Biophysical Society 67th Annual Meeting Program Guide

Jesse J. Howe, Oregon State University 1694 -Pos , Board B99 MULTIVALENCY IN 53BP1-LC8 INTERACTIONS SUGGEST NEW BINDING MODE IN LC8 INTERACTIONS Jessica I. Kelz, University of California, Irvine 1448 -Plat IMPLEMENTATIONOF SPECIFICATIONS GRADING INANUPPER-DIVISION CHEMICAL BIOLOGY COURSE David King, The Ohio State University 1506 -Plat NANOSCALE REMODELING OF SODIUM CHANNELS IN THE CARDIAC TRANSVERSE TUBULES CONTRIBUTES TO ABERRANT CALCIUM RELEASE IN A SCN1A HAPLOINSUFFICIENT MOUSE Robert C. Klipp, University of Colorado Anschutz Medical 1919 -Pos , Board B324 MECHANISTIC INSIGHTS INTO LIPID REGULATION OF THE ACID-SENSING ION CHANNELS Maicon Landim-Vieira, Florida State University 1950 -Pos , Board B355 DISSECTING THE MECHANISMS BY WHICH A PATHOGENIC VARIANT IN CARDIAC TNT TAIL DOMAIN LEADS TO DISTURBED MYOFILAMENT PERFORMANCE Isabella Leite Coscarella, Florida State University 1969 -Pos , Board B374 HCM AND DCM ASSOCIATED TNNT2 SARCOMERIC VARIANTS INDUCE CRYO-EM STRUCTURES OF THE D290V VARIANT OF THE HNRNPA2 LOW COMPLEXITYDOMAINREVEAL THEMECHANISMOF ITSPATHOGENICITY Alberto Marin-Gonzalez, Johns Hopkins University 1490 -Plat MULTIPLEXING CAS9 ACTIVITY WITH MULTI-TARGET CRISPR Jordan McIvor, The University of Auckland 1680 -Pos , Board B85 Publishing Title:
PHOSPHORYLATION REFINES THE CONTROL OF COMPLEX FORMATION IN IDPS Louisa Mezache, The Ohio State University 2111 -Pos , Board B516 SARS-COV-2 SPIKE PROTEIN-INDUCED INFLAMMATION UNDERLIES PROARRHYTHMIA IN COVID-19 Alina Milici, KU Leuven 1906 -Pos , Board B311 SILICA NANOPARTICLES INHIBIT RESPONSES TO ATP IN HUMAN AIRWAY EPITHELIAL 16HBE CELLS Hossein Moghimianavval, University of Michigan 2022 -Pos , Board B427 A SYNTHETIC BIOLOGY TOOL FOR CONTACT-DEPENDENT SYNTHETIC CELL COMMUNICATION NUCLEUS REMODELING IN HUMAN IPSC-CMS Jiahui Lu, University of California Los Angeles 1522 -Plat

Éva Moussong, Eötvös Loránd University 1618 -Pos , Board B23 EFFECT OF NANOPARTICLES ON THE AGGREGATION AND AMYLOID FORMATION OF AMYLOID-BETA PEPTIDE Florence D. Mumbi, Florida State University 1964 -Pos , Board B369 INVESTIGATING THE SARCOLEMMA-SARCOMERE CONNECTION AND

FORCE TRANSMISSION IN THE HEART Haibo Ni, University of California, Davis 1857 -Pos , Board B262

3D SPATIAL MODELING OF SINOATRIAL NODE CELLS REVEALS A CRITICAL ROLE OF SUBCELLULAR RYANODINE RECEPTOR DISTRIBUTION IN PACEMAKER AUTOMATICITY Crystal F. Ottoway, Arizona State University 1519 -Plat PHOTO-INDUCED ELECTRON TRANSFER BETWEEN TRYPTOPHAN AND CYSTEINE: PH DEPENDENCE Simone Pelizzari, Medical University of Innsbruck 1835 -Pos , Board B240 IDENTIFYING THE CA V 1 1 VOLTAGE-SENSING DOMAINS INVOLVED IN CHANNEL GATING AND EXCITATION CONTRACTION COUPLING Aida Rahimi Kahmini, Florida State University 1855 -Pos , Board B260 COMPENSATORY CALCIUM HANDLING MAY UNDERLIE INCREASED ARRHYTHMIA SUSCEPTIBILITY OF SARCOSPAN-DEFICIENT MICE AFTER ISCHEMIA-REPERFUSION INJURY Faye Raymond, University at Buffalo 1925 -Pos , Board B330 KINETIC MECHANISM OF NMDA RECEPTOR INHIBITION BY THE KETAMINE METABOLITE 2R,6R-HYDROXYNORKETAMINE Bakai Sheyitov, Emory University 2123 -Pos , Board B528 INVESTIGATING OPTIMAL KINETIC PARAMETERS OF EXONUCLEASE III TO CREATE A NEXT-GENERATION, ROBUST, SELF-AVOIDING ROLLING MOTOR BIOSENSOR Charlotte Smith, University of California, Davis 1851 -Pos , Board B256 SEX DIFFERENCES IN ELECTROPHYSIOLOGY OF THE INTACT ATRIA Justyna B. Startek, KU Leuven 1562 -Plat A TR(I)P THROUGH TRPA1 MECHANOSENSITIVITY Daniel G P Turner, University of Wisconsin - Madison 2009 -Pos , Board B414 ENGINEERED CARDIAC TISSUE AS A NOVEL IN VITRO HUMAN MYOCARDIUM MODEL FOR STUDYING CARDIAC STRETCH Daiana C.O. Vieira, University of Maryland 1507 -Plat INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES ENABLE THE DEVELOPMENT OF NEW THERAPEUTIC STRATEGIES FOR THE TREATMENT OF LQT8

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