LEAF- LETS. Amanda Buyan , David Allender, Siewert J. Marrink, Michael Schick, Board LB26 EFFECTS OF DIFFERENT MEMBRANE LIPIDS ON THE FUNCTIONS OF THE LC3/GABARAP AUTOPHAGY PROTEIN FAMILY MEMBERS. Marina N. Iriondo, Asier Etxaniz, Yaiza R. Varela, Uxue Ballesteros, Javier H. Hervas, L. Ruth Montes, Félix M. Goñi , Alicia Alonso L1918-Pos Board LB27 EFFECTS OF MEMBRANE OXIDATION ON THE ACTIVITY OF THE 1A HUMAN SEROTONIN RECEPTOR. Ahmed ElBaradei , Zikai Wang, Noah Board LB28 THE MITOCHONDRIA-TARGETED PEPTIDE SS-31 MODULATES THE THER- MOTROPIC PROPERTIES OF CARDIOLIPIN-CONTAINING MODEL MEM- BRANES. Emily Ng , Jeffrey D. Tamucci, Heidi Erlandsen, Hazel H. Szeto, Nathan N. Alder L1920-Pos Board LB29 THE INFLUENCE OF CHOLESTEROL IN A MYELIN-LIKE BILAYER ON MYELIN BASIC PROTEIN. Jennica Träger , Annette Meister, Gerd Hause, George Harauz, Dariush Hinderberger L1921-Pos Board LB30 STEPWISE AND COOPERATIVE MEMBRANE BINDING AND TETHERING BY TANDEM C2 DOMAINS OF EXTENDED SYNAPTOTAGMINS REVEALED BY OPTICAL TWEEZERS. Jinghua Ge , Xin Bian, Lu Ma, Yiying Cai, Yanghui Li, Yasunori Saheki, Erdem Karatekin, Pietro De Camilli, Yongli Zhang Mechanosensation (Boards LB31 - LB33) L1922-Pos Board LB31 SOFT POLYDIMETHYLSILOXANE-SUPPORTED LIPID-BILAYERS FOR STUDY- ING T-CELL INTERACTIONS. Anna H. Lippert , Ivan Dimov, Alex Winkel, Jane Humphrey, James T. McColl, Kevin Chen, Ana M. Santos, Edward Jenkins, Kristian Franze, Simon Davis, David Klenerman L1923-Pos Board LB32 RESPONSE OF FIBRIN NETWORK TO APPLIED OSCILLATION DETECTED BY PIXEL INTENSITY FLUCTUATIONS. Qingda Hu , Tessa A. Morris, Anna Grosberg, Alex J. Levine, Elliot Botvinick Ben Corry L1917-Pos Malmstadt L1919-Pos

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