Biophysical Society 67th Annual Meeting Program Guide

Careers in Industry: A Q&A Panel 1:00 pm - 2:30 pm, Room 8

Snack Break 1:45 pm - 3:00 pm, Exhibit Hall BC Poster Presentations and Late Posters 1:45 pm - 3:45 pm, Exhibit Hall BC Overview of NIGMS/NIH Funding Programs Available to Biophysical Society Investigators 2:00 pm - 3:00 pm, Room 6E The National Institute of General Medical Sciences (NIGMS) at the NIH offers an array of funding programs to investigators at all career stages. NIGMS staff will provide an overview of these programs, highlighting opportunities of particular interest to the Biophysical Society community. The overview will be followed by an in-depth presentation of the “ Maxi mizing Investigators Research Award (MIRA, R35)” funding program . Since 2016, the NIGMS has been funding individual laboratory research programs that are within the NIGMS scientific mission through the MIRA program. The program aims to increase the efficiency of funding for investigators; decrease the administrative burden of grant application, review, and management; allow flexibility of future research directions in an investigator’s laboratory; maintain a more stable research environ ment; and enhance the opportunities for breakthrough discoveries. The MIRA program includes two companion funding opportunity announce ments (FOAs), one for Early-Stage Investigators (PAR-20-117) and the other for Established Investigators and New Investigators (PAR-22-180). NIGMS staff will discuss the key features of the MIRA FOAs and answer questions about MIRA funding. If you are an Established Investigator holding an eligible NIGMS award (a single-PI R01, R35, R37, DP1, DP2, SC1, NRMN U01), or if you are an Early-Stage Investigator or a New Inves tigator performing research within the NIGMS mission, you are encour aged to attend this session. Presenters Dorothy Beckett, Director, Division of Biophysics, Biomedical Technology, and Computational Biosciences Zhongzhen Nie, Chief, Pharmacological and Physiological Sciences Branch, PPBC, NIGMS Career Development Center Workshop The Strategic Postdoc: How to Find and Leverage Your Postdoc Experience 2:30 pm - 3:30 pm, Room 16B Many PhDs just kind of fall into a postdoc, rather than thinking about it from a strategic perspective. Your postdoc is never an end in itself; rather it’s a means to another end whether that goal is a faculty position at a research university, a small college, national lab, or perhaps an industry job. Learn how to find postdoc opportunities that will best prepare you for that next step, and how to use your postdoc experience to facilitate the transition to the next step in your career. Education Committee Meeting 3:00 pm - 5:00 pm, Room 14B Biophysical Reports Editorial Board Meeting 3:30 pm - 5:30 pm, Room 14A

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Join us for a Q&A discussion about scientific careers in industry. Industry panelists will answer audience questions and share their career experi ences. Hear from professionals in different roles and positions and get tangible advice for identifying and pursuing a career in industry. Chair Erin Dueber, Genentech, CA, USA Speakers Speakers to be announced. The Biophysicist Editorial Board Meeting 1:00 pm - 3:00 pm, Room 14A Exhibitor Presentation Delmic 1:30 pm - 3:00 pm, Room 9 Streamline the Cryo-ET Workflow and Get More Useful Biological Insights with Delmic’s METEOR and CERES Systems Cryo-ET is a powerful imaging technique that allows protein complexes in their near-native cellular environment to be resolved at a nanome tre resolution. Unfortunately the uptake of this powerful technique is hampered by its current error prone workflow, which often results in damaged, contaminated, and devitrified samples that cannot be used for data analysis. At Delmic we developed a host of technologies to unleash cryo-ET’s full potential. We will present METEOR, a fluorescent light microscope that is directly integrated into a cryo-FIB/SEM. It allows the user to skip unnecessary transfer steps and therefore decrease ice contamination. The presence of the targeted fluorescent signal in the lamellae can be checked during and after the milling process and cryo-CLEM data quality is improved. METEOR can therefore dramatically increase cryo-ET sample yield. We will also present the CERES Ice Defence System, which increases sample throughput and quality by minimizing ice contamination through out the cryo-ET sample preparation workflow. We will show that the samples can be prepared contamination free in the CERES Clean Station, a dedicated and moisture free workstation for cryo-ET sample prepara tion. From this workstation the samples can be transferred to the cryo FIB/SEM using the CERES Vitri-Lock providing a high vacuum, anhydrous environment. In the FIB/SEM the sample is protected by the CERES Ice Shield, which protects against amorphous ice build-up on the sample. This protection is crucial for high cryo-ET data quality and allows long automated milling sessions. Delmic’s cryo solutions allow researchers to obtain better quality cryo-ET results, higher throughput, and higher resolution. Speaker Marit Smeets, Product Manager, Delmic

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Meet the Editors, Biophysical Journal 1:45 pm - 3:00 pm, Lobby BC/Publications Booth

Take this opportunity to meet editors of Biophysical Journal . Editors will be available to talk about the journal and answer questions about where you should submit your work, what will help to get your work published, and what you can expect when you submit. Editor-in-Chief Vasanthi Jayaraman and other editors will be present at the Biophysical Society publications booth.

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