Biophysical Society Bulletin | June 2023

Publications

Know the Editor Guy Genin

Washington University in St. Louis Editor, Cell Biophysics Biophysical Journal

Guy Genin

What are you currently working on that excites you? What an exciting time this is for the whole field of mech anobiology! The basic principles of mechanotransduction, mechanoresponsiveness, and mechanical memory are coming together to the point where their clinical application is possible, with many groups and even start-ups now applying these basic principles to patient care. The field has long been able to perform stress analysis on tissues, but now many cell types can be included in these analyses, as well as the way they evolve themselves and their local microenviron ments. Fibroblasts respond very differently to different types of stress fields, and my collaborators and I are working to harness these responses for improved healing after rotator cuff repair and dermal grafting. Details are hopefully coming soon—keep your eyes on the pages of Biophysical Journal ! How do you stay on top of all the latest developments in your field? How times have changed! Does anyone else remember all the way back to the era of lounging with the paper edition of Biophysical Journal ? Now, by the time that the paper versions come out—and even the tweets for that matter—the news is old. For the latest breakthroughs, I look through preprint servers, join working group meetings of the National Science Foundation’s Science and Technology Center for Engineering Mechanobiology (all are invited!), and take notes at the Bio physical Society Annual Meeting. Through all these changes to publishing, I find the perspective pieces in Biophysical Jour nal to be increasingly valuable. All the new facts I need are on preprint servers, and all the new disinformation I need is on Twitter, but for new perspectives, I turn to “New and Nota ble” articles and Reviews in Biophysical Journal to learn about emerging ideas.

Editor’s Pick Biophysical Reports

Super-resolution reconstruction in ultrahigh-field MRI Macy Payne, Ivina Mali, Thomas Mueller, Mary Cain, Ronen Segev, Stefan H. Bossmann “Ultrahigh-resolution magnetic resonance imaging is critical for increasing the understanding of a variety of biological sys tems. It is a noninvasive strategy that can be repeated to fol low the progression of diseases, monitor growth over broad time frames, and extract a variety of quantitative parameters to monitor tissue structure, organization, and health. Unfor tunately, ultrahigh-resolution imaging comes with increased time costs and low signal/noise and contrast/noise ratios and is often limited by the overall instrument strength available. Super-resolution reconstruction is a rapidly growing area that allows for ultrahigh-resolution imaging at clinical strengths, increasing image clarity in the process. In this article, the authors assess the validity of the results gained from the application of super-resolution reconstruction and illustrate the benefits and limitations across various samples.”

Version of Record Published March 29, 2023 DOI: https:/doi.org/10.1016/j.bpr.2023.100107

June 2023

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