Biophysical Society Bulletin | November 2018

Annual Meeting

Annual Meeting

Subgroup Saturday Annual Meeting Symposia The Society’s 15 subgroups will hold symposia and business meetings on Saturday, March 2, 2019, in Baltimore, Maryland. For complete session information for each subgroup visit www.biophysics.org/2019meeting. Bioenergetics, Mitochondria, and Metabolism Subgroup Co-Chairs: Elizabeth Jones , Yale University, USA, and George Porter , University of Rochester, USA Speakers: William A. Cramer , Purdue University, USA Introduction: A New View of Organelle Energy Transduction: Super-Complexes Werner Kühlbrandt , Max Planck Institute for Biophysics, Germany Bioengineering Subgroup Chair: Amir Farnoud , Ohio University Speakers: Ka Yee Lee , University of Chicago, USA Susan Daniel , Cornell University, USA Golgi-on-a-Chip for the Cell-free Bio-nanomanufacturing of Pro- tein Therapeutics Jennifer Elisseeff , Johns Hopkins University, USA Immunoengineering in Regenerative Medicine Daniel Hammer , University of Pennsylvania, USA Upstream Migration of Amoeboid Cells: Dynamics and Memory Mark Uline , University of South Carolina, USA Utilizing the Synergistic Power of Molecular Theory and Molecular Simulation to Solve Bioengineering Problems Biological Fluorescence Subgroup Chair: Paul Wiseman , McGill University, Canada Speakers:

Lucy Shapiro , Stanford University, USA A Bacterial Membraneless Organelle Sequesters a Signaling Path- way that Drives Spatial Regulation of Cell Function Mark Leake , York University, United Kingdom Illuminating the Black Box of DNA-Protein Interactions Shana Elbaum-Garfinkle , City University of New York, USA Protein Phase Separation and Emergent Material Properties Kenwyn C. Huang , Stanford University, USA Conformational Dynamics of a Bacterial Actin Filament Predict in vivo Filament Length Danny Hatters , University of Melbourne, Australia Proteome Aggregation Patterns under Proteostasis Stress as Signatures for Understanding Huntington’s Disease Cell Biophysics Subgroup Chair: Jie Xiao , Johns Hopkins University School of Medicine, USA Speakers: Haw Yang, Princeton University, USA Unsupervised Statistical Learning of the Structural and Kinetic Elements in Multi-Resolution Dynamics Kandice Tanner , National Institutes of Health, USA High Frequency Active Microrheology Reveals Mismatch in 3D Tumor Intracellular and Extracellular Matrix Viscoelasticity Liedewij Laan , Delft University of Technology, The Netherlands Evolutionary Self-organization: Lessons from the Yeast Polariza- tion Machinery Christine Payne , Duke University, USA TiO2 Nanoparticle-cell Interactions: Importance of Protein Corona Johan Elf , Uppsala University, Sweden Genome-wide Single-cell Biophysics Jung-chi Liao , Academia Sinica IAMS, Taiwan Centriole Interaction Infrastructure Revealed by Superresolution Microscopy David Rueda , Imperial College School of Medicine, United Kingdom Imaging Cellular RNAs at Single Molecule Resolution with Fluor- genic RNA-Mango Aptamers Cryo-EM Subgroup Chair: Jenny Hinshaw , National Institutes of Health, USA Speakers: Alberto Bartesaghi , Duke University, USA Streamlining Workflows for Structure Determination by Single- Particle Cryo-ET Sub-Volume Averaging

Tim Grant , Howard Hughes Medical Institute, Janelia Campus, USA New Developments in the cisTEM Software Package Scott Stagg , Florida State University, USA Throughput and Resolution with a Next Generation Direct Detec- tor Alex Noble , New York Structural Biology Center, USA Cryo-tomography Methods and Spotition Thomas Marlovits , Center for Structural Systems Biology, Hamburg, Germany StarMap: Rosetta Refinement controlled from Chimera X Julia Mahamid , European Molecular Biology Laboratory, Germany Molecular Views into Cellular Function by In situ Cryo-Electron Tomography Exocytosis & Endocytosis Subgroup Chair: Amy Lee , University of Iowa, USA Speakers: Ira Milosevic , European Neuroscience Institute, University Medical Center Göttingen, Germany Regulation of Vesicle Acidification at the Neuronal Synapse Ed Chapman , University of Wisconsin, USA Contrasting the Functions of Synaptagmins 1 and 17 Nils Brose , Max Planck Institute of Experimental Medicine, Germany Synaptic Vesicle Priming and the Unique Features of Regulated Exocytosis at Nerve Cell Synapses Justin Taraska , National Institutes of Health, USA Imaging the Nanoscale Structure of Endocytosis and Exocytosis with Light and Electron Microscopy Intrinsically Disordered Proteins Subgroup Chair: Tanja Mittag , St. Jude Children’s Research Hospital, USA Jean Baum , Rutgers University, USA Modulating Alpha-synuclein Aggregation through IDP-IDP Interac- tions Jeetain Mittal , Lehigh University, USA Identifying Sequence-determinants of Protein Liquid-Liquid Phase Wolfgang Peti , University of Arizona, USA IDPs Enable Substrate Specificity of Protein Phosphatases Gary Pielak , University of North Carolina, Chapel Hill, USA Tardigrade Proteins and Desiccation Tolerance Joan-Emma Shea , University of California- Santa Barbara, USA Self-Assembly of the Tau Protein: Fibril Formation and Complex Coacervation

Cryo EM of Mitochondrial Super-Complexes William Dowhan , University of Texas Health Science Center, USA A Requirement for Cardiolipin in the Organization and Function of Mitochondrial Super-complexes Rosemary Stuart , Marquette University, USA Rcf1 and Rcf2: Central Role in Cytochrome c Oxidase Enzymology and Support of the Proton Motive Force Robert Gennis , University of Illinois, USA Structure of the Alternative Complex III from Flavobacterium John- soniae within a Supercomplex with Cytochrome aa3 Helmut Kirchhoff , Washington State University, USA Quinone Diffusion in Photosynthetic Membranes: Challenges Caused by Complex Membrane Architectures Carl E. Stafstrom , Johns Hopkins University, USA Ketogenic Diet: Evidence for Metabolic Control of Neuronal Excit- ability and Seizures Peter A. Crawford , University of Minnesota, USA Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Sig- naling, and Therapeutics Daniel P. Kelly , University of Pennsylvania, USA Ketone Bodies as a Therapeutic Strategy for Heart Failure Kieran Clarke , University of Oxford, United Kingdom Novel Ketone Monoester for Human Exercise and Cognition: Why, How, and When Eric Verdin , Buck Institute for Research on Aging, USA Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice Elena N. Dedkova , University of California - Davis, USA Ketone Bodies and their Polymers in Heart Failure and Type 2 Diabetes: Lessons Learned from the Ketone Ester Diet

Alessandra Cambi , Radboud University, The Netherlands Multimodal Microscopy Reveals Stiffness-dependent Nanoscale Remodeling of Different Actin Modules during Cell Protrusion Ralf Jungmann , Max Planck Institute of Biochemistry, Martinsried, Germany Superresolution Microscopy with DNA Molecules: Towards Local- izomics Luke Lavis , Janelia Research Campus, USA Building Brighter Fluorophores for Advanced Biological Imaging Bin Wu , Johns Hopkins University, USA Visualizing Translation Dynamics of Single mRNAs in Live Cells Don Lamb , Ludwig Maximilian University of Munich, Germany The Coming of Age: Fluorescence Investigations of the Early Child- hood of HIV Particles Elizabeth Hillman , Columbia University, USA High-speed, 3D, In Vivo Fluorescence Microscopy Biopolymers in Vivo Subgroup Chair: Simon Ebbinghaus , Technische Universität Braunschweig, Germany Speakers: James Bruce , University of Washington, USA Exploring the In Vivo Interactome

November 2018

November 2018

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T H E N E W S L E T T E R O F T H E B I O P H Y S I C A L S O C I E T Y

T H E N E W S L E T T E R O F T H E B I O P H Y S I C A L S O C I E T Y