Biophysical Society 65th Annual Meeting Program Guide

Friday, February 26 General Networking 9:00 am-10:00 am

substantial increased funding for fundamental biomedical research, as supported through congressional appropriations to federal agencies such as the NIH, NSF and DOE. Chair Eric Sundberg, Emory University , USA Speakers Michael Lauer, National Institutes of Health, USA Victoria McGovern, Burroughs Wellcome Fund, USA Jennifer Cama, House Appropriations Subcommittee on Labor, USA Platform Protein-Small Molecule Interactions 12:00 pm - 1:30 pm Chair Chair to be announced. No Abstract 12:00 pm P-GLYCOPROTEIN AND SMALL MOLECULE DRUG INTERACTIONS. Qinghai Zhang 1364-Plat 12:30 pm INFLUENCE OF FORCE ON THE FIMH CATCH BOND. Laura Carlucci , Wendy E. Thomas 1365-Plat 12:45 pm RAPID RANKING OF HETEROCYCLE-SIDE CHAIN STACKING INTERACTIONS BASED ON NEWMOLECULAR DESCRIPTORS. Andrea Bootsma 1366-Plat 1:00 pm PAVING THE WAY TO FIGHT MULTI-DRUG RESISTANT TUBERCULOSIS. Joaquim T. Marquês , Catarina Faria, Susana Santos, Maria da Soledade Santos, Filomena Martins, Rodrigo F.M. De Almeida 1367-Plat 1:15 pm DEVELOPMENT OF A HIGH-THROUGHPUT FLUORESCENT-BASED ASSAY TO ASSESS CYTOCHROME P450 3A7 ACTIVITY IN NEONATAL HUMAN LIVER MICROSOMES. Hannah M. Work , Sylvie E. Kandel, Jed N. Lampe Platform Membrane Protein Dynamics and Folding II 12:00 pm - 1:30 pm Chair Patrick van der Wel, University of Groningen, The Netherlands 1368-Plat 12:00 pm HOW LIPIDS MOBILISE MEMBRANE-BOUND CYTOCHROME C SEEN BY SOLID-STATE NMR. Patrick C.A. van der Wel 1369-Plat 12:30 pm NONEQUILIBRIUM DYNAMICS OF DIRECTIONAL H+ TRANS-MEMBRANE TRANSPORT. Saurabh Talele, John King 1370-Plat 12:45 pm A NEWLY DISCOVERED CLASS OF CURVATURE SENSITIVE PROTEINS: TRIMERIC ANNEXINS. Christoffer D. Florentsen , Guillermo S. Moreno Pescador, Alexander K. Sonne, Weria Pezeshkian, Joshua Daniels, Iliriana Qoqaj, Ali Asghar Hakami Zanjani, Himanshu Khandelia, Jesper Nyland- sted, Poul Martin Bendix 1371-Plat 1:00 pm MOLECULAR ASSEMBLY PATHWAY OF MITOCHONDRIAL SAM50 IN NA- TIVE MEMBRANES. Pankaj B. Tiwari, Radhakrishnan Mahalakshmi

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Catch up with colleagues and friends in the biophysical community during our networking hour. This event, which is open to all meeting attendees, provides meet-and-greet opportunities to enhance your virtual meeting experience. President’s Symposium: Building an Inclusive Biophysical Society 10:00 am - 11:00 am The scientific community, and indeed the world, has been faced with a great deal of introspection recently on the topics of inclusion and diversity. Organizations, associations, and institutions are faced with identifying a pathway that will create and sustain an inclusive community. However, before we begin to discuss what an inclusive Biophysical Society (BPS) would look like, we must first understand the baseline from which we begin. How do we define inclusion? Where are we starting from, and where do we want to go? How do we measure successful change in culture and attitudes outside of metrics? Join BPS President Catherine A. Royer as she leads a forum discussion based on input from BPS mem- bers, featuring invited speakers with extensive experience in working to enhance diversity, equity, and inclusion for scientists at their organiza- tions and across the scientific enterprise. We hope this one-hour session will serve as the beginning of the discussion for creating a welcoming, inclusive Biophysical Society. Chair Catherine A. Royer, Rensselaer Polytechnic Institute, USA Speakers Catherine A. Royer, Rensselaer Polytechnic Institute, USA David Asai, Howard Hughes Medical Institute, USA Bil Clemons, California Institute of Technology, USA Yadilette Rivera-Colón, Bay Path University, USA Billy Williams, American Geophysical Union, USA Exhibits 10:00 am - 5:00 pm Awards and 2021 Biophysical Society Lecture 11:00 am - 12:00 pm PRESENTATION OF AWARDS 11:00 am No Abstract 11:10 am VISUALIZING STRUCTURE, DYNAMICS AND INTERACTIONS OF COMPLEX MACROMOLECULAR ASSEMBLIES. Eva Nogales Responding to the Coronavirus Threat through Investments in Fundamental Biomedical Research 12:00 pm - 1:30 pm Effectively containing and limiting the spread of COVID-19, as well as responding to future pandemics by emerging, as yet unknown, infec- tious diseases, will require substantial increases in our knowledge of how this virus and other pathogens infect humans, how the human immune system responds to infection, and how to leverage this understanding to develop new vaccines and drugs. These needs can only be addressed by

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