Biophysical Society 65th Annual Meeting Program Guide

No Abstract 2:30 pm INVITED SUBGROUP SPEAKER. Nancy Carrasco 15-Subg 2:55 pm

3:15 pm

subgroup business meeting

No Abstract 3:30 pm LASER-SCANNING MICROSCOPY WITH SINGLE-PHOTON DETEC- TOR ARRAY: DECONSTRUCTING THE PHOTON STREAM FROM YOUR FLUORESCENCE SAMPLE . Giuseppe Vicidomini 19-Subg 4:00 pm BEYOND IMAGING FCS - MULTIPARAMETRIC FLUORESCENCE MICROS- COPY. Thorsten Wohland 4:30 pm rapid fire speakers selected from posters 4:55 pm young fluorescence investigator awardee 5:20 pm presentation of weber award 5:25 pm weber awardee 5:50 pm concluding remarks Cryo-EM Symposium 2:00 pm - 6:00 pm Subgroup Chair Charles (Chuck) Sindelar, Yale University, USA Program Co-Chairs Andres Leschziner, University of California, San Diego, USA Michael Cianfrocco, University of Michigan, USA 2:00 pm opening remarks No Abstract 2:05 pm CRYO EM OF DYNAMIC COMPLEXES. Helen Saibil No Abstract 2:35 pm REVEALING MITOCHONDRIAL ARCHITECTURE IN VITRIFIED CELLS BY CRYOSTEM TOMOGRAPHY. Sharon G. Wolf No Abstract 2:57 pm RESOLVING PROTEIN DYNAMICS IN SITU WITH DEEP LEARNING. Dimitry Tegunov No Abstract 3:19 pm ISOLDE: AN INTERACTIVE MOLECULAR DYNAMICS APPROACH TO MAC- ROMOLECULAR MODEL BUILDING IN EXPERIMENTAL MAPS. Tristan Croll No Abstract 3:37 pm MECHANISTIC INSIGHTS INTO MOLECULAR MACHINES THAT REGULATE GENE EXPRESSION. Lori A. Passmore 3:59 pm coffee break No Abstract 4:14 pm TUNNELS FOR LIPID TRANSPORT ACROSS THE BACTERIAL CELL ENVE- LOPE. Gira Bhabha No Abstract 4:36 pm MONOLAYER GRAPHENE GRIDS ENABLE 2.6-Å RECONSTRUCTION OF 52- KDA STREPTAVIDIN. Yimo Han No Abstract 4:54 pm VISUALIZING THE SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING ANTIBODIES. Lexi Walls No Abstract 5:12 pm INVITED SUBGROUP SPEAKER. Katerina Naydenova No Abstract 5:30 pm PUSHING THE LIMITS OF CRYO-EM FOR G PROTEIN-COUPLED RECEP- TORS. Radostin Danev 5:52 pm closing remarks

M O N D A Y

MECHANISTIC INSIGHTS FROMMOLECULAR DYNAMICS SIMULATIONS OF LARGE-SCALE CONFORMATIONAL TRANSITIONS IN THE INDY TRANSPORT CYCLE. Noah Trebesch , David B. Sauer, Da-Neng Wang, Emad Tajkhorshid No Abstract 3:10 pm STRUCTURAL INSIGHT INTO TOXIN SECRETION BY CONTACT DEPENDENT GROWTH INHIBITION OF TRANSPORTERS. Susan K. Buchanan 3:35 pm coffee break 16-Subg 4:10 pm THE MOLECULAR DETERMINANTS FOR UNLOCKING SUBSTRATE TRANS- LOCATION IN GLUT TRANSPORTERS. David Drew No Abstract 4:35 pm ION PERMEATION IN NON-SELECTIVE CATION CHANNELS. Han Sun No Abstract 5:00 pm CRYO-EM AND FUNCTIONAL STUDIES OF RYRS CARRYING MUTATIONS LEADING TO “LEAKY” PHENOTYPE. Kavita Iyer , Yifan Hu, Ashok R. Nayak, Takashi Murayama, Nagomi Kurebayashi, Montserrat Samso No Abstract 5:15 pm ARCHITECTURE AND FUNCTION OF NEURONAL MACHINERY. Hiro Furukawa Bioengineering Symposium 2:00 pm - 6:00 pm Subgroup Chair Samir Iqbal, University of Texas Rio Grande Valley, USA No Abstract 2:00 pm FLEXIBLE MULTIFUNCTIONAL FIBERS FOR BRAIN INTERFACING. Xiaoting Jia 17-Subg 2:45 pm RECONSTRUCTING PROTEIN STRUCTURE AND DYNAMICS FROM EXPERI- MENTAL OBSERVABLES. Andrew Ferguson 3:30 pm postdoc recognition 4:15 pm break No Abstract 4:30 pm ENGINEERING MINIATURE HUMAN TISSUES FOR DISEASE MODELING AND DRUG DEVELOPMENT. Salman Khetani No Abstract 5:15 pm INVITED SUBGROUP SPEAKER. Ahmad Khalil. Biological Fluorescence Symposium 2:00 pm - 6:00 pm Subgroup Chair Jay Knutson, NHLBI, NIH, USA 2:00 pm introduction 2:05 pm tribute to arthur g. szabo No Abstract 2:15 pm THROUGH THE LOOKING-GLASS: IMAGING-BASED CHROMOSOME CON- FORMATION CAPTURE IN SINGLE CELLS. Marcelo Nollman 18-Subg 2:45 pm COHERENT RAMAN SCATTERING MICROSCOPY FOR QUANTITATIVE LABEL-FREE BIOIMAGING. Paola Borri

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