Biophysical Society 67th Annual Meeting Program Guide

Single-Molecule Forces, Manipulation, and Visualization Symposium 1:30 pm - 5:30 pm, Room 11AB Subgroup Co-Chairs Zev Bryant, Stanford University, USA Wesley Wong, Harvard University, USA No Abstract 1:30 pm REALTIME OBSERVATION OF SUBSTRATE TRANSLOCATION DYNAMICS IN AN ABC TRANSPORTER. Ruben Gonzalez No Abstract 1:52 pm TETHER-FREE, SINGLE-MOLECULE MICROSCOPY OF DNA INTERACTIONS IN OUT-OF-EQUILIBRIUM CONDITIONS. Sabrina Leslie No Abstract 2:14 pm THE MECHANICAL ACTIVATION OF TALIN- AND VINCULIN-MEDIATED RIGIDITY SENSING OF EXTRACELLULAR MATRIX. Jie Yan No Abstract 2:36 pm HOW SOME SINGLE RECEPTOR-LIGAND BONDS LOCK INSTANTLY INTO A LONG-LIVED FORCE-RESISTANT STATE. Wendy Thomas No Abstract 2:58 pm ORIGAMI MOVEMENT MICROSCOPY. Pallav Kosuri 3:20 pm break No Abstract 3:30 pm TRAPPED FOR LIFE: MY CAREER, ONE MOLECULE AT A TIME. Steven Block No Abstract 4:14 pm UNIVERSALITY VS. SPECIFICITY IN SYNAPTIC TRANSMISSION. Olga Dudko No Abstract 4:36 pm RNA COLD MISFOLDING. Felix Ritort No Abstract 4:58 pm DNA LOOP EXTRUSION IS A CONSERVED MECHANISM AMONG ALL EUKARYOTIC SMC COMPLEXES. Eugene Kim 5:20 pm closing remarks and subgroup business meeting Career Development Center Workshop Leveraging LinkedIn in the PhD Job Search: Networking, Informational Interviews, and More 3:00 pm - 4:00 pm, Room 16B You’ve done some exploration and identified some interesting possibili ties as the next step after grad school or your postdoc, but is it enough to convince you that research in industry, medical science liaison, data science, etc. is right for you? More importantly, do you know enough to craft a persuasive story about why you’re a credible and compelling candidate? This presentation provides specific examples of how you build out your knowledge of a new, potential career field, and forge valuable connections that can facilitate your successful transition out of academia using LinkedIn, professional societies, informational interviews, and more.

No Abstract 4:30 pm ORIGIN OF PULSED ACTOMYOSIN CONTRACTIONS AND THEIR ROLE IN CELL SHAPE CONTROL. Shiladitya Banerjee No Abstract 4:50 pm ULTRA-RAPID MICROTUBULE DEPOLYMERISATION BY THE COMMON ANCESTOR OF THE KINESIN-13 FAMILY. Claire Friel 28-Subg 5:10 pm DECIPHERING THE MECHANICS OF MICROTUBULE BUNDLES IN MITOSIS. Scott Forth Multiscale Genome Organization Symposium 1:30 pm - 5:30 pm, Room 7AB Subgroup Co-Chairs Yamini Dalal, NIH, USA Anna Panchenko, Queen’s University, Canada Program Co-Chairs Alexei Onufriev, Virginia Tech, USA Bin Zhang, Massachusetts Institute of Technology, USA 1:30 pm opening remarks No Abstract 1:35 pm FOLDING CHROMOSOMES WITHOUT KNOTTING THEM. Job Dekker No Abstract 2:05 pm CHARACTERIZING THE VARIABILITY AND ORGANIZING PRINCIPLES OF WHOLE GENOME STRUCTURES BY MULTI-MODAL DATA INTEGRATION. Frank Alber 29-Subg 2:30 pm MECHANICAL FRUSTRATION OF PHASE SEPARATION IN THE CELL NUCLE US BY CHROMATIN. Yaojun Zhang , Daniel S. Lee, Yigal Meir, Clifford P. Brangwynne, Ned S. Wingreen 2:55 pm student/postdoc talk 3:10 pm best poster award ceremony No Abstract 3:30 pm THE 3D GENOME ARCHITECTURE IN HUMAN MALARIA VECTORS. Igor Sharakhov No Abstract 3:55 pm PHASE TRANSITIONS IN THE NUCLEUS OF CELLS SHAPE CHROMATIN FOLDING. Mario Nicodemi No Abstract 4:20 pm TRANSCRIPTIONAL CONTROL BY LOW-COMPLEXITY DOMAIN INTERAC TIONS: A SINGLE-MOLECULE PERSPECTIVE. Shasha Chong No Abstract 4:45 pm CHANGING STRUCTURES OF CHROMOSOMES DURING A CELL CYCLE: ROLE OF MULTIPLE MOTORS. Dave Thirumalai 5:15 pm closing remarks 5:20 pm subgroup business meeting

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