Biophysical Society Conference | Tahoe 2023

Proton Reactions: From Basic Science to Biomedical Applications

Daily Schedule

10:00 AM – 10:30 AM

Keiichi Inoue, University of Tokyo, Japan The Role of Proton Transfer in Ion-Transporting Microbial Rhodopsins

10:30 AM – 10:50 AM

Coffee Break

Ballroom Pre-Function

Session III

The Hv1 Proton Channel Chair: Tom DeCoursey, Rush University Medical Center, USA Carlos L. Gonzalez, University of Miami, USA * Molecular Determinants of Voltage Sensor in CIHv1 Channel Francesco Tombola, University of California, Irvine, USA Pulling the Strings of Proton Conduction: Mechanical Regulation of Voltage-Gated Proton Channels Jana Shen, University of Maryland, USA Mechanism of pH Sensing in the Human Voltage-Gated Proton Channel Hv1 Ian Ramsey, Virginia Commonwealth University, USA Insights into the Structural Basis of pH-Dependent Gating and H + Permeation Mechanisms in the Hv1 Voltage-Gated Proton Channel Reactions at Membrane Interfaces Chair: Marylin Gunner, City College of New York, USA Balarama Sridhar Dwadasi, University of Calgary, Canada * Constant pH Molecular Dynamics Simulations of the Anion Exchanger-1 (AE1) Karen Fleming, Johns Hopkins University, USA Membrane Protein Thermodynamic Measurements Enabled by Protons Ana-Nicoleta Bondar, University of Bucharest, Romania Dynamic Hydrogen-Bond Networks for Proton Binding and Proton Transfer at Bio-Membrane Interfaces Thomas DeCoursey, Rush University Medical Center, USA Deciphering Apparent Cholesterol Effects on Voltage-Gated Proton Channels Lunch

10:50 AM – 11:00 AM

11:00AM – 11:30 AM

11:30 AM – 12:00 PM

12:00 PM – 12:30 PM

12:30 PM – 1:30 PM

Granhall/Garden Deck

Session IV

1:50 PM – 2:00 PM

2:00 PM – 2:30 PM

2:30 PM – 3:00 PM

3:00 PM – 3:30 PM

3:30 PM – 4:00 PM

Coffee Break

Ballroom Pre-Function

Session V

Mechanisms and Evolutionary Diversity of Molecular Proton Transporters Chair: Keiichi Inoue, Tokyo University, Japan

4:00 PM – 4:30 PM

Boris Musset, University of Nürenberg, Germany The Voltage-Gated Proton Channel Discovers its Family Marilyn Gunner, City College of New York, USA How the Multiplicity of Protonation States in Proteins Supports Proton Transfers

4:30 PM – 5:00 PM

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