Program Book

3520-P os B oard #B248 SYNCHRONOUS OPTICAL AND ELECTRICAL MEASUREMENTS OF SINGLE DNA MOLECULES TRANSLOCATING THROUGH A SOLID STATE NANOPORE. Jose A. Bustamante , Nick Yelle, Tabard-Cossa Vincent 3521-P os B oard #B249 DNA DENATURATION-SUPERCOILING TRANSITION AT THERMOPHILIC TEMPERATURES. Eric Galburt , Eric Tomko, Tom Stump, Ana Ruiz Manzano 3522-P os B oard #B250 IN SITU STRUCTURE AND DYNAMICS OF DNA ORIGAMI DETERMINED THROUGH MOLECULAR DYNAMICS SIMULATIONS. Jejoong Yoo , Aleksei Aksimentiev Protein-Nucleic Acid Interactions III (Boards #B251–#B273) 3523-P os B oard #B251 TARGET RECOGNITION AND DEGRADATION BY AN ADAPTIVE BACTERIAL IMMUNE SYSTEM. Megan L. Hochstrasser , David W. Taylor, Prashant Bhat, Chantal K. Guegler, Jennifer A. Doudna 3524-P os B oard #B252 DNA INTERROGATION BY THE CRISPR RNA-GUIDED ENDONUCLEASE CAS9. Samuel H. Sternberg , Sy Redding, Martin Jinek, Eric C. Greene, Jennifer A. Doudna 3525-P os B oard #B253 STRUCTURAL BASIS FOR FOREIGN DNA INTEGRATION IN CRISPR ADAPTIVE IMMUNITY. James K. Nunez , Jennifer A. Doudna 3526-P os B oard #B254 education travel awardee A BIOPHYSICAL STUDY OF THE G-QUADRUPLEX-INSULIN INTERACTION. Nicole L. Michmerhuizen , Margaret A. Van Winkle, Kumar Sinniah 3527-P os B oard #B255 ADAR2: TOWARDS A STRUCTURAL AND KINETIC UNDERSTANDING OF RNA EDITING. Andrew D. Kehr , Mark R. Macbeth, Gordon S. Rule 3528-P os B oard #B256 ACTIVATION OF PKR BY STEM-LOOP RNAS WITH FLANKING SSRNA TAILS. Christopher B. Mayo , C. Jason Wong, James L. Cole 3529-P os B oard #B257 DOUBLE-STRAND RNA BINDING PROTEIN PROFILING. Xinlei Wang 3530-P os B oard #B258 THERMODYNAMIC AND STRUCTURAL STUDIES OF PDX1 BINDING TO ELEMENTS FROM NATURAL PROMOTERS AND NEAR-CONSENSUS SITES. Monique Bastidas , Scott A. Showalter 3531-P os B oard #B259 ANALYSIS OF PKR DIMERIZATION BY RESONANCE ENERGY TRANSFER. Bushra Husain , Michael Bruno, James L. Cole 3532-P os B oard #B260 MECHANISMS OF TRF1/TRF2 BINDING PROPERTIES AND DNA SEQUENCE RECOGNITION AS STUDIED BY MOLECULAR DYNAMICS. Milosz Wieczor , Pawel Wityk, Adrian Tobiszewski, Jacek Czub

3533-P os B oard #B261 STATISTICAL THERMODYNAMICS FOR BINDING OF AN RNA APTAMER AND A PARTIAL PEPTIDE OF A PRION PROTEIN. Tomohiko Hayashi , Hiraku Oshima, Tsukasa Mashima, Takashi Nagata, Masato Katahira, Masahiro Kinoshita 3534-P os B oard #B262 cpow travel awardee HOT-SPOTS DETECTION - APPLICATION TO A VARIETY OF DIFFERENT PROTEIN-BASED SYSTEMS. Rui Ramos, Joao Martins, Antonio Pimenta, Irina Moreira 3535-P os B oard #B263 STRUCTURAL DESIGN AND VALIDATION OF LINKERS FOR ZINC FINGER PROTEINS. Priya Anand , Alexander Schug, Wolfgang Wenzel 3536-P os B oard #B264 THE INCREASED AFFINITY AND DECREASED SELECTIVITY OF THE HPV6 E2 ΔLL MUTANT STEMS FROM A DECREASE IN DNA BENDING IN THE MUTANT COMPLEX. Geoffrey M. Gray , Arjan van der Vaart 3537-P os B oard #B265 SINGLE-MOLECULE VIEW ON THE DUALITY OF MICRORNA URIDYLATION. Luuk Loeff , Minju Ha, Boseon Kim, Kyu-Hyeon Yeom, Dhirendra K. Simanshu, Dinshaw J. Patel, Narry V. Kim, Chirlmin Joo 3538-P os B oard #B266 SINGLE MOLECULE DNA STRETCHING STUDIES OF DNA INTERCALATION. Ioulia Rouzina 3539-P os B oard #B267 NUCLEIC ACID BINDING KINETICS OF HIV-1 NUCLEOCAPSID PROTEINS FROM SINGLE MOLECULE DNA STRETCHING. Jialin Li , Robert Gorelick, Ioulia Rouzina, Mark Williams 3540-P os B oard #B268 PARTIAL UNWRAPPING OF SSB FROM SSDNA FACILITATES RECA FILAMENT FORMATION. Sukrit Suksombat , Alexander G. Kozlov, Timothy M. Lohman, Yann R. Chemla 3541-P os B oard #B269 THE FORCE DEPENDENT PROTEIN-DNA STRUCTURE OF H-NS. Samuel Yoshua , Haowei Wang, Nanak Singh, Josh Milstein 3542-P os B oard #B270 ENZYMATIC REACTIONS IN NANO-CONFINED DNA MONOLAYERS. Pietro Parisse , Chiara Rotella, Jashmini Deka, Matteo Castronovo, Giacinto Scoles, Loredana Casalis 3543-P os B oard #B271 SNAP: SOFTWARE FOR ANALYZING STRUCTURES OF NUCLEIC ACID-PROTEIN COMPLEXES. Xiang-Jun Lu , Wilma K. Olson, Harmen J. Bussemaker 3544-P os B oard #B272 A PROTEIN-RNA KNOWLEDGE-BASED POTENTIAL FOR SCORING AND REFINEMENT. Adelene YL Sim , Adrien Guilhot-Gaudeffroy, Chandra Verma, Peter Minary, Julie Bernauer 3545-P os B oard #B273 ON-CHIP ANALYSIS OF INTERMITTENT MOLECULAR ENCOUNTERS IN NUCLEASE DIGESTION OF SPECIFIC DNA SEQUENCE. Daisuke Onoshima , Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

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Biophysical Society 58 th Annual Meeting, San Francisco, California