Biophysical Society Bulletin | November 2020

Annual Meeting

Physical Cell Biology Subgroup Chair:   Melike Lakadamyali , University of Pennsylvania, USA. 2021 Program Chair: Johan Elf , Uppsala University, Sweden. Symposium Title: Mitochondrial and Metabolic Mechanisms of Lifespan and Healthspan Extension. Speakers: Naama Barkai , Weizmann Institute, Israel Disorder Region Guide Transcription Factor to Specific Genomic Sites

Long Cai , California Institute of Technology, USA Spatial Genomics in situ Analysis by seqFISH Nicholas Plachta , University of Pennsylvania, USA Imaging How Cells Choose their Fate, Shape, and Position to Form the Mammalian Embryo Aviv Regev , Broad Institute, USA Design for Inference and the Power of Random Experiments in Biology

Biophysical Society Thematic Meeting

Biophysics at the Dawn of Exascale Computers

Hamburg, Germany | May 24–28, 2021

Molecular biophysics over the next decade will be dominated by three technologies — electron microscopy and tomography, X-ray lasers, and machine learning. Taking us a step closer towards capturing bimolecular assemblies in action, these technol- ogies together with molecular simulations are delivering not only static structures, but movies of cellular functions. One com- mon denominator to this remarkable progress is the advent of graphics processor unit (GPU)-intensive compute resources over the past decade. Already leveraging parallel capabilities, areas of diffraction data and single-particle image processing, hybrid modeling, molecular dynamics and free-energy simulations, and drug design and discovery are frontrunners in leveraging the prowess of exascale computing. Fortuitously overlapping with the inception of the exascale era, this meeting will prepare the biophysics community to start advancing the development and implementation of computational algorithms towards the best use of the exascale computing resources. The meeting brings together experimentalists and theoreticians working in the broad areas of protein folding and assembly, dissection of allosteric pathways, macromolecular interactions and bottom-up structure of cells wherein the large- scale computing is expected to bring forth major discoveries. Molecular and cellular biologists, chemists, physicists, mathema- ticians, and computer scientists will find a common platform to share their innovations and future needs with experts, so as a community we move forward to best adapt ourselves with these world-class resources.

Abstract Submission Deadline: January 22, 2021

Early Registration Deadline: February 8, 2021

For more information, visit www.biophysics.org/2020Hamburg

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