Biophysical Society 65th Annual Meeting Program Guide

Anneliese Faustino, Johns Hopkins University, USA 953-Pos , Board B3

Haixing Li, Columbia University, USA 526-Plat

MAPPING STRUCTURAL INTERMEDIATES DURING CO-TRANSLATIONAL FOLDING OF HSP70 WITH CROSSLINKING MASS SPECTROMETRY. Valeria Guzman Luna, University of Wisconsin-Madison, USA 954-Pos , Board B4 INTERACTION BETWEEN RIBOSOME-BOUND NASCENT PROTEINS AND A

THE ROLE TRNA-MEDIATED REGULATION OF RIBOSOME DYNAMICS PLAYS IN FRAMESHIFTING BY +1 FRAMESHIFT-INDUCING TRNAS. Louisa Mezache, The Ohio State University, USA 743-Pos , Board B194 TARGETING THE VASCULAR ENDOTHELIAL BARRIER TO PREVENT NANOSCALE CARDIAC REMODELING: A NOVEL STRATEGY TO PREVENT ATRIAL FIBRILLATION. Molly Mollica, University of Washington, USA 811-Pos , Board B262 MEASURING SINGLE-CELL PLATELET FORCES VIA MICROCONTACT- PRINTED, REFERENCE-FREE TRACTION FORCE MICROSCOPY REVEALS RELATIONSHIPS BETWEEN CELL SHAPE, F-ACTIN LOCALIZATION, AND FORCE. Sara Osorio Valencia, Loyola University Chicago, USA 534-Plat TRPP1 CHANNEL CALCIUM SIGNALING AS A KEY DETERMINANT OF MYOGENESIS. Jinho Park, University of Central Florida, USA 774-Pos, Board B225 CROWDING TUNES THE ORGANIZATION AND MECHANICS OF ACTIN BUNDLES INDUCED BY ACTIN CROSSLINKING PROTEINS. Maria Queralt-Martin, Universitat Jaume I, Spain 750-Pos , Board B201 ASSESSING THE ROLE OF ELECTROSTATIC INTERACTIONS IN THE MECHANISM OF BETA-BARREL CHANNEL GATING. Priti Roy, Indian Institute of Science Education and Research- Kolkata 619-Pos , Board B70 DISULFIDE REDUCTION ALLOSTERICALLY DESTABILIZES THE Β-LADDER SUB-DOMAIN ASSEMBLY WITHIN THE NS1 DIMER OF ZIKV. Michelle Sahai, University of Roehampton, United Kingdom 594-Pos , Board B45 USING COMPUTATIONAL AND NEUROBIOLOGICAL METHODS TO CHARACTERISE THE STIMULANT PROPERTIES OF NOVEL PSYCHOACTIVE SUBSTANCES (NPS) AT THE DOPAMINE TRANSPORTER. Prakash Shrestha, Boston Children’s Hospital, USA 906-Pos , Board B357 SINGLE MOLECULE SHAPE DETERMINATION OF BIOMOLECULES USING DNA NANOSWITCH CALIPERS. Yaqiang Wang, University of California, Los Angeles, USA 669-Pos , Board B120 A STRUCTURALLY CONSERVED HUMAN AND TETRAHYMENA TELOMERASE CATALYTIC CORE. Shiying Zhu, Bio21 Institute, Australia 689-Pos , Board B140 C-TERMINUS AMIDATION INFLUENCES BIOLOGICAL ACTIVITY AND MEMBRANE INTERACTION OF MACULATIN 1 1. Thursday, February 25 Wooyoung Choi, Van Andel Institute, USA 1018-Pos , Board B68 STRUCTURE BASIS AND GATING MECHANISM OF CALCIUM

SPECIFIC REGION OF THE RIBOSOMAL SURFACE. Soonwoo Hong, University of Texas at Austin, USA 1308-Pos , Board B358

CORRELATION BETWEEN SPECTROSCOPIC AND STRUCTURAL FEATURES OF DIMERIC DNA-TEMPLATED SILVER NANOCLUSTERS USING MASS SPECTROMETRY. Wen Ma, University of California, San Diego, USA 1208-Pos , Board B258 MOLECULAR MECHANISM OF FORCE GENERATION BY THE ACTIN- MYOSIN COMPLEX DURING CARDIAC MUSCLE CONTRACTION. Abigail Nagle, University of Washington, USA 1224-Pos , Board B274 A NOVEL METHOD TO MEASURE MYOFIBRIL STRAIN IN INTACT HUMAN STEM CELL DERIVED CARDIOMYOCYTES. James Osei-Owusu, Johns Hopkins University, USA 930-Plat STRUCTURES OF HUMAN PROTON-ACTIVATED CHLORIDE CHANNEL (PAC) REVEAL MECHANISM OF PH SENSING AND GATING. Lara Scofano, University of Oxford, United Kingdom 1196-Pos , Board B246 THE MOLECULAR BASIS OF THE REGULATION OF THE TMEM16A CA 2+ - ACTIVATED CL - CHANNEL BY THE LYSOSOMAL NPC1 PROTEIN. Pamela Swiatlowska, New York University, USA 1221-Pos , Board B271 MEMBRANE YOUNG’S MODULUS AS A FUNCTION OF PLAKOPHILIN-2 EXPRESSION: IMPLICATIONS TO ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY. Philip To, Johns Hopkins University, USA 1333-Plat PROBING THE IMPACT OF MOLECULAR CHAPERONES ON THE REFOLDABILITY OF THE E. COLI PROTEOME. Qi Wang, New Mexico Institute of Mining and Technology, USA 1094-Pos , Board B144 EXAMINATION OF BREAST-CANCER-ASSOCIATED LIPID TAIL LENGTH EFFECTS ON BILAYER OXYGEN PERMEABILITY. Xiaoan Wu, University of Miami, USA 1169-Pos , Board B219 NON-CANONICAL MECHANISM OF THE VSD-PD COUPLING IN KCNQ1/ KCNE1 CHANNELS. Friday, February 26 Mac Kevin Braza, University of California, San Diego, USA 1443-Pos , Board B45 IN SILICO INSIGHTS ON THE ALLOSTERIC MODULATION OF THE ΜU-OPIOID RECEPTOR AND G PROTEIN COMPLEX IN THE PRESENCE OF AGONIST LIGAND BU72 AND POTENTIAL POSITIVE ALLOSTERIC MODULATOR BMS-986121. Mandy Erkelens, Leiden University, the Netherlands 1531-Pos , Board B133 (A)SPECIFIC DNA BINDING OF ARCHAEAL HISTONES, THE FORMATION AND POSITIONING OF HYPERNUCLEOSOMES.

HOMEOSTASIS MODULATOR 2 CHANNEL. Bojian Ding, Stony Brook University, USA 1352-Plat

STRUCTURAL PERSPECTIVE INTO ACTIVATION OF ARP2-3 COMPLEX FOR NUCLEATING LINEAR AND BRANCHED ACTIN ASSEMBLIES.

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