Biophysical Society 65th Annual Meeting Program Guide

Protein Structure and Conformation III (Boards B1 - B34) 1399-Pos B oard B1 STRUCTURAL AND FUNCTIONAL ANALYSIS OF APOLIPOPROTEIN E MODIFICATION BY A LIPID PEROXIDATION PRODUCT, 4-HYDROXYNONE- NAL. Abbas Abdulhasan , Muhammad I. Abeer, Vasanthy Narayanaswami 1400-Pos B oard B2 DEVELOPMENT OF APOLIPOPROTEIN AI CHIMERA FOR TARGETED DRUG DELIVERY TO BREAST CANCER CELLS. Robert Mejia , Daanish Kulkarni, Vasanthy Narayanaswami 1401-Pos B oard B3 LIPID-PROTEIN FORCES PREDICT CONFORMATIONAL TRANSITION IN A MECHANOSENSITIVE CHANNEL. Csaba Daday , Bert L. de Groot 1402-Pos B oard B4 MEMBRANE INTERACTION OF HUMAN CLIC5 IS FACILITATED BY DIOXIDA- TION OF A CONSERVED CYSTEINE AND DRIVES MEMBRANE FUSION. Alisa Ferofontov , Pavla Vankova, Petr Man, Moshe Giladi, Yoni Haitin 1403-Pos B oard B5 STRUCTURAL DYNAMICS OF ANTIMICROBIAL PEPTIDES BASED ON HUMAN DEFENSIN 5 AMONG O-ANTIGENS OF BACTERIAL MEM- BRANE. Phoom Chumponanomakun , Prapasiri Pongprayoon 1404-Pos B oard B6 BRAVE NEW SURFACTANT WORLD REVISITED BY LIPASES: ACTIVATION AND UNFOLDING IN SDS. Mohamed Shehata , Aise Unlu, Emel Timucin 1405-Pos B oard B7 SINGLE PARTICLE ANALYSIS REVEALS THE ORGANIZATION OF THE MEMBRANE REMODELING PROTEIN CAVEOLIN-1 WITHIN DISC-SHAPED COMPLEXES. Bing Han , Jason C. Porta, Jessica L. Hanks, Yelena Peskova, Elad Binshtein, Kelly A. Dryden, Derek P. Claxton, Hassane S. Mchaourab, Erkan Karakas, Melanie D. Ohi, Anne K. Kenworthy 1406-Pos B oard B8 MECHANISM OF CHOLESTEROL TRANSLOCATION IN MYCOBACTE- RIA. Tian Chen , Fei Peng, Xiyao Cheng, Yongqi Huang, Zhengding Su 1407-Pos B oard B9 INVESTIGATION OF CYCLIC AMP BINDING INTERACTIONS WITH ISOLATED CYCLIC NUCLEOTIDE BINDING DOMAIN OF HCN1 CHANNEL USING ATOMISTIC MOLECULAR DYNAMICS SIMULATIONS AT MICROSECOND TIMESCALE. Matthew G. Brownd , Adithya Polasa, Mahmoud Moradi 1408-Pos B oard B10 EPR STUDIES OF KCNE3 IN PROTEOLIPOSOMES USING ELECTRON PARA- MAGNETIC RESONANCE (EPR) SPECTROSCOPY. Indra D. Sahu , Alberto Perez, Samuel Haralu, Matthew Scheyer, Gary A. Lorigan 1409-Pos B oard B11 INVESTIGATION OF STRUCTURAL DYNAMICS OF THE KCNE3 IN A LIPID BILAYER MEMBRANE USING SITE-DIRECTED SPIN LABELING EPR SPEC- TROSCOPY. William D. Carbo , Matthew Scheyer, Alberto Perez, Samuel Haralu, Gary A. Lorigan, Indra D. Sahu 1410-Pos B oard B12 THEORETICAL STUDY OF THE INTRINSIC CONFORMATIONAL PREFERENC- ES AND MICROSOLVATION EFFECT ON THE SELF-ASSEMBLY OF HYDRO- PHOBIC L-DIPEPTIDES. Francisco Adasme Carreno , Julio Caballero, Joel Ireta 1411-Pos B oard B13 MAPPING AMINO ACIDS AT PROTEIN-MEMBRANE INTERFACES TO UPDATE THE CURRENT MEMBRANE BINDING MODEL. Thibault Tubiana , Nathalie Reuter

1412-Pos B oard B14 ROLE OF GLYCOSYLATION IN LIPID-INTERACTING PROPERTIES OF PULMOSAPOSIN A, FROM THE PULMONARY SURFACTANT PROTEIN B PRECURSOR. Miriam Isasi , Jesús Pérez Gil, Lucía García 1413-Pos B oard B15 EXPLORING THE STRUCTURAL STABILITY AND ASSEMBLY MECHANISM OF HYDROPHOBIN PROTEINS. Kathleen L. Vergunst 1414-Pos B oard B16 UNDERSTANDING THE PACKING OF AMYLOIDOGENIC PEPTIDE SEG- MENTS USING ELECTRONIC STRUCTURE CALCULATIONS. Camila Munoz Gutierrez , Jans Alzate Morales, Joel Ireta 1415-Pos B oard B17 EFFECT OF RESIDUE SUBSTITUTIONS ON THE HYDROPHOBIC CORE OF THE C-TERMINUS OF THE PRION PROTEIN. Steffany Nguyen , Garrett M. Gloeb, Dan Irwin, Patricia Soto 1416-Pos B oard B18 INVESTIGATING ATOMIC LEVEL STRUCTURE IN PYRIFORM SILK PRO- TEINS. Jeffrey R. Simmons , Genevieve Gasmi-Seabrook, Jan K. Rainey 1417-Pos B oard B19 DECIPHERING THE CONFORMATIONAL DYNAMICS OF ESCHERICHIA COLI TYPE IV PILUS. Yasaman Karami , Olivera Francetic, Nadia Izadi Pruneyre, Michael Nilges 1418-Pos B oard B20 FILAMENTS UNDER FORCE: A COMPUTATIONAL MOLECULAR-SCALE INVESTIGATION OF TYPE IV PILI FROMMULTIPLE ORGANISMS. Bryan Bogin, Maria Fairfield, Rebecca B. Goncalves, Kimberly Jarquin, Stephen Jones, Christopher A. Lovenduski, Kevin Marin, Emma Webb, Horacio Vargas-Guzman, Adolfo Poma, Nicolas Biais, Joseph L. Baker 1419-Pos B oard B21 SEQUENCE-DEPENDENT ANALYSIS OF COLLAGEN MECHANICS. Alaa Al-Shaer , Aaron Lyons, Yoshihiro Ishikawa, Billy G. Hudson, Sergei P. Boudko, Nancy R. Forde 1420-Pos B oard B22 CALCIUM-INDUCED CONFORMATIONAL DYNAMICS OF THE C-DOMAIN OF TETRAHYMENA CYTOSKELETAL PROTEIN TCB2. Armaan Kumar , Adina M. Kilpatrick, Patricia Soto 1421-Pos B oard B23 A PARALLEL RATCHET-STROKE MECHANISM LEADS TO AN OPTIMUM FORCE FOR MOLECULAR MOTOR FUNCTION. Upasana L. Mallimadugula , Eric A. Galburt 1422-Pos B oard B24 DYNEIN ADAPTORS SUCH AS DROSOPHILA BICAUDAL ( DM BICD) RECOG- NIZE CARGO AND ARE REQUIRED TO ACTIVATE DYNEIN FOR PROCESSIVE TRANSPORT. Heying Cui , M. Yusuf Ali, Puja Goyal, Kaiqi Zhang, Jia Ying Loh, Kathleen M. Trybus, Sozanne R. Solmaz 1423-Pos B oard B25 STRUCTURAL ANALYSIS OF SMALL G-PROTEIN RAS MULTIMER INDUCED BY CHEMICAL MODIFICATION OF HVR DOMAIN WITH CAGED COM- POUND. Rufiat Nahar 1424-Pos B oard B26 ROLE OF THE TRP169 RESIDUE IN NEURONAL CALCIUM SENSOR DREAM. Maria D Santiago , Jaroslava Miksovska 1425-Pos B oard B27 THE INVISIBLE PROTEIN STATES OF MDMX AND MDM2 DETERMINE LIGAND-BINDING AFFINITY REVEALED BY CRYSTALLOGRAPHIC STRUC- TURES AND NMR DYNAMICS. Xiyao Cheng, Huili Liu, Yongqi Huang, Zhengding Su

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