Biophysical Society Thematic Meeting | Tutzing 2026

Single-Molecule FRET: The Next 30 Years

Daily Schedule

17:10 – 17:30

Quan Wang, NIH, Bethesda, MD, USA* Recent Developments of ABEL-FRET: Resolution Limits, Fast Dynamics and Biophysical Applications Mahran Shehade, Weizmann Institute of Science, Rehovot, Israel* , PQ-ECA Toward Understanding Structural Transitions and Dynamics in Proteins Using Plasmon-Enhanced smFRET Mirjam Kümmerlin, University of Oxford, United Kingdom* , PQ-ECA The Dark Side of FRET: Self-Quenching DNA Probes Enable Hour-Long smFRET and Live-Cell RNA Tracking

17:30 – 17:50

17:50 – 18:10

18:15 – 20:30

Poster Session

Seminarraum/Medienraum/Musiksaal

with Bavarian Brotzeit (Dinner) & Drinks

20:30 – 21:30

Parallel Round Table Discussions 1. FRET Standardization 2. FRET-Based Integrative Structural Biology 3. Women in FRET 4. Triggering Innovations in FRET

Room Assignments Made Onsite

Wednesday, September 23, 2026 8:30 – 18:00

Registration & Information

Foyer

Session VI

Application of FRET in Biochemistry Chair: Pooyeh Asadiatouei, Goethe University Frankfurt, Germany

9:00 – 9:45

Keynote Talk: Dagmar Klostermeier, University of Münster, Germany Deciphering the Mechanisms of Molecular Machines That Unwind and Untangle Nucleic Acids by Single-Molecule FRET: From Retrospective to Perspective Dina Grohman, University of Regensburg, Germany Single-Molecule Insights into the Dynamic Human RNA Interference Machinery Using SLAM-FRET Katherina Hemmen, University of Würzburg, Germany* Quantitative Image Spectroscopy for Protein-Protein Interactions in Living Cells: An Integrated FRET Framework

9:45 – 10:15

10:15 – 10:35

10:35 – 11:00

Coffee Break

Foyer

Session VI I

FRET in Cellular Experiments Chair: Jacob Piehler, Osnabrück University, Germany Thorsten Hugel, University of Freiburg, Germany* Single-Molecule FRET Trajectories in Living Cells

11:00 – 11:20

11:20 – 11:40

Sharonda LeBlanc, North Carolina State University, Raleigh, NC, USA* Live-Cell Flim-FRET Reveals Dynamic ATPase-Driven Pre-Ribosome Remodeling States

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