Biophysical Society 65th Annual Meeting Program Guide

Enzyme Function, Cofactors, and Post-translational Modifications (Boards LB12 - LB16) Board LB12 GENTISATE 1,2-DIOXYGENASE FROM ASPERGILLUS NIGER : FUNCTIONAL CHARACTERIZATION AND IDENTIFICATION OF RESIDUES CRITICAL FOR CATALYSIS. Patrick Semana , Justin Powlowski L1969-Pos Board LB13 STRUCTURAL BASIS FOR LONG CHAIN ISOPRENOID SYNTHESIS BY THE HUMAN CIS -PRENYLTRANSFERASE COMPLEX. Michal Lisnyansky Bar-El L1970-Pos Board LB14 COMPARISON OF THE PEROXIDASE FUNCTION OF GLOBIN-DEHALOPER- OXIDASES-A AND B. Nikhila Kashyap Dhanvantari Madhuresh , Stefan Franzen L1971-Pos Board LB15 A SYNTHETIC MINIMAL PATHWAY FOR THE REGENERATION OF REDOX COFACTORS. Michele Partipilo, Eleanor J. Ewins , Bert Poolman, Dirk Jan Board LB16 A COMPUTATIONAL STUDY OF THE ROLE OF THE E3 LIGASE IN THE UBIQ- UITINATION REACTION. Jay-Anne Johnson Intrinsically Disordered Proteins (IDP) and Aggregates III (Boards LB17 - LB21) L1973-Pos Board LB17 MEDIN OLIGOMER MEMBRANE PORE FORMATION: A POTENTIAL MECHANISM OF VASCULAR DYSFUNCTION. Scott M. Younger , Hyunbum Jang, Hannah A. Davies, Martin Niemiec, Joe G.N. Garcia, Ruth Nussinov, Raymond Q. Migrino, Jillian Madine, Fernando M. Teran Arce L1974-Pos Board LB18 HIV-TAT PROTEIN GENERATES ITS OWN HIGHLY TOXIC AMYLOID FI- BRILS. Alina L. Popescu Hategan , Edward L. Mertz, Joseph Steiner, Elena Karnaukhova, Mario A. Bianchet, Lisa Henderson, Olav Zimmerman, Jeff Kowalak, Emilios K. Dimitriadis, Avindra Nath L1975-Pos Board LB19 INHIBITION OF TAU PROTEIN AGGREGATION USING SMALL MOLECULE INHIBITORS AND IMMUNOTHERAPIES. Sanela Martic L1976-Pos Board LB20 THE SARS-COV-2 NUCLEOCAPSID PROTEIN IS DYNAMIC, DISORDERED, AND PHASE SEPARATES WITH RNA. Jasmine Cubuk , Jhullian J. Alston, Jeremias J. Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory Bowman, Kathleen B. Hall, Andrea Soranno, Alex S. Board LB21 CHARACTERIZING VESICLE BINDING AFFINITY AND CONFORMATION OF POST-TRANSLATIONALLY MODIFIED ALPHA-SYNUCLEIN BY SINGLE MOL- ECULE FLUORESCENCE SPECTROSCOPY. Buyan Pan , E. James Petersson, Elizabeth Rhoades RNA Structure and Dynamics (Boards LB22 - LB23) L1978-Pos Board LB22 INVESTIGATING THE DYNAMICS OF POLY(ADP-RIBOSE) BY SINGLE MOLECULE FLUORESCENCE RESONANCE ENERGY TRANSFER (SMFRET). Mohsen Badiee L1968-Pos Slotboom L1972-Pos Holehouse L1977-Pos

Friday, February 26 Friday Late Posters ( Board s LB1 - LB63) Protein Structure and Conformation III (Boards LB1 - LB6) L1957-Pos Board LB1 PRELIMINARY STRUCTURAL CHARACTERIZATION OF C. ELEGANS HOX TRANSCRIPTION FACTOR LIN-39 AND ITS MUTANT LIN-39(CCC16). Kris- tina Lodahl, Rebecca Surma-Heine, Andrea K. Kalis, Kim N. Ha L1958-Pos Board LB2 DIFFERENCES IN LOCAL STRUCTURAL DYNAMICS OF BACTERIAL TRAN- SCRIPTION ELONGATION COMPLEX UPON BINDING OF NUSG AND RFAH TRANSCRIPTION FACTORS. Jose Alejandro Molina Ramirez , Steve Silletti, Irina Artsimovitch, Elizabeth A. Komives, Cesar A. Ramirez-Sarmiento L1959-Pos Board LB3 STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE BESTRO- PHIN2 ANION CHANNEL. Aaron P. Owji L1960-Pos Board LB4 THE CONFORMATION AND DYNAMICS OF LRRK2 THAT ARE ASSOCIATED WITH ITS ACTIVATION AND PARKINSON’S DISEASE PATHOGENESIS. Jui-Hung Weng , Phillip C. Aoto, Steven Silletti, Susan S. Taylor L1961-Pos Board LB5 TROPOELASTIN: BIOMECHANICS IN DIFFERENT PHYSIOLOGICAL ENVI- RONMENTS AND MECHANISMS OF ELASTICITY. Chengeng Yang , Anna Board LB6 USING GRAPHS TO ANALYZE SARS-COV2 SPIKE MUTATIONS. Pedro D. Manrique , Rory C. Henderson, Srirupa Chakraborty, Kien Nguyen, Rachael A. Mansbach, Kevin J. Wiehe, Bette Korber, Sandrasegaram Gnanakaran Protein Dynamics and Allostery II (Boards LB7 - LB11) L1963-Pos Board LB7 A FREE-ENERGY LANDSCAPE APPROACH REVEALS THE GLOBAL CONFOR- MATIONAL DYNAMICS OF PROTEASOMAL ATPASES. Rui Fang, Jason Hon, Mengying Zhou, Ying Lu L1964-Pos Board LB8 ROLE OF PROTEIN-SUGAR INTERACTIONS IN MAINTENANCE OF PRO- TEIN DYNAMICS AND FUNCTION IN SMALL LEUCINE-RICH PROTEOGLY- CANS. Rajas M. Rao , Marc Guéroult, Nicolas Belloy, Jean-Marc Crowet, Stéphane Brézillon, Manuel Dauchez, Stephanie Baud L1965-Pos Board LB9 EFFECT OF NON-NATIVE INTERACTIONS ON CLP ATPASE-MEDIATED DEG- RADATION OF KNOTTED PROTEINS REVEALED USING MOLECULAR DY- NAMICS. Hewafonsekage Yasan Y. Fonseka , Alex Javidi, Luiz F.L. Oliveira, Cristian Micheletti, George Stan L1966-Pos Board LB10 ALLOSTERIC MODULATION OF ACE2 CONFORMATION UPON BINDING TO SPIKE PROTEIN OF SARS-COV-2. Duen-Shian Wang , Hamed S. Hayatshahi, Jin Liu L1967-Pos Board LB11 A TALE OF TWO BINDING PATHWAYS: MOLECULAR DYNAMICS STUDY OF THE GID1A-GA-GAI SYSTEM. John Patterson , Charles C. David, Marion Wood, Xiaolin Sun, Donald J. Jacobs, Erik H.A. Rikkerink Tarakanova L1962-Pos

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