Biophysical Society 67th Annual Meeting Program Guide

Wednesday, February 22, 2023

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Daily Program Summary All rooms are located in the San Diego Convention Center unless noted otherwise.

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8:00 am-11:00 am New Council Meeting 8:00 am-3:00 pm Poster Viewing

Room 17B

Exhibit Hall BC

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Symposium: Biophysics of Mitosis

Room 6A

Chair Mary Elting, North Carolina State University, USA ACTION AT A DISTANCE ALONG THE MICROTUBULE COUPLES KINESIN MOTORS. Meredith Betterton NAEGLERIA ’S MITOTIC SPINDLES ARE BUILT FROM UNIQUE TUBULINS AND ASSOCIATED MICROTUBULE BINDING PRO TEINS. Lillian Fritz-Laylin BUILDING THE CYTOKINETIC RING: FROMMOLECULAR MECHANISMS TO CELLULAR FUNCTION. Dimitrios Vavylonis DESTRUCTIVE TESTING ON MITOTIC MACHINERY: PROBING THE MECHANICS OF FISSION YEAST CELL DIVISION BY LASER ABLATION. Mary W. Elting

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8:15 am-10:15 am

Symposium: Mechanotransduction Complex in Hair Cells Chair Robert Fettiplace, University of Wisconsin–Madison, USA

Room 6B

TOWARDS AN ATOMISTIC MODEL OF THE VERTEBRATE INNER-EAR TRANSDUCTION APPARATUS. Marcos Sotomayor FUNCTION AND REGULATION OF TMC1, LHFPL5, AND TMIE IN AUDITORY MECHANOTRANSDUCTION COMPLEX. Pingbo Huang REGULATION OF MEMBRANE HOMEOSTASIS BY TMC1 MECHANOELECTRICAL TRANSDUCTION CHANNELS. Angela Balles teros Morcillo THE CONDUCTANCE OF TMC1-CONTAINING MECHANOTRANSDUCER CHANNELS AND THE ROLES OF LHFPL5 AND TMIE IN COCHLEAR HAIR CELLS. Robert Fettiplace

8:15 am-10:15 am

8:15 am-10:15 am Platform: Condensates in Physiology and Disease 8:15 am-10:15 am Platform: RNA Structure and Dynamics 8:15 am-10:15 am Platform: Protein Dynamics and Allostery II 8:15 am-10:15 am Platform: Membrane Protein Structures 8:15 am-10:15 am Platform: Protein-Lipid Interactions: Structures 8:15 am-10:15 am Platform: Optical Microscopy and Superresolution Imaging III

Room 6C Room 6D Room 6E Room 6F Room 5AB Room 11AB

10:30 am-12:30 pm Poster Presentations and Late Posters

Exhibit Hall BC

Symposium: Mechanisms of Membrane Insertion

Room 6A

Chair Bil Clemons, California Institute of Technology, USA THE BACTERIAL SECRETOSOME FOR BACTERIAL ENVELOPE BIOGENESIS. Ian Collinson CRYO-EM AND PHOTOCROSSLINKING STUDIES REVEAL THE MECHANISM OF MITOCHONDRIAL PROTEIN IMPORT BY THE TIM COMPLEX. Eunyong Park BIOGENESIS OF MITOCHONDRIAL OUTER MEMBRANE PROTEINS. Rebecca Voorhees A STRUCTURALLY DERIVED UNIVERSAL MECHANISM FOR THE CATALYTIC CYCLE OF THE TAIL-ANCHORED TARGETING FAC TOR GET3. Bil Clemons

1:00 pm-3:00 pm

Symposium: Fuzzy Complexes

Room 6B

Chair Benjamin Schuler, University of Zurich, Switzerland EVOLUTION OF EUKARYOTIC TRANSCRIPTIONAL ACTIVATION DOMAINS. Max V. Staller

1:00 pm-3:00 pm

INTRINSIC DISORDER IN THE HIGHLY ORDERED CIRCADIAN CLOCK: A TALE OF TWO ISOFORMS. Jennifer M. Hurley A MODEL SYSTEM REVEALS HOW DIFFERENT LINKER HISTONES DIRECT CHROMATIN TO LIQUID-LIKE OR FIBRE-LIKE CON DENSED STATES. Katherine Stott INTERACTION DYNAMICS OF DISORDERED PROTEINS FROM SINGLE-MOLECULE SPECTROSCOPY. Benjamin Schuler

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