Biophysical Society Bulletin | December 2022

Upcoming 2023 BPSMeetings

Towards aMore Perfect Union: MultiscaleModels of Muscle and Their Experimental Validation Canterbury, England, July 17–20, 2023 Abstract Deadline: March 20, 2023 | Early Registration Deadline: April 10, 2023 THEMATIC MEETING

Short talks will be selected fromamong submitted abstracts.

An emerging generation of computational models and modeling approaches that cross multiple temporal and spatial scales is enabling new understanding of the mechanisms that regulate striated muscle contraction. These models and their technical underpinnings rely on new, higher-order information about protein and sarcomere structural dynamics, and this is supported by the current resolution-revolution in structural biology. Coupling experimental and computational approaches provides a powerful approach to describe the functional properties and interactions of sarcomere proteins both at rest and during con traction. This understanding then offers new insights into mechanisms that regulate cardiac and skeletal muscle contractile function and its dysfunction in diseases. Moreover, such approaches support the identification of small molecule targets for therapeutic interventions and can predict their mechanism of action. The thematic meeting will provide a forum for colleagues from academia and industry to connect between disciplines and discuss their own advances and prospects for applying new computational and experimental tools. The aim is for a new generation of muscle researchers to forge close collaboration amongst themselves and bridge the gap between modelers and experimentalists.

ORGANIZING COMMITTEE Silvia Blemker , University of Virginia, USA Mike Geeves , University of Kent, United Kingdom William Lehman , Boston University, USA Andrew McCulloch , University of California, San Diego, USA

Michael Regnier , University of Washington, USA Jill Tardiff , University of Arizona, USA Jolanda van der Veldon , Amsterdam University Medical Center, The Netherlands

BPS CONFERENCE

Proton Reactions: From a Basic Science to Biomedical Applications Tahoe, California, USA, August 20–24, 2023 Abstract Deadline: May 8, 2023 | Early Registration Deadline: May 31, 2023

Short talks will be selected fromamong submitted abstracts.

We are pleased to announce that the Biophysical Society Conference on Proton Reactions: From Basic Science to Biomedical Applications originally planned for 2021 is now taking place in August 2023. A vast number of biologically important enzymes, transporters, and other molecules require the participation or transport of protons. Because the proton is unique in many re spects, its properties and reactions are often quite distinct from those of other ions. The invited speakers include chemists, structural biologists, and physiologists whose expertise encompasses a wide range of topics that are all related to the proton. We hope to encourage new understandings on levels from basic science to biomedical applications.

ORGANIZING COMMITTEE Ana-Nicoleta Bondar , University of Bucharest, Romania Thomas DeCoursey , Rush University Medical Center, USA

ADVISORY COMMITTEE Bertrand Garcia-Moreno , Johns Hopkins University, USA Marilyn Gunner , City College of New York, USA

Jessica Swanson , University of Utah, USA Greg Voth , University of Chicago, USA

For more information, visit www.biophysics.org/meetings

December 2022

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