Biophysical Society 67th Annual Meeting Program Guide

979-pos Board B108 INVESTIGATING THE SEQUENCE PROPERTIES THAT GOVERN DISORDER AND SECRETION OF BACTERIAL VIRULENCE PROTEINS. Cedrick Mukinay , Michael Baxa, Tobin R. Sosnick, Patricia L. Clark 980-pos Board B109 UNCOVERING THE MOLECULAR GRAMMAR OF IDPS IN DESICCATION TOLERANCE. Sourav Biswas , Feng Yu, Shahar Sukenik, Alex S. Holehouse, Thomas C. Boothby 981-pos Board B110 Travel Award Winner SUBSTITUTIONS AT NON-CONSERVED, RHEOSTAT POSITIONS IN IN TRINSICALLY DISORDERED REGIONS OF CIITA MODULATE ITS FUNC TION. Shwetha Sreenivasan 982-pos Board B111 INTERPRETING TRANSIENT INTERACTIONS IN INTRINSICALLY DISOR DERED PROTEINS. Samuel Wohl , Wenwei Zheng 983-pos Board B112 MOLECULAR MECHANISM OF PH-DEPENDENT MODULATION OF SUP35 PHASE SEPARATION BY INTRINSICALLY DISORDERED M DOMAIN. Jeffre H. Allen , Allison M. Whited, Loren E. Hough 984-pos Board B113 FUNCTIONAL SYNERGY BETWEEN DISORDERED PROTEINS AND SUGARS IN DESICCATION PROTECTION. Shraddha KC , Kenny Nguyen, Hugo Tapia, Thomas C. Boothby 985-pos Board B114 ENTROPY-ENTHALPY INTERPLAY IN ALUMINUM BOUND NEUROFILA MENTS. David Silva-Brea , David de Sancho, Xabier Lopez 986-pos Board B115 COMBINING SIMULATIONS AND SINGLE-MOLECULE FLUORESCENCE SPECTROSCOPY TO UNDERSTAND SARS-COV-2 NUCLEOCAPSID PROTEIN RNA INTERACTION. Jhullian J. Alston , Jasmine Cubuk, Jeremias Incicco, Melissa D. Stuchell-Brereton, Kathleen B. Hall, Alex S. Holehouse, Andrea Board B116 STRUCTURAL CHARACTERIZATION OF THE RNA POLYMERASE II CTD IN DIFFERENT PHOSPHORYLATION STATES. Wei Chen , Oluwadamilare Aboyewa, Scott A. Showalter 988-pos Board B117 INHIBITION OF CROSS-AMYLOID AGGREGATION OF AMYLOID-BETA AND ISLET AMYLOID PEPTIDE STUDIED BY MOLECULAR DYNAMICS SIMULA TION. Amit Srivastava , Kenana A. Adem, Sungmun Lee, Dirar M. Homouz 989-pos Board B118 ALLOSTERIC AND SUBSTRATE SITE EFFECTS OF RELEVANT AMINO ACIDS ON STRUCTURAL STABILITY AND FLEXIBILITY OF GLUTAMATE DEHYDRO GENASE-1 (GDH-1). Bogumil Zelent , David F. Wilson, Franz M. Matsch inky 990-pos Board B119 PH-DEPENDENT AGGREGATION OF THE PMEL17 REPEAT DOMAIN CHAR ACTERIZED BY NMR. Daniel L. Morris , Dexter N. Dean, Jared Shadish, Jennifer C. Lee, Nico Tjandra 991-pos Board B120 Travel Award Winner SENSITIVITY OR SPECIFICITY IN PROTEIN INTERACTIONS ARE INDEPEN DENTLY REGULATED UPON RECOGNITION: AN SH2 CASE STUDY. Gabriella Gerlach , Carlos J. Camacho 992-pos Board B121 A NOVEL INFRARED SPECTROSCOPIC APPROACH TO STUDY THE INTERAC TION OF AMYLOID-Β WITH CELL-PENETRATING PEPTIDES - A POSSIBLE NEW CLASS OF DRUGS TO COMBAT ALZHEIMER’S DISEASE. Suman Paul , Artem Danilov, Tobias Gokus, Andreas Barth Soranno 987-pos

993-pos Board B122 T-CELL IMMUNOGLOBULIN AND MUCIN-DOMAIN CONTAINING PROTEIN (TIM) STRUCTURAL DYNAMICS REVEALED BY MOLECULAR DYNAMICS SIMULATIONS. Mia A. Rosenfeld , Fiona L. Kearns, Joan Chongsaritsinsuk, Alexandra Steigmeyer, Kiera E. Mahoney, Taryn Lucas, Deniz Ince, Alexan dria Battison, Marie A. Hollenhorst, D. Judy Shon, Victor Attah, Catherine Kwon, Carolyn R. Bertozzi, Stacy A. Malaker, Rommie E. Amaro 994-pos Board B123 COMPLEXES OF CHARGED DISORDERED POLYELECTROLYTE-LIKE PRO TEINS: FROM THERMODYNAMICS TO STUCTURAL PLASTICITY. Aritra Chowdhury , Andrea Sottini, Alessandro Borgia, Madeleine B. Borgia, Souradeep Ghosh, Soumik Mitra, Tianjin Yang, Nicola Galvanetto, Rohan Eapen, Paweł Łukijańczuk, Ruijing Zhu, Daniel Nettels, Arindam Kundag rami, Benjamin Schuler 995-pos Board B124 IDPCONFORMERGENERATOR: A FLEXIBLE SOFTWARE SUITE FOR SAMPLING THE CONFORMATIONAL SPACE OF DISORDERED PROTEIN STATES. João M.C. Teixeira, Zi Hao Liu , Ashley Namini, Jie Li, Robert M. Vernon, Mickaël Krzeminski, Alaa A. Shamandy, Oufan Zhang, Mojtaba Haghighatlari, Lei Yu, Teresa L. Head-Gordon, Julie D. Forman-Kay 996-pos Board B125 MODELING THE MECHANISMS THROUGH WHICH PROTEIN PHASE SEPARATION INDUCES MEMBRANE CURVATURE. Ketsia Zinga , Jeanne C. Stachowiak, Pengyu Ren 997-pos Board B126 EFFECTS OF CHARGE RESIDUES ON Α-SYNUCLEIN FIBRIL FORMA TION. Emilios K. Dimitriadis , Ryan P. McGlinchey, Jennifer C. Lee 998-pos Board B127 PHASE SEPARATION UNDERLIES INTERACTIONS OF THE SARS-COV-2 NUCLEOCAPSID PROTEIN WITH NUCLEOLI. Priyanka Dogra , Hazheen Shirnekhi, Mylene C. Ferrolino, Michele Tolbert, Cheon-Gil Park, Richard W. Kriwacki 999-pos Board B128 PARTIAL MIMICRY OF THE MICROTUBULE BINDING OF TAU BY ITS MEM BRANE BINDING. MatthewMacAinsh , Huan-Xiang Zhou Condensates: Physical Properties and Modeling II (Boards B129 - B149) 1000-pos Board B129 SALT DOPING OF HYALURONIC ACID GLYCOPOLYMER BIOCONDEN SATES. James D. Sterling , Lu Fu, Kenisha Pudun, Shenda Baker, Megan Lord 1001-pos Board B130 EFFECTS OF CROWDERS ON PHASE SEPARATION OF ASSOCIATIVE MACROMOLECULES. Gaurav Chauhan , Anne Bremer, Furqan Dar, Tanja Mittag, Rohit V. Pappu 1002-pos Board B131 MODIFIED ROUSE-ZIMM THEORY FOR COMPUTING SEQUENCE-SPECIFIC VISCOELASTIC PROPERTIES OF BIOMOLECULAR CONDENSATES. Samuel R. Cohen , Ibraheem Alshareedah, Wade M. Borcherds, Mina Farag, Tanja Mittag, Priya R. Banerjee, Rohit V. Pappu 1003-pos Board B132 QUANTITATIVE ANALYSIS OF INTRACELLULAR PROTEIN PHASE TRANSI TIONS. Ammon E. Posey , Rohit V. Pappu 1004-pos Board B133 PHASE BEHAVIOR OF 1-RIBBON AND 2-RIBBON FIBRIL SELF-ASSEMBLY IN A SIMPLE NETWORK HAMILTONIAN MODEL OF PROTEIN FIBRILLIZA TION. Elizabeth M. Diessner , Loring J. Thomas, Carter T. Butts

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