Program Book

2976-P os B oard #B668 INTERPROTEIN ELECTRON TRANSFER WITH PROTEIN MAQUETTES. Bryan A. Fry , Geetha Goparaju, Christopher M. Moser, P Leslie Dutton, Bohdana M. Discher 2977-P os B oard #B669 QUANTUM DELOCALIZATION OF PROTONS IN THE KETOSTEROID ISOMERASE ACTIVE SITE. Lu Wang , Stephen D. Fried, Yufan Wu, Steven G. Boxer, Thomas E. Markland 2978-P os B oard #B670 FEMTOSECOND 2D-IR SPECTROELECTROCHEMISTRY OF BIOMOLECULES. Youssef El Khoury , Luuk, J.G., W VanWilderen, Jens Bredenbeck 2979-P os B oard #B671 MODELING H-BONDING AND PROTONATION STATES OF MEMBRANE BURIED ARG-TYR PAIRS. Andrew Banyikwa , Alan G. Goos, Mark S. Braiman 2980-P os B oard #B672 ROLES FOR PROTONS IN LIVING MEMBRANES: CARDIOLIPIN. Thomas Haines Mitochondria in Cell Life and Death II (Boards #B673–#B688) 2981-P os B oard #B673 INVESTIGATING TOM40 STRUCTURE AND FUNCTION RELATIONSHIP USING SINGLE CHANNEL ANALYSIS. Daniel Jacobs, Adam J. Kuszak, Susan K. Buchanan, Sergey M. Bezrukov, Tatiana K. Rostovtseva, Philip A. Gurnev 2982-P os B oard #B674 ALPHA-SYNUCLEIN INDUCES MITOCHONDRIAL DYSFUNCTION LEADING TO A HIGHER SUSCEPTIBILITY OF PTP OPENING. Marthe HR Ludtmann , Plamena R. Angelova, Sonia Gandhi, David Kleneman, Michael Devine, Nicholas W. Wood, Andrey Y. Abramov 2983-P os B oard #B675 FUNCTIONAL, STRUCTURAL, AND COMPUTATIONAL APPROACHES TO THE MOLECULAR MECHANISM OF VDAC GATING. Oscar Teijido Hermida , Sergei Yu Noskov, Rachna Ujwal, Jeff Abramson, Matthew T. Eddy, Robert G. Griffin, Sergey M. Bezrukov, Tatiana K. Rostovtseva 2984-P os B oard #B676 PARKINSON DISEASE-ASSOCIATED PROTEIN ALPHA- SYNUCLEIN BLOCKS VDAC PROVIDING NEW INSIGHTS INTO MITOCHONDRIAL TOXICITY. Tatiana K. Rostovtseva , Philip A. Gurnev, Thai Leong Yap, Jennifer C. Lee, Sergey M. Bezrukov 2985-P os B oard #B677 ANTAGONISTS OF THE INHIBITORY EFFECT OF FREE TUBULIN ON VDAC INDUCE OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION. David N. DeHart, Monika Gooz, Tatiana K. Rostovtseva, Kely L. Sheldon, John J. Lemasters, Eduardo N. Maldonado 2986-P os B oard #B678 TRANSIENT MITOCHONDRIAL PERMEABILITY TRANSITION PORE OPENING IN CARDIAC MYOCYTES DURING SR CA RELEASE. Xiyuan Lu , Donald Bers

2987-P os B oard #B679 SPERMINE SELECTIVELY INHIBITS HIGH-CONDUCTANCE BUT NOT LOW-CONDUCTANCE MODE OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (MPTP). Pia A. Elustondo , Evgeny V. Pavlov 2988-P os B oard #B680 CONTROL OF MITOCHONDRIAL CA 2+ UPTAKE THRESHOLD VIA THE MICU1:MCU RATIO. Tünde Golenár, György Csordás , Gergő Szanda, Cynthia Moffat, Erin L. Seifert, András Spät, György Hajnóczky 2989-P os B oard #B681 REGULATION OF MITOCHONDRIAL OUTER AND INNER MEMBRANE FUSION COUPLING. David Weaver , Xingguo Liu, Gyorgy Hajnoczky 2990-P os B oard #B682 MITOCHONDRIAL DYNAMICS IN NEONATAL AND ADULT CARDIOMYOCYTES. Veronica Eisner , Ryan Cupo, Csordas Gyorgy, Lan Cheng, Walter Koch, Gyorgy Hajnoczky 2991-P os B oard #B683 PURINE NUCLEOTIDES SIMILARLY REGULATE UNCOUPLING PROTEIN 3 AND 1. Gabriel Pürstinger , Anne Rupprecht, Melanie Köhler, Peter Hinterdorfer, Elena E. Pohl 2992-P os B oard #B684 QUANTIFICATION OF MITOCHONDRIAL UCP3 EXPRESSION IN MOUSE TISSUES. Karolina E. Hilse , Anne Rupprecht, Anastasia Kalinovich, Irina G. Shabalina, Elena E. Pohl 2993-P os B oard #B685 MITOCHONDRIAL UNCOUPLING AND THERMOGENESIS IN BEIGE FAT. Ambre M. Bertholet 2994-P os B oard #B686 UCP2 OVEREXPRESSION WORSENS MITOCHONDRIAL DYSFUNCTION AND ACCELERATES DISEASE PROGRESSION IN A MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS. Pablo M. Peixoto , Hyun-Jeong Kim, Giovanni Manfredi 2995-P os B oard #B687 UCP2 MODULATES MITOCHONDRIAL CALCIUM UNIPORT- ER. Lukas Jaroslaw Motloch , Robert Larbig, Tina Gebing, Sara Reda, Stephanie Weichselbaumer, Daniela Kokoschinegg, Astrid Schwaiger, Martin Wolny, Uta C. Hoppe 2996-P os B oard #B688 UCP2 MODULATES CELLULAR EXCITATION CONTRACTION COUPLING VIA MITOCHONDRIAL CALCIUM UPTAKE. Robert K. Larbig, Lukas J. Motloch, Tina Gebing, Sara Reda, Eva Deininger, Astrid Schwaiger, Martin Wolny, Uta C. Hoppe  Cellular Pathways and Networks: Prokaryotic and Eukaryotic (Boards #B689–#B705) 2997-P os B oard #B689 REGULATORY FEEDBACK PROGRAMS IN THE APOPTOTIC DECISION-MAKING OF HER2-POSITIVE BREAST CANCER CELLS IN RESPONSE TO HER2 INHIBITION. Christina Sutera, Mercedes A. Duran-Paez, Elizabeth Haughney, Azad Gucwa, Marc R. Birtwistle, Marc Y. Fink

T U

E S

D A Y

157

Biophysical Society 58 th Annual Meeting, San Francisco, California