Biophysical Society Bulletin | February 2018

February 2018

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2018 New&Notable SymposiumSpeakers Announced Six speakers have been selected for the 2018 New&Notable Symposium

Beat Fierz

Seok-Yong Lee

Patricia Clark

Eric Deeds

Katalin Torok

Susan Tsutakawa

Inside New & Notable Symposium

The Annual Meeting Program Chairs were challenged in making the selections this year due to the many outstanding nominations submitted by Society members. The speakers will present their work in San Francisco, during the Symposium on Wednesday, February 21, 1:00 pm –3:00 pm . The New & Notable Symposium will feature exciting new discoveries across a wide range of biophysical research, includ- ing biosensor development, single molecule fluorescence and cryo-EM analyses of biomolecular structure and dynamics, and systems biophysics. Anne Kenworthy and Francesca Marassi , Program Co-Chairs of the 62 nd Annual Meeting Program Committee, will co-chair the Symposium.

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Biophysicist in Profile

Public Affairs

Thematic Meeting

Publications

Annual Meeting

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Molly Cule

Going to the Annual Meeting? Pick up your button at the Society Booth.

Grants and Opportunities

Society Awards Member Corner Student Spotlight Important Dates Networking Events Biophysics Week Upcoming Events

Follow Annual Meeting events on Facebook, Twitter, and the Biophysical Society Blog throughout the Annual Meeting with scientific session news, press releases, and attendee blog posts. Follow along using the hashtag #BPS18.

Profile in Biophysics

Patrick McCarter Area of Research Quantitative Systems Pharmacology

Institution University of North Carolina, Chapel Hill

At-a-Glance

Patrick McCarter is a postdoctoral fellow in the Eshelman School of Pharmacy at the University of North Carolina, Chapel Hill, working in quantitative systems pharmacology, which seeks to under- stand the impact of drugs at all levels of physiology. His career thus far has been marked by his dedication to research focused on improving human health, and his openness to honest self-as- sessment and improvement.

Patrick McCarter

“My first real experience in science came after my freshman year in college,” shares Patrick McCarter , postdoctoral fellow in the Eshelman School of Pharmacy at University of North Carolina, Chapel Hill (UNC). “I worked as a summer student researcher in nuclear and particle physics at The Thomas Jefferson National Accelerator Facility. I enjoyed the collegial environment of the national lab and watching the different units working together to tackle a huge project.” He went on to receive his bachelor of science degree in physics at North Carolina Agricultural and Technical State University, and then continued there as he earned a master’s of science in compu- tational science and engineering. This was a challenging journey, but he approached it with rig- or. “I had no real idea of what biophysics was when I started college, but the idea of combining biology and physics to solve challenging problems in human health was really appealing to me, so I set out on a journey to become a biophysicist. My challenge was that because my physics department did not have a biophysicist, there was no roadmap for me to follow,” he says. To achieve his goal, McCarter pictured who he thought an “ideal” biophysicist would be, and then cre- ated a plan to become as much like them as possible. “This required an uncomfortable amount of introspection, where I determined that I just was not good enough at math to reach my goal. So I decided to first intently focus on learning math through physics, which came more naturally to me, and then once comfortable, apply that knowledge to biological prob- lems,” he shares. “It was difficult to stick with physics while struggling with math at first, but I was encouraged by my family and physics department, and also inspired by Richard Feynman’s idea, which paraphrased says that, ‘My attitude towards mathematics could be slightly disrespectful, in that I only needed to borrow enough math to do the physics…’ After a couple years of undergraduate physics, I became much bet- ter at math. By the time I finished the first year of my mas- ters, I was confident that I could use my physics background to investigate the biological problems that interested me.”

McCarter at a BPS Summer Program reunion with his cohorts.

As he was completing his master’s degree, he was still not quite sure that he wanted to commit to a PhD program. “I asked my thesis advisor if I could take time ‘mostly-off’ from my thesis research to attend the Biophysical Society’s 2010 Summer Program in Biophysics,” he says. “It turned out to be a really great decision for me. I trained in the lab of Dr. Max Berkowitz using computational biophysics to investigate peptide induced membrane permeabilization. The experience solidified my desire to pursue a PhD in biophysics, and be- cause I was working directly with PhD students and postdocs, I returned to my master’s program a better scientist.” Additionally, the connections he made during the summer program have been crucial in the years following his partic- ipation. “My summer course cohort is always available for support,” he says, “and over the years I’ve developed a strong relationship with the greater Biophysical Society. I feel like I belong here.”

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Profile in Biophysics

Officers President Lukas Tamm President-Elect Angela Gronenborn Past-President Suzanne Scarlata Secretary Frances Separovic Treasurer Kalina Hristova Council

McCarter earned his PhD from UNC in bioin- formatics and computational biology with a certificate in molecular and cellular biophysics and immediately began his current position and a postdoc in the Eshelman School of Pharmacy at UNC-Chapel Hill. “The goals of my current research are to identify mechanisms of resistance to anti-cancer therapies, and to develop strategies to overcome these mecha- nisms,” he shares. “To accomplish these goals, I am using quantitative systems pharmacology to investigate intracellular, intercellular, and in vivo mechanisms of therapy resistance.” “Our lab specializes in using mathematical models to understand targeted therapies, such as Epidermal Growth Factor Receptor inhibitors (anti-EGFR), and the impact of these targeted therapies on the body— a field called pharmacodynamics (PD). Our research is typically even more specialized in that we use a physiology-based pharmacokinetics/phar- macodynamics (PBPK/PD) modeling approach to explicitly consider the impact of physiology on the efficacy of the targeted therapies,” McCarter explains. “My interest in this type of research stems from a desire to make therapy more efficacious. Some patients respond well to anti-EGFR therapies, however the major- ity of patients either do not respond at all or quickly acquire resistance to the therapies. My research couples PBPK/PD models of anti-EG- FR therapies with in vitro and in vivo exper- iments to identify intracellular mechanisms that lead to discrepancies in responses to these therapies. The ultimate goal is to develop strategies that enhance therapeutic efficacy for as many patients as possible.” Communicating with people outside of the scientific community about his research is the most challenging and rewarding aspect of McCarter’s work as a biophysicist. “I think we all have a responsibility to share what we have learned with everyone. How do we who study disease bring comfort to those who are suffering from the disease?” he asks. “To me it is without a doubt the most challenging part of cancer research. No matter where you are or with whom you are speaking, there is almost always a person currently being impacted by a cancer with a personal follow-up story. And given that you may be the only scientist who

they know or have a some- what personal relationship with outside of the clinic, what you say will often either encourage or devastate them.” He plans to continue down his current path of health-re- lated research

Zev Bryant Jane Clarke Bertrand Garcia-Moreno Teresa Giraldez Ruben Gonzalez, Jr. Ruth Heidelberger Robert Nakamoto Arthur Palmer Gabriela Popescu Marina Ramirez-Alvarado Erin Sheets Joanna Swain Biophysical Journal Jane Dyson Editor-in-Chief Society Office Ro Kampman Executive Officer Newsletter Executive Editor Rosalba Kampman Managing Editor Beth Staehle Contributing Writers and Proofreaders Dorothy Chaconas Laura Phelan

McCarter with his wife Jocelyn at a wedding.

as he moves forward in his career. “I think at this point I have a responsibility to keep going as far as I can. My family through their relent- less encouragement, and the country through the external fellowships I received as a PhD student, have invested a lot in my training. My goal is to do everything possible to give them a generous return on their investments,” he says. “For biophysics, I hope that people will look at my experience and give more people a chance to be successful. I don’t have a scien- tific pedigree, but I do have a desire to help people through science. I think that that should be enough to be given a fighting chance.” “ When you’ve reached your goal, extend a hand to help someone reaching out to you. ” McCarter and his wife recently welcomed their first child, so he is quite busy these days between work and family. “I spend as much time around my family as possible…I will be trying to enjoy every minute of being a parent for next lifetime,” he says. As he continues to move forward in his career, he encourages those young biophysicists coming up behind him, “Be committed toward pursuing your goals. When it gets hard, don’t quit: just keep going. Find the people who will help you, and hold on to them. And when you’ve reached your goal, extend a hand to help someone reaching out to you.”

Caitlin Simpson Elizabeth Vuong Ellen Weiss Production

Ray Wolfe Catie Curry

The Biophysical Society Newsletter (ISSN 0006-3495) is published eleven times per year, January-December, by the Biophysical Society, 5515 Security Lane, Suite 1110, Rockville, Maryland 20852. Distributed to USA members and other countries at no cost. Canadian GST No. 898477062. Postmaster: Send address changes to Biophysical Society, 5515 Security Lane, Suite 1110, Rockville, MD 20852. Copyright © 2018 by the Biophysical Society. Printed in the United States of America. All rights reserved.

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Public Affairs

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Graduate Students Spared in the Final Tax Bill After a fierce lobbying effort by graduate students and others in higher education across the country and a considerable amount of press, Congress dropped the provision in the House tax bill that would have made the value of the tuition waivers taxable income. Graduate students will continue to be taxed on the salaries they receive for lab or teaching work, but not on the tuition discounts they receive. Thank you to the 270 members who sent over 950 messages to their elected officials letting them know how this provision would harm them and graduate education.

First Chief Facilities Officer BeginsWork at NSF

an additional 200 promising investigators. Promising inves- tigators were defined as those with no more than 10 years of NIH funding support. The targeted individuals would have scores in the top 25 percent of grant proposals. It turns out that implementation was difficult, the messaging was off, and NIH received push back on setting a 10-year deadline. At the December 15 meeting of the Advisory Council to the Director, NIH Deputy Director Larry Tabak announced that the plan will be tweaked to target younger and at-risk in- vestigators, defined as those who are at risk of losing all their funding. Tabak said NIH still hopes to award an additional 400 grants per year to this targeted group. He also clarified that not all investigators in these targeted groups who score in the top 25 percent of proposals will be funded by NGRI—it is just a benchmark indicating that these grants scored well and are worthy of funding. NIH had received calls from many inves- tigators in the targeted groups who scored within the top 25 percent and did not get funded; they felt misled. An NGRI working group is expected to release a report in June 2018, at which time, there will probably be additional tweaks to the program.

With the start of 2018, the National Science Foundation (NSF) added a new member to its management team. Jim Ulvestad is the agency’s first chief officer for research facilities. Congress directed NSF to create this position to improve oversight of NSF’s large facilities throughout their lifecycles. He will also work with the newly created Facilities Governance Board to develop standards

Jim Ulvestad

for facilities operations, and oversee the Foundation’s mid- scale research infrastructure program. Prior to assuming this role, Ulvestad was the acting head of NSF’s Mathematical and Physical Sciences Directorate. NIH Revises the Next Generation Researchers Initiative Just six months after scrapping a plan to limit funding per investigator to free up money for young investigators and replacing it with the Next Generation Researchers Initiative (NGRI), the National Institutes of Health (NIH) has announced changes to that program. Through NGRI, NIH had planned to annually fund an additional 200 early career investigators and

President Trump provided some insight into his vision for the 2019 federal budget in the State of the Union on January 30. His full budget proposal is due to Congress on February 5.

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Biophysical Society Thematic Meeting

Genomic tools are becoming essential in molecular and personalized medi- cine by virtue of their capacity to analyze diversity within the human genome. Whereas genomic variability at the sequence level is manifestly involved in health and diseases of organisms, little is known about the roles that such vari- ability plays in the physical organization of genomes. The theme of this meet- ing is an exploration of the long-overdue application of biophysical methods in genomics, emphasizing structural and functional aspects of genome and transcriptome dynamics. Proposed topic areas include extremophile genomes, highly compact genomes, extrachromosomal circular DNAs, circular and micro RNAs, DNA viruses and viroids, and other nucleic-acid and chromatin structures having potential roles in genome regulation. Genome Biophysics: Integrating Genomics and Biophysics to Understand Structural and Functional Aspects of Genomes August 19–24, 2018 | Santa Cruz, California

ORGANIZING COMMITTEE Sarah Harris , University of Leeds, United Kingdom Stephen Levene , University of Texas at Dallas, USA

Julia Salzman , Stanford University, USA Massa Shoura , Stanford University, USA

SPEAKERS Nadav Ahituv , University of California, San Francisco, USA Javier Arsuaga , University of California, Davis, USA Ami Bhatt , Stanford University, USA Xiavier Darzacq , University of California, Berkeley, USA Martin Depken , Delft University of Technology, The Netherlands

Charles Dorman , Trinity College, Ireland Andrew Fire , Stanford University, USA

Laura Iandweber , Columbia University, USA Joanna Kelly , Washington State University, USA Alan Lambowitz , University of Texas at Austin, USA Christian Micheletti , SISSATrieste, Italy Sergei Mirkin , Tufts University, USA Shinichi Morishita , University of Tokyo, Japan Mario Nicodemi , University of Naples, Italy Wilma Olson , Rutgers University, USA Karsten Rippe , Heidelberg University, Germany Marc Salit , NIST, USA

Tamar Schlick , NewYork University, USA David Schwartz , University of Wisconsin, USA Andrzej Stasiak , University of Lausanne, Switzerland Tim J. Stevens , MRC Laboratory of Molecular Biology, United Kingdom Bo Wang , Stanford University, USA Sarah Woodson , John Hopkins University, USA Zeba Wunderlich , University of California, Irvine, USA Alexandra Zidovska , NewYork University, USA

Abstract Submission & Registration Deadline: April 2, 2018

For more information, visit www.biophysics.org/2018SantaCruz

Publications

Know the Editor Amedeo Caflisch

BJ Sponsors Awards at Recent IDP Conference The Biophysical Journal was pleased to support young inves- tigators by sponsoring poster awards at the recent Interna- tional Conference on Intrinsically Disordered Proteins: Forms, Functions, and Diseases in Mohali, India. Four winners, including three students and one postdoc, were selected from more than 100 posters. Students Reema Kathuria, Department of Biological Sciences Centre for Protein Science, Design and Engineering Indian Institute Of Science Education and Research (IISER) Mohali Aishwarya Agarwal, Amyloid Biology Laboratory Indian Institute of Science and Educational Research (IISER), Mohali Sasirekha Narayanasamy, Department of Biotechnology Bhupat and Jyoti Mehta school of Biosciences, Indian Institute of Technology Madras (IITM) Postdoc Bankinidhi Sahoo, Department of Chemical Sciences Tata Institute of Fundamental Research

Department of Biochemistry Univeristy of Zurich Editor, Proteins

Amedeo Caflisch

Who would you like to sit next to at a dinner party? The late Mario del Monaco (1915–1982) and Luciano Pavarotti (1935–2007). In my opinion, they have been the best dra- matic tenor and lyric tenor, respectively, of the past century. Del Monaco excelled, both as a singer and actor in Verdi’s Otello, which is arguably the most difficult tenor part of all of Verdi’s production. Luciano Pavarotti’s voice was the per- fection, and in several operas of Italianrepertoire, including the most difficult tenor roles in the operas of Rossini, Bellini, Verdi, and Puccini. Both del Monaco and Pavarotti had a great talent and the so-called “squillo” in the voice, which is a very rare gift. Importantly, they were practicing and/or rehearsing every day. Professional singing, particularly operatic singing, is similar to research science as you need both talent and hard work. At the dinner, I would not ask them to sing but rather which vocal exercises they practiced. (Singing, mainly in choirs, is my major hobby). How do you stay on top of all the latest developments in your field? This is difficult because of the explosion of journals and papers. The problem is exacerbated because the research activities in my group are rather broad as we not only develop simulation protocols and analysis tools for complex systems (mainly atomistic simulations of proteins) but also perform biochemical and biophysical assays to validate the predictions of our high-throughput docking campaigns. My PhD stu- dents and postdocs keep me updated. They are very efficient in identifying relevant papers with novel methods and/or results. Furthermore, I receive periodically table of contents by e-mail from a few journals that I want to scan myself. In addition, I read many manuscripts as reviewer for several journals and as member of the editorial board of the Biophysical Journal.

Meet the Editor-in-Chief at the BPS Annual Meeting

Meet Jane Dyson , Editor-in-Chief of Biophysical Journal at Booth 200 in the Exhibit Hall, Monday, February 19. Stop by between 2:00 and 3:00 pm to discuss publication of your work or to let her know your thoughts about Biophysical Journal .

Numbers By the

In 2017, 12% of articles published in Biophysical Journal were open access.

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Horiba Scientific @HScientific

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Annual Meeting

What You Should KnowBefore Heading to the Annual Meeting Registration

Thank you to our sponsors: AAT Bioquest Allen Institute for Cell Science Alvéole APL Bioengineering Asylum Research, an Oxford Instruments Company Beckman Coulter Life Sciences Biochemistry BioLogic USA Bruker Corporation Burroughs Wellcome Fund Carl Zeiss Microscopy Cellular Dynamics International, a FUJIFILM company Chroma Technology Corporation Dynamic Biosensors GmbH FUJIFILM Dimatix Inc Hamamatsu Corporation HEKA Elektronik HORIBA Scientific Journal of General Physiology KinTek Corporation LUMICKS BV Mad City Labs Malvern Panalytical MDPI Molecular Devices LLC Nanion Technologies GmbH Pall Fortebio Photonics Media Physics Today Princeton University Press Science|AAAS Sophion Bioscience A/S Sutter Instrument TA Instruments The Journal of Physical Chemistry Wyatt Technology

Poster Printing Service/Poster Pick-Up Presenting a scientific poster and want to avoid the hassle of transporting it to the meeting? Have it printed and ready for pick-up at Tray Printing in the Moscone Center South Lobby. Options include a smooth matte vinyl or poly- ester fabric. Place your order before 12:00 PM Central Time (USA) on Wednesday, February 14, to receive discounted rates. After February 14, rush orders for posters must be submitted at least 48 hours prior to your presentation. RUSH posters submitted will be produced on a first-come, first-serve basis. Tray Inc. will notify you ASAP via email if they cannot produce your poster on time. Typically, orders submitted on the Friday before the Annual Meeting will not be ready until Monday afternoon. Free Networking Cards for Poster and PlatformPresenters Sponsored by Quartzy, the world’s leading free online lab management platform. Are you presenting in a platform or poster ses- sion at BPS this year? If so, you already have 25 pre-printed Networking Cards waiting for you. Networking cards are like business cards, but de- signed just for scientists. They carry your contact information, the title of your presentation, your presentation date and time, and your abstract. Pick up your networking cards at the Quartzy counter near registration in the Moscone Center South Lobby.

Look for your registration confirmation with a QR code that will be sent by email, Monday, February 12. Print this confirmation and bring it with you to speed up the process of picking up your badge and meeting materials. Registration, badge pick-up, scientific sessions, and posters are all located in the Moscone Convention Center South Lobby. Onsite Registration Hours: Friday, February 16 3:00 pm –5:00 pm Saturday, February 17 8:00 am –6:30 pm Sunday, February 18 – Tuesday, February 21 7:30 am –5:00 pm Housing Confirmation If you booked your hotel reservation through the official BPS housing bureau, CHP Housing, you should have received your confirmation via email. If you have not, contact the housing bureau directly toll free at 1-800-274-9481. Outside the United States, please call 1-415- 813-6088 and select option 4. Art of Science Image Contest The 12 finalist images will be on display in the Exhibit Hall. Don’t forget to stop by and vote for your two favorite images. Voting will be open until 12:00 pm on Tuesday, February 20. Ballots will be distributed with your badge at the onsite registration desks.

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Annual Meeting

Fueling Discovery through Biophysics

Green Cards for Scientific Researchers: How toWin Your EB-1A/NIWCase, with Getson & Schatz Brian Getson is a leading US immigration lawyer who rep- resents scientific researchers applying for green cards in the EB-1A, EB-1B, and NIW categories. Learn about the US im- migration process and how to maximize your chances of im- migration success during his workshop on Sunday, February 18, 10:30 am –11:30 am . He will answer questions and provide free legal consultations after the presentation and throughout the Annual Meeting in the Career Development Center.

Stop by the Society Booth located in the Moscone South Lobby to purchase an Annual Meeting T-Shirt as well as other Society merchandise.

Undergraduate Student Lounge Need a quick place to relax or catch up on coursework while at the Annual Meeting? Visit the Undergraduate Student Lounge on the second level of Moscone South. Special Events Opening Mixer Saturday, February 17, 5:00 pm – North Lower Lobby Presentation of Awards and Biophysical Society Lecture, delivered by Jennifer Doudna Monday, February 19, 8:00 pm – North Lower Lobby, Room 24/25 Reception/Dance Monday, February 19, 9:30 pm – Marriott Marquis, Yerba Buena Ballroom

Plan. Sync. Connect.

• Create your itinerary • View Abstracts • Search by Keyword • Search by Technique

• Search Authors • Browse Exhibitors • Be Social • Map your Experience

Visit www.biophysics.org/2018meeting for more information on the Biophysical Society Events Desktop Planner and Events App. Search keyword "BPS Events" on the app stores below.

The enormous advantage of being a part of the Biophysical Society is the broad scientific community provided by the Society. In my particular field of interest, I am not aware of any other organization with a similar number of ion channel researchers that are brought together during the Annual Meeting. —Dierk Thomas, Universität Heidelberg

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Career Developement

How to Ask Questions at a Conference

New at the 2018 Annual Meeting! Data Visualization Monday, February 19, 2:15 pm –3:45 pm

Working up the nerve to ask questions at conferences can be hard, but you should definitely pat yourself on the back for taking the initiative to try. That being said, there are some things that you can think about to help you ask your question most effectively and to make the best impression.

This interactive session will focus on how to best represent your data visually, whether for a talk, a poster, or publish- ing a paper. New tools and approaches are now enhancing how we interact with our data. How to determine the best approach, summarize complex material in easily digest- ible forms, and why simpler is better will all be discussed. Datasets and real examples of visual interpretations by participants will be discussed. Please visit https:/www.dropbox.com/request/ hAk6Aa0bOeUrHV1A2x2H to drop your sample files.

Statements We’ve all seen it happen. The statement “question” is all too familiar at academic conferences. You may have seen audi- ence members make their own statement about the topic at hand. More often than not, people “asking” these kinds of questions are not really trying to get information. Rather, they are usually trying to prove they are right or why they do not agree with the speaker; possibly trying to one-up the speaker. Don’t do this. It’s hard enough to think on your feet, but it’s even more difficult to have to shift to someone else’s point of view. Ask a question publicly or privately It may be scary standing up at a conference and asking a question. Before getting up the nerve to approach people at random or asking a question during a session at a large con- ference, try practicing at smaller events, such as those around your university or company. Starting small will help you build up the confidence to start raising your hand! Another tech- nique you could try is to approach a speaker right after his/ her session. This alleviates some of the nerves you may feel about asking a question in a large room full of people, and can lead to a longer discussion and further engagement. Repeating a question If you do have a question you want to ask, make sure that it wasn’t already asked and answered earlier during the Q&A or during the presentation. This can be hard, especially if you had to duck out of the session at some point. If you are not sure whether your question has been addressed, you can mention this and/or make it clear you are asking for clarification in order to not irritate the speaker and the audience. Be sure to make the most of the BPS Annual Meeting —be confident and ask your question!

Special issue Reconstituting cell biology Guest edited by Manuel Théry (HôpitalStLouis,ParisandCEA,Grenoble) Submission deadline: 15th February 2018 Call for papers Journal of Cell Science is pleased to welcome submissions for this upcoming special issue. We encourage submissions of Research Articles, Short Reports and Tools & Resources papers. This special issue is intended to have a broad scope, so we are open to articles froma wide spectrumof areas. All special issue papers will be published shortly after acceptance, and collected together in a special issue scheduled for release in early 2019.

Find out more at: http://jcs.biologists.org/content/call-papers-reconstituting-cell-biology

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Allen Cell Explorer How can our data, tools and cells help you?

The Allen Cell Explorer is the data portal for the Allen Institute for Cell Science, where you can explore our publicly available quality-controlled data, tools and models. The portal provides information about our gene edited cell lines, detailed methods and a unique view into the organizational diversity of human iPS cells by combining large-scale 3D image data, predictive models and cell observations. • Visit us at booth #311 to try our Virtual Reality experience and see demonstrations of 3D CellProfiler • Attend our Platform Session, “Studying Stem Cell Organization Using “Label- Free” Methods and a Novel Generative Adversarial Model” • Attend our presentations and visit our posters For more information, visit alleninstitute.org/biophys18

alleninstitute.org | allencell.org

Grants & Opportunities

Consequences of Amyloid Protein Polymorphisms in Alzheimer’s Disease Applications are invited for innovative research fo- cused on understanding the consequences of amyloid protein polymorphism in regulation and initiation of early pathogenesis in Alzheimer’s disease. Specifically encouraged are collaborative approaches designed to identify and characterize the regulation of biochemical and cellular pathways involved in subtypes of Alzhei- mer’s disease. Deadline: March 28, 2018 Website: https:/grants.nih.gov/grants/guide/rfa-files/ RFA-AG-18-025.html

Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research Applications are invited to enhance the pool of highly trained investigators from diverse backgrounds under- represented in research. Individuals are targeted with research interests grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, and hematologic Who may apply: Institutions with eligible faculty mem- bers to undertake special study and supervised research under a mentor who is an accomplished investigator in the proposed research area and who has experience in developing independent investigators. Website: https:/grants.nih.gov/grants/guide/rfa-files/ RFA-HL-18-026.html diseases and sleep disorders. Deadline: February 20, 2018

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Communities

Nominations NowBeing Accepted for 2019 Society Awards

The Biophysical Society is accepting nominations for its 2019 awards now through May 1, 2018. There are three newly established awards: The BPS Innovation Award, The BPS Award in the Biophysics of Health and Disease, and The Ignacio “Nacho” Tinoco Award of the Biophysical Society. The BPS Innovation Award will be presented to a BPS member who advances our fundamental understanding of biological systems through the development of novel theory, models, concepts, techniques, or applications. The BPS Award in the Biophysics of Health and Disease will honor a BPS member who has made a significant contribution to understanding the fundamental cause or pathogenesis of disease, or to enabling the treatment or prevention of a disease. The Ignacio “Nacho” Tinoco Award of the Biophysical Society recognizes the scientific contributions, work, and life of an outstanding biophysical chemist, educator, and mentor. It is intended to acknowledge meritorious investigators who make fundamental and/or seminal contributions to the physical chemistry of biopolymers and/or who actively promote and sustain a collaborative, inclusive, and engaging research environment in the field.

Other Awards: • Anatrace Membrane Protein Award • Avanti Award in Lipids • Michael and Kate Bárány Award • Margaret Oakley Dayhoff Award

• Fellow of the Biophysical Society Award • Founders Award • Emily M. Gray Award • Kazuhiko Kinosita Award in Single Molecule Biophysics

Awards will be presented at the 2019 Biophysical Society Annual Meeting in Baltimore, Maryland. For information and to submit a nomination, visit www.biophysics.org/awards.

Networking and Personal Branding: Two Keys to Success March 13, 2018, 2:00 pm EST Presenter: DavidWarshaw

So you publish in high impact journal and your science is exceptional, but do people really know who you are? Amplify your scientific persona through networking and personal branding. Simple tips are provided to help set you apart in the public and communication domains, which can impact your future and continued success. The webinar is designed for early career scientists but it’s never too late.

David Warshaw

Register Today at biophysics.org/webinars

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Member Corner

Members in the News

Jin O-Uchi , Rhode Island Hospital, Brown University, and Society member since 2006, was awarded the 2017 Shih-Chun Wang Young Investigator Award from the American Physiological Society.

Have you or someone you know recently received an award or been acknowledged for an achievement in the area of biophysics? Email society@biophysics.org to let BPS know.

Jin O-Uchi

Student Spotlight

Xavier Bonner Morehouse College

growth. In the future I hope to contribute to the great work that is currently being done in the field of biophysics with an emphasis on mechanisms of macromolecular machines. One reason why this field attracts me is because it is fascinating that the biological matter we contain works in a program- mable fashion.

I am majoring in Physics and Computer Science. Science has challenged me in many ways that have contributed to my success and personal

Xavier Bonner

Your BPSMembership Your membership includes many benefits that will help you throughout your career and lifelong learning journey. Your member benefits allows you to: • Get published for less - publish in the Biophysical Journal and pay reduced rates for pages and print color and receive free online color • Advance your career – through free webinars, career development resources, BPS Job Board and more • Save money on meetings – get significant member discounts to the BPS Meetings • Expand your network and stay connected to your peers through BPS meetings and events Visit www.biophysics.org to access your member benefits today.

Important Dates

62 nd BPS Annual Meeting February 17–21, 2018

Biophysics Week March 12–16, 2018

BPS Thematic Meetings April 2, 2018 Abstract Submission and Registration: Genome Biophysics May 7, 2018 Abstract Submission: The Heart by Numbers June 4, 2018 Early Registration: The Heart by Numbers

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Communities

Upcoming 2018 Networking Events

Since 2011, Society members have hosted networking events to bring together local scientists to discuss various topics in biophysics and to have a chance to get together. These events promote interactions between members and non-members interested in biophysics and the Society. Congratulations to the selected networking events from the most recent call for sub- missions. New and renewing networking event mini-grant recipients are: Jeopardy & Pizza

7th Bluegrass Molecular Biophysics Symposium May 14, 2018 Lexington, KY Ontario Networking Event in Biophysics (“ONE”-Biophysics)

Date TBD Urbana, IL Green Mountain Molecular Biophysics Symposium

March 9, 2018 Burlington, VT

June 2018 (Exact Date TBD) Mississauga, Ontario, Canada For more information on networking events, please visit www.biophysics.org/networkingevents. From the Blog New Year’s Resolutions for Researchers http:/ biophysicalsociety.wordpress.com

The Ribosome Running at (Half-)Full Tilt Authors Ryan Jamiolkowski, Chunlai Chen, Barry Cooper- man, and Yale Goldman shared the story behind their steampunk-style Biophysical Journal cover: https:/ bio- physicalsociety.wordpress.com/2017/12/05/the-ribo- some-running-at-half-full-tilt/

As one year comes to a close and the next begins, con- versation often turns to New Year’s resolutions. At the start of 2018, we spoke with three incoming Biophysical Society Council members about their goals for 2018: https:/ biophysicalsociety.wordpress.com/2017/12/29/ new-years-resolutions-for-researchers/

February 2018

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T H E N E W S L E T T E R O F T H E B I O P H Y S I C A L S O C I E T Y

Biophysics Week is a global effort aimed at encouraging connections within the biophysics community and raising awareness of the field and its impact among the general public, policy makers, students, and scientists in related fields. March 12–16, 2018

BiophysicsWeek Partners

Monday, March 12 • Biophysics at NIH—Lab Tour for Congressional Staff • Communicating Science 3Ways, Part 1 Tuesday, March 13 • Networking and Personal Branding: Two Keys to Success Webinar (DavidWarshaw)

Wednesday, March 14 • Communicating Science 3Ways, Part 2

Thursday, March 15 • The Science of Unconscious Bias Video Seminar • Liquid-liquid Phase SeparationWebinar (Tanja Mittag) Friday, March 16 • Communicating Science 3Ways, Part 3, and an Online Chat • Capitol Hill Briefing featuring Jennifer Lippincott-Schwartz

Order Your T-Shirt Today

Order online at biophysics.org/BiophysicsWeek or purchase at the Biophysical Society Booth at the BPS Annual Meeting.

On the website you will find information about additional Biophysics Week events taking place around the world to celebrate the week as well as resources you can use, such as lesson plans, trivia quizzes, “what is biophysics” video clips, and profiles. Materials will be added throughout the week!

Visit biophysics.org/ BiophysicsWeek for more information.

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Biophysical Society

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February 2018

T H E N E W S L E T T E R O F T H E B I O P H Y S I C A L S O C I E T Y

Upcoming Events

March March 1-2 BIOTEC Forum 2018 – Biophys- https:/webapp.biotec.tu-dres- den.de/conferences/event/32/ March 21-24 3rd International Symposium on Cryo-3D Image Analysis Lake Tahoe, CA http:/ cryoem.bcm.edu/cryo- em/events/view_workshop/1 ics in the Nucleus Dresden, Germany

April April 2-6 Drug Discovery Chemistry San Diego, CA http:/www.drugdiscovery- chemistry.com/ April 12-14 Second MCW Redox Biology Symposium Milwaukee, WI https:/www.mcw.edu/ Redox-Biology-Pro- gram/2018-Symposium.htm

May May 14-17 Cellular Mechanisms Driven by Liquid Phase Separation Heidelberg, Germany https:/www.embo-em- bl-symposia.org/sympo- sia/2018/EES18-03/index. html May 16-18 NIMBioS Tutorial – Applica- tions of Spatial Data: Ecologi- cal Niche Modeling Knoxville, TN http:/www.nimbios.org/tu- torials/TT_SpatialData

June June 13-15 5th NovAliX Conference “Bio- physics in Drug Discovery” Boston, MA https:/www.ldorgani- sation.com/v2/produits. php?langue=english&cle_ menus=1238916576 June 20-22 6th International Iberian Bio- physics Congress Castellon, Spain http:/www.sbe2018.com/

Please visit www.biophysics.org for a complete list of upcoming events.