Program Book

2631-P os B oard #B323 PROBING EPHA2 SIGNALLING IN THE CONTEXT OF INTEGRIN ADHESION USING A HYBRID OF FLUID LIPID BILAYERS AND IMMOBILIZED RGD PATTERNS. Zhongwen Chen , Cheng-Han Yu, Kabir H. Biswas, Ronen Zaidel-Bar, Jay T. Groves 2632-P os B oard #B324 SINGLE MOLECULE MEASUREMENTS OF TCR TRIGGERING IN SELF-REACTIVE T CELLS. Katherine N. Alfieri , Jay T. Groves 2633-P os B oard #B325 BIOPHYSICAL PROPERTIES OF IMMUNE RECEPTOR PROTEINS AT THE MEMBRANE INTERFACE. Daniel R. Scott , C. Alejandro Velikovsky, Roy A. Mariuzza, John P. Marino, Susan Krueger, Hirsh Nanda 2634-P os B oard #B326 DYNAMIC BEHAVIOR OF TCR MICROCLUSTERS ON A LIVE CELL INVESTIGATED BY A GOLD NANOPARTICLE ARRAY. Hiroyuki Kai , Nina Caculitan, Eulanca Liu, Nicole Fay, Yan Yu, Theobald Lohmüller, Jay T. Groves 2635-P os B oard #B327 INVESTIGATION OF TCR TRIGGERING MECHANISM WITH MEMBRANE ANCHORED FAB’ FRAGMENTS. Michael P. Coyle , Geoffrey P. O’Donoghue, Rafal M. Pielak, Jenny J. Lin, Jay T. Groves 2636-P os B oard #B328 T CELL COSTIMULATORY RESPONSE AND RECEPTOR DYNAMICS DETERMINED BY LIGAND ENGAGEMENT. Nicole C. Fay , Katherine Alfieri, Hiro Kai, Jay Groves 2637-P os B oard #B329 FC ε RI SIGNAL PROPAGATION IS REGULATED THROUGH TRANSIENT BINDING OF SYK. Samantha L. Schwartz , Cheryl A. Telmer, Mara P. Steinkamp, Marcel P. Bruchez, Keith A. Lidke, Diane S. Lidke 2638-P os B oard #B330 SHEAR FLOW REGULATES OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL STEM CELLS THROUGHTRPM7-MEDIATED OSTERIX PATHWAY. Yi-Shiuan Liu , Chin-Ching Huang, Meng-Hua Yen, Oscar K. Lee 2639-P os B oard #B331 PROFILING OF TARGET GENES THAT REGULATE EP-INDUCED GROWTH INHIBITION OF H460 THROUGH THE TRANSCRIPTIONAL AND PROTEOMIC ANALYSIS. Joonhee Kim , Eunil Lee, Eunjeong Cha, Eunyoung Hong 2640-P os B oard #B332 ACTIVE PATTERNING OF CELL SURFACE MOLECULES FROM NANOSCALE CLUSTERS TO MESOSCALE MEMBRANE MOSAICS DICTATED BY DYNAMIC ACTIN. Suvrajit Saha , Amit Das, Anirban Polley, Madan Rao, Satyajit Mayor 2641-P os B oard #B333 CORTICAL MICROTUBULES SHAPE GPCR SPATIOTEMPORAL MEMBRANE ORGANIZATION AND SIGNALING. Alessandra Cambi 2642-P os B oard #B334 NANOARCHITECTURE OF INTEGRIN RECEPTOR CLUSTERS ON VERY SOFT SUBSTRATES. Rishita Changede , Felix Margadant, Michael P. Sheetz 2643-P os B oard #B335 ALLOSTERIC REGULATION BY COMPONENTS OF A CRITICAL MEMBRANE. Benjamin B. Machta

2644-P os B oard #B336 EXCITABILITY OF GUANYLATE CYCLASE SIGNALING PATHWAY MEDIATING CHEMOTAXIS. Yuki Tanabe , Masahiro Ueda 2645-P os B oard #B337 INVESTIGATING PHOSPHATIDYLINOSITOL 3,4-BISPHOSPHATE 3-PHOSPHATASE ACTIVITY OF CI-VSP IN XENOPUS LAEVIS OOCYTES AND CHO CELLS USING FLUORESCENT PHOSPHOINOSITIDE PROBES. Svenja Mertelmeyer, Angeliki Mavrantoni, Dominik Oliver, Christian R. Halaszovich 2646-P os B oard #B338 international travel awardee IN-SITU DESCRIPTION OF THE ROLE OF PTDINS(3,4,5)P 3 AND PTDSER ON PDK1 REGULATION IN HUMAN CANCER CELLS BY ADVANCED QUANTITATIVE MICROSCOPY. Gloria de las Heras , Veronique Calleja, Banafshe Larijani, Jose Requejo-Isidro 2647-P os B oard #B339 HER2 OVEREXPRESSION INDUCES MEMBRANE DEFORMATION THAT INCREASES CELL MOTILITY. Inhee Chung , Mike Reichelt, Don Dowbenko, Ira Mellman, Mark Sliwkowski 2648-P os B oard #B340 CD44-BASED ADHESION AND MECHANOTRANSDUCTIVE SIGNALINGON ENGINEEREDHYALURONIC ACIDMATRICES. Yushan Kim , Sanjay Kumar 2649-P os B oard #B341 REGULATION OF THE HER3/ERBB3 PSEUDOKINASE DOMAIN BY AN ATP-COMPETITIVE INHIBITOR. Peter Littlefield, Mark M. Moasser, Natalia Jura 2650-P os B oard #B342 ARCHAZOLID-B PROVIDES ALTERNATIVE THERAPY FOR TRASTUZUMAB-RESISTANT ERBB2 POSITIVE BREAST CANCER. Tamás Lajtos , László Simon, Angelika M. Vollmar, János Szöllősi, György Vereb Exocytosis and Endocytosis II (Boards #B343-#B359) 2651-P os B oard #B343 RESCUE OF DOPAMINE RELEASE AND BEHAVIOR BY TRANSPLANTED NEURAL STEM CELLS IN A RAT MODEL OF PARKINSONISM. Xinjiang Kang, Huadong Xu, Li Zhou, Panli Zuo, Zijun Deng, Bing Liu, Bin Liu, Li Wang, Haiqian Dou, Feipeng Zhu, Changhe Wang, Shirong Wang, Wenlin Li, Kang Zhang, Zhuan Zhou 2652-P os B oard #B344 FISB MEDIATED MEMBRANE FISSION DURING SPORULATION IN BACILLUS SUBTILIS. Martha Braun , Christopher Daniel Rodrigues, Thierry Doan, Jeff Coleman, David Rudner, Erdem Karatekin 2653-P os B oard #B345 FRET BASEDTHERMODYNAMICS AND KINETICS INVESTIGATIONOF ENDOPHILINDIMERIZATION. Zhiming Chen , Ken Chang, Benjamin R. Capraro, Chih-Jung Hsu, Tobias Baumgart 2654-P os B oard #B346 ENDOPHILIN RAPIDLY BENDS MEMBRANES TO PROMOTE ENDOCYTOSIS. Kumud R. Poudel , Jihong Bai 2655-P os B oard #B347 ENDOCYTOSIS OF LIPOSOMES CONTAINING SULFO- CEREBROSIDES BY AN ASTROCYTOMAL CELL LINE: IS IT A CHARGE MEDIATED PROCESS OR DOES IT INVOLVE A SPECIFIC RECEPTOR? Elizabeth Suesca , Nathalia Bustamante, Natalia Bolaños, John Mario González, Chad Leidy

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Biophysical Society 58 th Annual Meeting, San Francisco, California