Biophysical Society Bulletin | May 2023

Publications

Know the Editor Ulrike Endesfelder

Editor’s Pick Biophysical Journal Mechanical memory stored through epigenetic remodeling reduces cell therapeutic potential Adrienne K. Scott, Eduard Casas, Stephanie E. Schneider, Alison R. Swearingen, Courtney L. Van Den Elzen, Benjamin Seelbinder, Jeanne E. Barthold, Jennifer F. Kugel, Josh Lewis Stern, Kyla J. Fos ter, Nancy C. Emery, Justin Brumbaugh, and Corey P. Neu “Tissue regeneration procedures, such as cartilage defect repair (e.g., matrix-induced autologous chondrocyte implanta tion), often require cell expansion processes to achieve suffi cient cells to transplant into an in vivo environment. However, the chondrocyte cell expansion on 2D stiff substrates induces epigenetic changes that persist even when the chondrocytes are transferred to a different (e.g., 3D) or in vivo environment. Treatments to alter epigenetic gene regulation may be a viable strategy to improve existing cartilage defect repair pro cedures and other tissue engineering procedures that involve cell expansion.” I don’t think there’s any hidden magic here: I have an alert for PubMed, I regularly attend various conferences, I like to invite guest speakers to our institute colloquium, I scroll (too often) through my Twitter feed, I read recent reviews or commentar ies on certain topics when I come across them (should do this more often!), and we have our group channel on new litera ture as well as our journal club every two weeks. titative and precise single-molecule methods have become, e.g., when we measure the kinetochore architecture in our current structural work. At the same time, we are still pushing the technical limits through new developments, and I get insanely excited when we see better results from a new type of sensor or establish single-molecule imaging for a new organism, such as when we recently added the archaeon Haloferax volcanii to the organisms that can be super- resolved. How do you stay on top of all the latest developments in your field?

Universität Bonn Associate Editor Biophysical Reports

Ulrike Endesfelder

What are you currently working on that excites you? Oh, many different elements; that is the beauty and the challenge of interdisciplinary research! In general, we follow the dynamics of single molecules in microbial organisms and try to understand their molecular life in their native environ ment as it is just happening. We are driven by our biological questions, and it is absolutely mind blowing to see how quan

Version of Record Published March 3, 2023 DOI: https:/doi.org/10.1016/j.bpj.2023.03.004

Call for BPS Student Chapters Interested in growing your educational and career opportunities? Biophysics students and their mentors can form their own Biophysical Society Student Chapter! Applications for new Student Chapters are being accepted until May 15 . For more information, a complete list of instructions, and a list of existing Chapters, visit www.biophysics.org/student-chapters.

May 2023

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