Biophysical Society Bulletin | December 2018

Communities

Communities

Biological Fluorescence The Biological Fluorescence Subgroup will have its annual meeting on March 2, 2019, from 1:00 PM to 5:30 PM as part of the 63rd Annual Meeting of the Biophysical Society in Baltimore, MD. We have an exciting program this year with invited speakers Alessandra Cambi , Radboud University, The Netherlands; Luke Lavis , Janelia Research Campus, USA; Bin Wu , Johns Hopkins University, USA; Ralf Jungmann , Max Planck Institute of Biochemistry, Martinsried Germany; Don Lamb , Ludwig Maximilian University of Munich, Germany; and Elizabeth Hillman , Columbia University, USA. Our invited speakers will be presenting on a wide range of topics, includ- ing new fluorescence dyes, applications of superresolution fluorescence microscopy, 3D single-molecule tracking in living cells, rapid 3D fluorescence imaging in vivo, and other novel applications of fluorescence methodologies. The session will also feature rapid-fire poster highlight talks by promising young researchers in the field. We will conclude the subgroup session with the announcements and presentations for the Young Fluorescence Investigator Award and the Gregorio We- ber Award. Note that links to these awards with information on eligibility and nomination requirements can be found at the subgroup website at https:/www.biophysics.org/subgroups/ biological-fluorescence-1. December 31, 2018, is the deadline for nominations to be submitted. The subgroup session is open to any member of the Biophys- ical Society who is registered for the Annual Meeting; how- ever, we encourage you to join the subgroup through the Bio- physical Society website as membership fees are essential for paying for the costs of the venue and associated audiovisual fees. The link for membership is: https:/www.biophysics.org/ become-a-member and remember to select membership in the Biological Fluorescence subgroup during the process. We look forward to seeing you for our exciting Saturday after- noon session at the 63rd Annual Meeting in Baltimore. — Paul Wiseman , Chair Cell Biophysics Are you a biophysicist interested in probing the inner work- ing of cells? Are you a cell biologist longing for quantitative biophysical measurements of cellular processes? Or are you a physicist fascinated by the intricacy but overwhelmed by the complexity of cells? If any of these descriptions fits you, join the Cell Biophysics Subgroup to find like-minded colleagues. The Cell Biophysics Subgroup was established in 2018 to create a community just for you! The successful inaugural subgroup meeting was held this past February in San Francis- co, and our Second Annual Subgroup Symposium will be held

in Baltimore on the first day of the Annual Meeting, Saturday, March 2, 2019. A social networking event for subgroup mem- bers will follow the symposium. The symposium features a list of exciting topics including cell-environment interactions, cellular multi-resolution dynamics, systems cell biophysics, single-molecule manipu- lations in single cells, and more. Speakers include Haw Yang , Princeton University, USA; Kandice Tanner , National Institutes of Health, USA; Liedewij Laan , Delft University of Technology, The Netherlands; Christine Payne , Duke University, USA; Johan Elf , Uppsala University, Sweden; Jung-chi Liao , Academia Sinica IAMS, Taiwan; and David Rueda , Imperial College School of Medicine, UK. Additionally, the symposium will feature talks selected from abstracts submitted by subgroup members. We anticipate that the symposium will provide a platform for cell biophysicists to share scientific ideas, discuss research results, forge new collaborations, and together, push the frontiers of knowledge in cell biophysics. Every BPS member is welcome to attend the symposium. We do, however, ask you to please show your support by register- ing as a member of the subgroup. Your membership fees will allow us to cover the cost of the annual subgroup symposium and the fun social event that follows. Your commitment and continuous support are crucial to the success of the subgroup and the scientific community. Starting this year, one subgroup membership is includ- ed in your BPS dues; you can select to support additional subgroups for $20 each. So please join the Cell Biophysics Subgroup when you renew your BPS membership, when you register for the BPS meeting, or at any other time! Please visit https:/www.biophysics.org/subgroups/cell-biophysics. We look forward to seeing you in Baltimore! Jie Xiao , Chair (2018–2019) Julie Biteen , Chair-elect (2019–2020) David Rueda , Secretary-Treasurer (2019–2021) Exocytosis/Endocytosis The 2019 Exocytosis/Endocytosis Subgroup Symposium is scheduled for Saturday, March 2, at the Baltimore Convention Center as part of the 63rd Biophysical Society Annual Meeting in Baltimore, Maryland. The theme for this year’s symposium is, From Molecule to Mechanism: New Insights into the Dynamics of Vesicle Fusion and Recycling . Antoine van Oijen , Program Chair (2019) Keng-hui Lin , Program Chair-elect (2020)

Featured speakers are: Nils Brose , Max Planck Institute for Experimental Medicine. Dynamic Control of Vesicle Priming in Synaptic Short-term Plasticity Ira Milosevic , European Neuroscience Institute, Goettingen Regulation of Vesicle Acidification at the Neuronal Synapse Justin Taraska , National Heart, Lung, and Blood Institute/NIH Imaging the Nanoscale Structure of Endocytosis and Exocy- tosis with Light and Electron Microscopy In addition, several short talks from trainees will be select- ed from the abstracts submitted for the Annual Meeting. A closing banquet dinner will be held at Eat Bertha’s Mussels, 734 S. Broadway, Baltimore, and will allow for plenty of net- working and scientific interactions after the symposium. The organizers invite all members of the Biophysical Society to join us for what promises to be an outstanding day of cut- ting-edge science and comradery. — Amy Lee , Chair Intrinsically Disordered Proteins Proteins and protein regions that lack tertiary stability under normal conditions, known as intrinsically disordered proteins (IDPs), have diverse biological roles and are known to exert regulatory control over many key aspects of human develop- ment, aging, and disease. An example is the quality control shuttle proteins called ubiquilins. Like many IDPs, ubiquilins undergo liquid-liquid phase separation at physiological con- ditions. The Castañeda lab, Syracuse University, has shown that protein-protein interactions and disease mutations of ubiquiliins modulate phase separation in vitro and in vivo. Many groups are involved in efforts to determine the physical properties that control phase separation. For example, the Fawzi lab, Brown University, has shown recently that both disease-related mutations and post-translational modifica- tions affect the phase separation of hnRNPA2, a protein that helps to manage cell proliferation and differentiation. Addi- tionally, the Musselman lab, University of Iowa, has shown that the intrinsically disordered tail of the histone H3, import- ant for chromatin regulation, remains dynamic while interact- ing with nucleosomal DNA. 2019 Sir Bernard Katz Award Keynote Lecture Ed Chapman , University of Wisconsin/HHMI Diverse Functions of the Synaptotagmins

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If you are interested in the biophysics of intrinsically disor- dered proteins, please consider joining the IDP Subgroup as a member and attending the IDP Subgroup Symposium at the Annual Meeting in Baltimore. The subgroup symposium talks will be held on Saturday, March 2, and will present new results on the mechanisms that control liquid-liquid phase separation, fibril formation, and binding specificity involv- ing disordered proteins. If you are interested in joining the subgroup for dinner following the symposium, please contact Loren Hough (hough@colorado.edu) The IDP Subgroup Business Meeting will be held at 10:30 AM on March 2, preceding the subgroup symposium. If you would like to become involved in subgroup organization or leader- ship, please join us. We encourage all subgroup members to become involved in our community. — Loren Hough , Secretary-Treasurer — Steven Whitten , Secretary-Treasurer Elect Membrane Biophysics The 47th Annual Membrane Biophysics Subgroup Sympo- sium Integration in Dendrites and other Membranes , will be held from 1:00 PM to 5:30 PM on Saturday March 2, 2019, in the Baltimore Convention Center. The symposium will be followed by the Kenneth S. Cole Award ceremony and dinner, 6:30 PM–9:30 PM, at Westminster Hall, 519 W Fayette St, Baltimore. As always, any member of the Society is welcome to join us. But if you attend the symposium, why not consider joining the subgroup? The membership fees are essential to allow us to keep programming exciting symposia. They cover the costs of audio/visual equipment, the venue itself, and our coffee

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T H E N E W S L E T T E R O F T H E B I O P H Y S I C A L S O C I E T Y