Biophysical Society Bulletin | March 2020

Thematic Meetings

Upcoming Thematic Meetings

Spatial Organization of Biological Functions

Bangalore, India August 16–19, 2020

Physical and Quantitative Approaches to Overcome Antibiotic Resistance Recent studies have shown that the dynamic spatial organization of different molecular components and activities within a cell and different cells within a tissue or community play critical roles in enabling the full functionality of the organism. As the significance of this field has been increasingly appreciated, it is now time to bring together leading scientists in the studies of the spatial organization of biological functions to discuss current advances, share expertise, and most importantly, define the underlying biophysical principles. This thematic meeting will focus on a diverse set of topics such as intracellular function- al compartmentalization, molecular organizations in the membrane and in the cytosol, three-dimensional architecture of physical compartments and cellular activities, pattern formation at different length and time scales, tissue structures, biofilms, and host-commen- sal organizations. Early Abstract Deadline: April 17, 2020 Early Registration Deadline: April 17, 2020 Antibiotic resistance is a pressing global challenge to human health, threatening to reverse many of the great health advances of the 20th century. In response to this challenge, the global scientific community has mobilized to address both the microbiological and the medicinal-chemistry aspects of antibiotic resistance. This meeting will bring together biophysical and bioengineering researchers working to diagnose, understand, and overcome antibiotic resistance. Key questions that will be addressed include: how do the limitations of (1) target recognition, (2) enzymatic degradation, and (3) small-molecule uptake shape the available space of antibiotics; how do bacteria communicate and interact as multicellu- lar communities; how does bacterial small-molecule transport function so differently than mammalian cell small-molecule transport; and how does the extracellular environment reinforce antibiotic resistance. Engineering approaches and the biophysical methodologies of spectroscopy, single-molecule and single-cell microscopy, computational modeling, and development of functional assays are uniquely suited to help answer these questions. Early Abstract Deadline: May 1, 2020 Early Registration Deadline: May 20, 2020 Stockholm, Sweden August 30–September 2, 2020

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