Biophysical Society 67th Annual Meeting Program Guide

558-pos Board B379 STRETCH ACTIVATED FORCE PRODUCTION INCREASES DURING FATIGUE IN FAST-CONTRACTING SKELETAL MUSCLE FIBERS. Philip Woods , Douglas M. Swank, Mark S. Miller 559-pos Board B380 SKELETAL MUSCLE FIBER FORCE DECLINES WITH CHRONIC KIDNEY DIS EASE IN JUVENILE AND ADULT MICE. Brent A. Momb , Edwin Patino, Oleh Akchurin, Mark S. Miller 560-pos Board B381 IRON SUPPLEMENTATION IMPROVES SKELETAL MUSCLE CONTRACTILE PROPERTIES IN MICE WITH CHRONIC KIDNEY DISEASE. Brent Momb , Edwin Patino, Oleh Akchurin, Mark S. Miller 561-pos Board B382 PHARMACOLOGICAL INTERVENTIONS IMPROVE MYOSIN-ACTIN CROSS BRIDGE FUNCTION IN MICE WITH ADVANCED CHRONIC KIDNEY DIS EASE. Brent Momb , Edwin Patino, Oleh Akchurin, Mark S. Miller 562-pos Board B383 EMBRYONIC MYOSIN MUTATIONS ALTER THE MECHANICS AND MATU RATION OF HIPSC DERIVED SKELETAL MUSCLE. Christian J. Mandrycky , Saffie Mohran, Matthew C. Childers, Shawn M. Luttrell, Kati Buckingham, Michael J. Bamshad, David L. Mack, Michael Regnier 563-pos Board B384 PASSIVE FORCE ENHANCEMENT IS NOT ABOLISHED BY SHORTENING OF SINGLE FIBRES. Shuyue Liu , Heron Baptista de Oliveira Medeiros, Heiliane de Brito Fontana, Walter Herzog 564-pos Board B385 IMMUNOGLOBULIN DOMAIN UNFOLDING AND REFOLDING IN PASSIVELY STRETCHED MYOFIBRILS. Chris Tiessen , Tim Leonard, Gudrun Schappach er-Tilp, Walter Herzog 565-pos Board B386 DIFFERENT PHOSPHORYLATION STATES OF NATIVE TITIN FILAMENTS VISUALIZED BY ATOMIC FORCE MIVROSCOPY. Andrea Balogh-Molnar, Dominik Sziklai, Miklos Kellermayer, Zsolt Martonfalvi 566-pos Board B387 DO ACTIN-MYOSIN CROSS-BRIDGES EXHIBIT A VISCOELASTIC BEHAV IOUR? Venus Joumaa , Wejdaan Faridi, Shuyue Liu, Walter Herzog 567-pos Board B388 MEASURING SARCOMERE DYNAMICS FOLLOWING IMMUNOFLUORES CENT LABELLING OF CONSTITUTIVE STRUCTURAL AND CONTRACTILE PROTEINS. Armaan Sekhon , Dhairya Desai, Tim Leonard, Walter Herzog 568-pos Board B389 MODELING SPATIAL INHOMOGENEITIES IN A CROSSBRIDGE ENSEMBLE REVEALS WHERE MEAN-FIELD ESTIMATES OF SARCOMERE STIFFNESS BREAK DOWN. Dan Rivera , Madhusudhan Venkadesan 569-pos Board B390 EFFECTS OF BLEBBISTATIN ON FORCE PRODUCTION, ACTIN MOTILITY AND THE FORCE-VELOCITY RELATION PRODUCED BY MYOSIN II FILA MENTS AND MYOFIBRILS. Yu-Shu Cheng , Daren Elkrief, Dilson E. Rassier 570-pos Board B391 Travel Award Winner A RATIONAL APPROACH TO SELECTIVE TARGETING OF SKELETAL MYO SIN. Anna Katarina Antonovic , Julien Ochala, Arianna Fornili 571-pos Board B392 KINETICS OF INTERACTION OF MYOSIN-NUCLEOTIDE COMPLEX AND ACTIN. Aarushi Naskar, Yuri Nesmelov 572-pos Board B393 REGULATION OF TROPONIN AND MYOSIN CONFORMATION IN THIN- AND THICK-FILAMENT DOMAINS IN THE SARCOMERE OF SKELETAL MUSCLE MYOFIBRILS. Kristina Sliogeryte, Luca Fusi

573-pos Board B394 INTERPRETING EQUATORIAL X-RAY DIFFRACTION PATTERNS FROM STRI ATED MUSCLE WITH MULTISCALE MODELING. Momcilo Prodanovic, Yiwei Wang, Srboljub M. Mijailovich, Thomas C. Irving 574-pos Board B395 CRYO-EM STRUCTURE OF TARANTULA MYOSIN FILAMENT: IMPLICATIONS FOR ANALYSIS OF MYOPATHY MUTATIONS. Debabrata Dutta , Vu Nguyen, Raul Padron, Roger Craig 575-pos Board B396 CHEMOMECHANICAL ENERGY REGULATES TIME-DEPENDENT CHANGES IN THIN FILAMENT ACTIVATION. Henry G. Zot , Javier E. Hasbun 576-pos Board B397 EXAMINATION INTO PROTEIN ASSEMBLY WITHIN THE CARDIAC THIN FILAMENT: WHY THE TROPONIN COMPLEX CROSSES OVER. Anthony P. Baldo , Jil C. Tardiff, Steven D. Schwartz 577-pos Board B398 CONDITIONALLY DOMINANT NEGATIVE IMPACTS OF CLINICALLY RECES SIVE TNNT1 MYOPATHY MUTATIONS. Han-Zhong Feng , Jian-Ping Jin 578-pos Board B399 THERMOGENIC REGULATION OF THE SIMPLE HARMONIC MOTION OF TROPOMYOSIN BY WEAK-BINDING MYOSIN CROSS-BRIDGES EXPLAINS SPONTANEOUS OSCILLATORY CONTRACTIONS. James J. Earley Poster: Smooth Muscle and Cardia Muscle Board B400 ATRIAL CARDIOMYOCYTES FROM A CANINE MODEL OF ATRIAL FIBRIL LATION DEMONSTRATE REDUCED FORCE DEVELOPMENT AND ALTERED EXPRESSION OF CONTRACTILE PROTEINS. Hannah E. Cizauskas , Kelly Araujo, Seby Edassery, Jonathan A. Kirk, Rishi Arora, David Barefield 580-pos Board B401 CARDIAC MYOSIN’S MECHANICS AND LOAD DEPENDENT KINETICS ARE NOT ALTERED BY THE THIN-FILAMENT PROTEINS. Brent Scott , Sarah R. Clippinger, Samantha K. Barrick, William Stump, Thomas Blackwell, Michael J. Greenberg 581-pos Board B402 CALDESMON ENHANCES MOTILITY INHIBITION BY MYOSIN DEPHOS PHORYLATION. Matheus Schultz , Linda Kachmar, Gijs Ijpma, Anne-Marie Lauzon 582-pos Board B403 STRIATED MUSCLE MLCP IS REGULATED BY MYPT2 TO LIMIT BASELINE CARDIAC MYOSIN PHOSPHORYLATION. Eunyoung Lee, Zhenan Liu, Her man I. May, Thomas G. Gillette, Joseph A. Hill, Audrey N. Chang 583-pos Board B404 PHOSPHO-MIMETIC CARDIAC TROPONIN I SER43/45 PRODUCES EARLY CHANGES IN MITOCHONDRIA. Paige Reynolds, Oula Salih, Joseph Ruff, Sai H. Nagidi, Emily Lavey, Margaret V. Westfall 584-pos Board B405 TROPOMYOSIN R160A IS CRUCIAL FOR TNI PHOSPHORYLATION-INDUCED EFFECTS ON CALCIUM SENSITIVITY. Meaghan Barry , Michael J. Rynkie wicz, An-yue Tu, Michael Regnier, William Lehman, Jeffrey R. Moore 585-pos Board B406 MECHANISTIC STUDY OF MECHANICAL STRETCH INDUCED INCREASE IN CA 2+ SENSITIVITY OF TROPONIN C. Xutu Wang , Wenji Dong Regulation, Mechanics (Boards B400 - B418) 579-pos

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