Biophysical Society 65th Annual Meeting Program Guide

1141-Pos B oard B191 PIEZO1 IS ESSENTIAL FOR CELL REMODELING ON MICROPATTERNS. Mo- hammad Reza Bahrani Fard, Deekshitha Jetta, Katie Munechika, Susan Z. Hua 1142-Pos B oard B192 MOTILITY AND BEHAVIOR OF S. COERLEUS DURING REGENERATION. Janet Y. Sheung , Megan Otsuka, Athena Lin, Gabriella Seifert, Wallace B oard B193 ALTERED TENSION TRANSMISSION VIA FOCAL ADHESIONS IN DYSTRO- PHIC MUSCLE CELLS DYSREGULATES MECHANOTRANSDUCTION. Maria Paz Ramirez Lopez , Sophia J. Wenthe, Eric J. Aird, James M. Ervasti, Wendy R. Gordon 1144-Pos B oard B194 SUBCELLULAR INVESTIGATION OF THE INTERPLAY BETWEEN MEMBRANE TENSION AND MECHANOSENSITIVITY USING FORCE-CONTROLLED MICROPIPETTES. Ines Lüchtefeld , Christoph Gäbelein, Janos Voros, Boris Martinac, Tomaso Zambelli, Massimo Vassalli 1145-Pos B oard B195 Α-CATENIN FORMS AN UNCONVENTIONAL SLIP BOND WITH ACTIN THAT SWITCHES COOPERATIVELY INTO A CATCH BOND. Marios Sergides, Clau- dia Arbore, Lucia Gardini, Francesco S. Pavone, Marco Capitanio 1146-Pos B oard B196 MICROENVIRONMENT STIFFNESS REQUIRES FETAL EXTRACELLULAR PROTEINS TO INCREASE CARDIOMYOCYTE PROLIFERATION IN NEONATAL MOUSE. Xinming Wang , Paul Park, Samuel E. Senyo 1147-Pos B oard B197 COMPUTATIONAL MODEL OF E-CADHERIN CLUSTERING UNDER CORTI- CAL TENSION. Yang Chen , Colin McNabb, Tamara Bidone 1148-Pos B oard B198 SPATIAL MODELING OF YAP/TAZ MECHANOTRANSDUCTION REVEALS HOWMULTIPLEXED PHYSICAL CUES TRANSFER INFORMATION TO THE NUCLEUS. Kiersten Scott, Padmini Rangamani, Stephanie I. Fraley 1149-Pos B oard B199 MODIFIED N-LINKED GLYCOSYLATION STATUS PREDICTS TRAFFICKING DE- FECTIVE PIEZO1 CHANNEL MUTATIONS. Jinyuan Li, Chai Ann Ng, Delfine Cheng, Charles D. Cox 1150-Pos B oard B200 SELF-PROPELLED VESICLES DRIVEN BY INTERNAL ACTIVE FILA- MENTS. Thorsten Auth , Clara Abaurrea-Velasco, Gerhard Gompper 1151-Pos B oard B201 BIOPHYSICS OF THERMAL AND MECHANICAL ULTRASONIC NEUROMOD- ULATION. Muye He, Arnd Pralle 1152-Pos B oard B202 TIME LAPSE NANOSCALE IMAGING OF THE SURFACE OF MECHANO- SENSORY STEREOCILIA BUNDLES IN LIVE MAMMALIAN AUDITORY HAIR CELLS. Carolina Galeano-Naranjo , A. Catalina Velez-Ortega, Gregory I. Frolenkov Excitation-Contraction Coupling (Boards B203 - B211) 1153-Pos B oard B203 CHANGES IN CONTRACTILE FUNCTION OF SINGLE CARDIOMYOCYTES FROM THE DIFFERENT HEART CHAMBERS IN TYPE 2 DIABETES MEL- LITUS. Tatiana Myachina , Xenia Butova, Ksenia Sokolova, Irina Gette, Anastasia Khokhlova Marshall 1143-Pos

1154-Pos B oard B204 EFFECTS OF POINT MUTATIONS OF DYSFERLIN ON CA 2+ SIGNALING IN MURINE SKELETAL MYOFIBERS. Valeriy I. Lukyanenko , Joaquin M. Muriel, Robert J. Bloch 1155-Pos B oard B205 THE ROLE OF T-TUBULE ORGANIZATION IN REGULATION OF INTRACEL- LULAR CA 2+ HANDLING BY MUSCARINIC RECEPTOR STIMULATION IN VEN- TRICULAR MYOCYTES. Andriy E. Belevych , Vladimir Bogdanov, Dmitry A. Terentyev, Sandor Gyorke 1156-Pos B oard B206 CLEAVAGE AND MIGRATION OF JUNCTOPHILIN 1 IN MUSCLE OF PATIENTS WITH CYTOSOLIC LEAK OF STORED CALCIUM. Eshwar Reddy Tammineni , Lourdes Figueroa, Natalia Kraeva, Carlo Manno, Sheila Riazi, Eduardo Rios 1157-Pos B oard B207 TUBULAR (T-) SYSTEM SOCE-PMCA BALANCE IS REGULATED BY RYR LEAK IN RESTING SKELETAL MUSCLE. Luke Pearce, Cedric Lamboley, Crystal Seng, Aldo Meizoso Huesca, Daniel P. Singh, Christopher J. Barclay, Bradley S. Launikonis 1158-Pos B oard B208 AUTOSOMAL-DOMINANT CASQ2-K180R CAUSES CPVT BY ALTERING INTRA-SR CALCIUM BUFFERING WITHOUT REDUCING CASQ2 PROTEIN LEVELS. MatthewWleklinski , Shan Parikh, Daniel Blackwell, Bjorn C. Knollmann 1159-Pos B oard B209 ARRHYTHMOGENIC CROSSTALK OF SODIUM, CALCIUM, REACTIVE OXY- GEN SPECIES AND CAMKII SIGNALING IN THE FAILING RABBIT VENTRICU- LAR MYOCYTE - INSIGHTS FROM A COMPUTATIONAL STUDY. Caroline Liu, Haibo Ni, Bence Hegyi, Donald M. Bers, Eleonora Grandi, Stefano Morotti 1160-Pos B oard B210 CRYO-EM STUDIES OF PHOSPHOMIMETIC AND PHOSPHO-NULL TRIPLE MUTANTS OF CARDIAC RYANODINE RECEPTOR (RYR2). Yifan Hu , Kavita Iyer, Ashok R. Nayak, Thomas Klose, Jose M. Eltit, Nagomi Kurebayashi, Takashi Murayama, Montserrat Samso 1161-Pos B oard B211 THE SARCOPLASMIC RETICULUM OXIDOREDUCTASE SYSTEMMODU- LATES LUMINAL CA 2+ REGULATION OF THE RYANODINE RECEPTOR IN CARDIAC DISEASE. Shanna Hamilton , Radmila Terentyeva, Tae Yun Kim, Benjamin Martin, Vladimir Bogdanov, Andriy E. Belevych, Christopher H. George, Sandor Gyorke, Bum-Rak Choi, Jonathan P. Davis, Dmitry A. Terentyev Voltage-gated K Channels (Boards B212 - B235) 1162-Pos B oard B212 HV1 PROTON CHANNEL OPENING TRANSITION REVEALED BY EXPERI- MENTAL AND COMPUTATIONAL APPROACHES. Ashley L. Bennett, I. Scott Ramsey 1163-Pos B oard B213 QUANTUM CALCULATIONS ON THE TRANSPORT OF PROTONS IN THE VOLTAGE SENSING DOMAIN OF THE KV1.2 POTASSIUM CHANNEL: MUL- TIPLE PATHS, CHARGED GROUPS, AND A SWITCH. Michael E. Green 1164-Pos B oard B214 MEASURING TEMPERATURE TIME COURSE USING MEMBRANE CAPACI- TANCE. Bernardo Pinto , Carlos Alberto Z. Bassetto Jr, Ramon Latorre, Francisco Bezanilla

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