Biophysical Society 65th Annual Meeting Program Guide

356-Pos B oard B290 STRUCTURAL DYNAMICS AND ENERGETICS OF GLUCOSE TRANSPORT VIA RICE SWEET SUGAR TRANSPORTER. Ankita Gupta , Ramasubbu Sankara- ramakrishnan 357-Pos B oard B291 ENERGETICS OF SUBSTRATE BINDING AND CONFORMATIONAL CHANGE OF THE BILE ACID TRANSPORTER ASBT NM . Fiona Naughton , Patrick Becker, Alexander D. Cameron, Oliver Beckstein 358-Pos B oard B292 IN VIVO AND IN VITRO CHARACTERIZATIONS OF NANOBODIES RAISED AGAINST THE MELIBIOSE PERMEASE MELB OF SALMONELLA TYPHIMURI - UM . Satoshi Katsube , Katleen Willibal, Elena B. Tikhonova, Hariharan Parameswaran, Sangama Vemulapally, Els Pardon, H. Ronald Kaback, Jan Steyaert, Lan Guan 359-Pos B oard B293 DRUG EFFECTS ON HUMAN NA(+)/CA(2+)EXCHANGER AND IMPLICA- TIONS FOR DRUG DEVELOPMENT. Maria Barthmes , Andre Bazzone, Marta Lemme, Sonja Stoelzle-Feix, Andrea Bruggemann, Michael George, Niels Fertig 360-Pos B oard B294 MECHANISTIC INSIGHT INTO PEPTIDE-BASED EFFLUX PUMP INHIBITORS AGAINST PATHOGENIC BACTERIA. Chloe J. Mitchell , Charles M. Deber 361-Pos B oard B295 PUMP, REST AND REPEAT: SINGLE MOLECULE MEASUREMENTS REVEAL MODE-SWITCHING IN THE MAMMALIAN BRAIN V-ATPASE. Eleftherios I. Kosmidis , Julia Preobraschenski, Christopher Shuttle, Salome Veshaguri, Peter J. Johnson, Jesper L. Pedersen, Reinhard Jahn, Dimitrios Stamou 362-Pos B oard B296 ALTERNATING BINDING OF PHOSPHOLAMBAN AND DWORF TO SERCA DURING TRANSIENT ELEVATIONS OF CYTOSOLIC CALCIUM. Sean R. Cleary , Marsha P. Pribadi, Ellen E. Cho, Xuan Fang, Jaroslava Seflova, Jordan R. Beach, Peter M. Kekenes-Huskey, Seth L. Robia 363-Pos B oard B297 DISPLACEMENT OF THE NA + /K + -PUMP’S TRANSMEMBRANE DOMAINS DEMONSTRATE CONSERVED CONFORMATIONAL CHANGES IN P-TYPE 2 ATPASES. Victoria C. Young , Pablo Artigas 364-Pos B oard B298 INSIGHT INTO SODIUM PUMP REGULATION BY FXYD PROTEINS. Jaroslava Seflova , John Q. Yap, Christine E. Delligatti, Marsha P. Pribadi, Pablo Arti- gas, Julie Bossuyt, Seth L. Robia 365-Pos B oard B299 THE USE OF THIOFLAVIN T TO ESTIMATE AND MEASURE THE PLASMA MEMBRANE POTENTIAL IN SACCHAROMYCES CEREVISIAE . Antonio Peña EPR and NMR: Spectroscopy and Imaging (Boards B300 - B305) 366-Pos B oard B300 “ONE STOP SHOP” FOR NMR-BASED BIOMOELCULAR RESEARCH. Woong- B oard B301 PARAMAGNETIC NMR SPECTROSCOPY OF A TRI-NUCLEAR COPPER CEN- TER FROM A MULTICOPPER OXIDASE, LACCASE. Rubin Dasgupta 368-Pos B oard B302 STRUCTURE AND DYNAMICS OF FICOLL (POLYSUCROSE). Venketesh Thrithamara Ranganathan , Yun Liu, Anand Yethiraj hee Lee 367-Pos

369-Pos B oard B303 INVESTIGATING CHROMATIN DYNAMICS IN HETEROCHROMATIN ENVI- RONMENTS BY SOLID-STATE NMR SPECTROSCOPY. Nesreen Elathram , Bryce Ackermann, Galia T. Debelouchina 370-Pos B oard B304 15 N BIFUNCTIONAL SPIN LABEL: PUSHING THE LIMITS OF ANGULAR RESO- LUTION OF MUSCLE MYOSIN. Yahor Savich , Megan R. McCarthy, Stefan Stoll, David D. Thomas 371-Pos B oard B305 HOW ACCURATE ARE PRE-DERIVED DISTANCES? COMBINED MD AND EXPERIMENTAL STUDY OF SPIN-LABELED GB1 DOMAIN. Olga Lebedenko, Sergei A. Izmailov , Dmitrii Luzik, Nikolai Skrynnikov Molecular Dynamics I (Boards B306 - B328) 372-Pos B oard B306 DEEP LEARNING BASED OPTIMIZATION OF LENNARD-JONES PARAME- TERS FOR THE DRUDE GENERAL FORCE FIELD (DGENFF). Payal Chatterjee , Mert Y. Sengul, Alexander D. MacKerell 373-Pos B oard B307 MASSIVELY PARALLEL MACHINE LEARNING DRIVEN MULTISCALE SIMULA- TIONS TO EXPLORE RAS-RAF BIOLOGY. Helgi I. Ingólfsson 374-Pos B oard B308 PREDICTION OF ABSOLUTE BINDING AND UNBINDING KINETICS ON TIMESCALES OF A MINUTE FROM SUB-MICROSECOND MD SIMULA- TIONS. Steffen Wolf , Benjamin Lickert, Simon Bray, Gerhard Stock 375-Pos B oard B309 HOOGSTEEN BASE PAIRING IN DNA: EFFECTS OF FORCE FIELD MODELS ON FREE ENERGY AND TRANSITION PATHWAYS. Sharon E. Stone , Dhiman Ray, Ioan Andricioaei 376-Pos B oard B310 THE VARIATIONALLY DERIVED INTERMEDIATES METHOD TO CALCULATE FREE ENERGY DIFFERENCES. Martin Reinhardt , Helmut Grubmueller 377-Pos B oard B311 HAMILTONIAN REPLICA EXCHANGE WITH SOLUTE TEMPERING AND BIASING POTENTIALS (HREST-BP): APPLICATIONS IN ANTIBODY GLYCOEN- GINEERING. Gene Chong , Alexander D. MacKerell 378-Pos B oard B312 USING LAMBDA DYNAMICS TO STUDY PROTONATION STATES OF GLIC. Paul Bauer , Noora Aho, Anton Jansen, Rebecca J. Howard, Berk Hess, Gerrit Groenhof, Erik R. Lindahl 379-Pos B oard B313 MD SIMULATION OF SOLVATED DAFP-1-ICE SURFACE BINDING USING UMBRELLA SAMPLING. Benjamin M. Harless 380-Pos B oard B314 WAYPOINT GRAPH GENERATION WITH GROWING NEURAL GASES FOR PATHFINDING APPLICATIONS IN MOLECULAR DYNAMICS SIMULA- TIONS. Moeen Meigooni , Emad Tajkhorshid 381-Pos B oard B315 ADAPTIVE SAMPLING USING A GEOMETRIC BROWNIAN MOTION MODEL TO PREDICT MD TRAJECTORY MOBILITY ON A FREE ENERGY SUR- FACE. Ekaterina D. Kots , Derek M. Shore, Harel Weinstein 382-Pos B oard B316 AUTOMATED IDENTIFICATION OF COLLECTIVE VARIABLES AND META- STABLE STATES FROMMOLECULAR DYNAMICS DATA. Yasemin Bozkurt Varolgunes, Tristan Bereau, Joseph F. Rudzinski

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