Biophysical Society Thematic Meeting | Tutzing 2026

Single-Molecule FRET: The Next 30 Years

Daily Schedule

10:00 – 10:20

Chara Sarafoglou, Institute of Molecular Biology and Biotechnology, Heraklion, Crete, Greece* , PQ-ECA smFRET-Guided Integrative Biophysics Reveals Allosteric Modules as Energetic Control Points of Protein Free-Energy Landscapes

10:20 – 10:50

Coffee Break

Foyer

Session III

Application of FRET in Proteins Chair: Gillian Cadden, Aarhus University, Denmark

10:50 – 11:20

Emmanuel Margeat, CNRS-Montpellier, France Looking at Metabotropic Glutamate Receptors Dynamics with Single-Molecule FRET Ecenaz Bilgen, Ludwig Maximilian University of Munich, Germany* , PQ-ECA Exploring Dynamic Protein Systems with Single-Molecule FRET Catherine Ghosh, University of California, Merced, USA* , PQ-ECA The Speed Limit of Genomic Search: A Kinetic Race Between Electrostatic Steering, Sliding Friction, and Conformational Locking Elizabeth Rhoades, University of Pennsylvania, Philadelphia, USA* Phosphoregulation of Tau Function

11:20 – 11:40

11:40 – 12:00

12:00 – 12:20

12:20 – 14:00

Lunch

Restaurant Evangelische Akademie

Session IV

Method Development / Probes Chair: Line Lund, Aarhus University, Denmark

14:00 – 14:30

Scott Blanchard, St. Judes Children’s Research Hospital, USA Quantitative Investigations of Complex Molecular Machines Using smFRET: What We Have Learned and Where Are We Going Allison H. Squires, University of Chicago, USA Design and Differentiation of FRET Constructs – Easy as ABEL-PIE Thomas-Otavio Peulen, Technical University Dortmund, Germany* From Structure to Observables: Optimal Dye Models for Predicting Lifetimes, Anisotropies, and FRET

14:30 – 15:00

15:00 – 15:20

15:20 – 15:50

Coffee Break

Foyer

Session V

Method Development Chair: Claus Seidel, Heinrich Heine University Düsseldorf, Germany

15:50 – 16:20

Rainer Erdmann, PicoQuant GmbH, Germany smFRET in Industry – A 35-Year Journey

16:20 – 16:50

Karl-Heinz Drexhage Memorial Lecture Jörg Enderlein, Georg August University, Göttingen, Germany The Electrodynamics of Fluorescing Molecules: A Tribute to Karl-Heinz Drexhage Eitan Lerner, The Hebrew University of Jerusalem, Israel* The “Bliss” of Observing Single-Molecule Bursts from Clusters in Live Cell Biomolecular Condensate

16:50 – 17:10

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