Biophysical Society Conference | Tahoe 2022

Molecular Biophysics of Membranes

Daily Schedule

Session V

Ion Channels and Transporters Joseph Mindell, NINDS, NIH, USA, Chair

9:00 AM - 9:30 AM

Erkan Karakas, Vanderbilt University, USA Structural Basis for Activation and Gating of IP3 Receptor Calcium Channels Joseph Mindell, NINDS, NIH, USA Fat Chances: How a Signaling Lipid Influences Lysosomal pH Via the Chloride Transporter ClC-7

9:30 AM - 10:00 AM

10:00 AM - 10:30 AM

Emily Liman, University of Southern California, USA Structure and Function of the OTOP Proton Channels

10:30 AM - 10:45 AM

Coffee Break

Ballroom Pre-Function

10:45 AM - 11:15 AM

Randy Stockbridge, University of Michigan, USA Structural Determinants of Substrate Specificity in Small Multidrug Resistance Transporters Olive E. Burata, University of Michigan, USA * Elucidating the Substrate Specificities of the Two Major Functional Subtypes in the Small Multidrug Resistance (SMR) Family Huong T. Kratochvil, University of California, San Francisco, USA * Designed Proton Channels Reveal Mechanisms for Proton Channel Selectivity and Conductivity Jun Chen, Genentech, USA * TRPA1 – Biased Agonism and Structural Mechanisms of Modulation

11:15 AM - 11:30 AM

11:30 AM - 11:45 AM

11:45 AM - 12:00 PM

12:00 PM - 1:00 PM

Special-topic Hosted Lunch Table

Granhall/Garden Deck

Careers: Research in Biotech (Jun Chen, Genentech)

1:00 PM - 2:30 PM

Panel Discussion: Establishing Expectations and Benchmarks in Collaborations Between Experiment and Computation Panelists: Linda Columbus, Jessica Swanson, Syma Khalid, and Joseph Mindell

2:30 PM - 4:00 PM

Free Time

4:00 PM - 6:00 PM

Poster Session III

6:00 PM - 7:00 PM

Dinner

Granhall/Garden Deck

Session VI

Membrane Protein Dynamics Linda Columbus, University of Virginia, USA, Chair

7:00 PM - 7:30 PM

Linda Columbus, University of Virginia, USA Impact of Lipid-Membrane Protein Interactions on Membrane Protein Structure and Dynamics Jessica Swanson, The University of Utah, USA Kinetic Selection of Competing Ion Exchange Pathways: When Does the Electrical Versus Chemical Gradient Matter?

7:30 PM - 8:00 PM

6

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