Program Book

3814-P os B oard #B542 EFFECTS OF TRPM7 INHIBITORS ON PHYSIOLOGICAL MG 2+ INFLUX IN RAT VENTRICULAR MYOCYTES. Michiko Tashiro , Hana Inoue, Masato Konishi 3815-P os B oard #B543 LOCALIZATION AND ROLE OF TRANSIENT RECEPTOR POTENTIAL CATION CHANNELS IN RABBIT VENTRICULAR MYOCYTES. Qinghua Hu, McNary G. Thomas, Frank B. Sachse 3816-P os B oard #B544 SINGLE MOLECULE OPTICAL RECORDINGS OF TRPV1 MOBILITY AND ACTIVITY. Eric Senning , Sharona E. Gordon 3817-P os B oard #B545 TRPC3 MODULATES ASSOCIATION OF ORAI1 WITH IMMUNOPHILIN FKBP12 AND ORAI-MEDIATED CA 2+ - TRANSCRIPTION COUPLING IN MAST CELLS. Michael Poteser , Bernhard Doleschal, Michaela Schernthaner, Hannes Schleifer, Katrin Tieber, Irene Frischauf, Christoph Romanain, Klaus Groschner 3818-P os B oard #B546 CA 2+ FACILITATES TRPC4 ACTIVATION BY GI/O SIGNALING IN BOTH CALMODULIN DEPENDENT AND INDEPENDENT MANNER. Dhananjay Thakur , Michael X. Zhu 3819-P os B oard #B547 EXPLORING THE ARCHITECTURE OF THE OUTER PORE OF THE TRPV1 CHANNEL WITH DOUBLE-KNOT TOXIN. Andrés Jara-Oseguera , Chanhyung Bae, Feng Zhang, Tsg-Hui Chang, Jae Il Kim, Kenton J. Swartz 3820-P os B oard #B548 ALLOSTERIC COUPLING AND THERMAL ACTIVATION IN TRP CHANNELS. Leon D. Islas , Andres Jara-Oseguera 3821-P os B oard #B549 TOWARD THE MECHANISM OF CAPSAICIN BINDING TO TRPV1 IN A LIPID BILAYER VIA ATOMISTIC SIMULATION. Sonya M. Hanson , Simon Newstead, Kenton J. Swartz, Mark S.P. Sansom 3822-P os B oard #B550 BIOPHYSICAL CHARACTERIZATION OF THE TRPM8 VOLTAGE-SENSING DOMAIN. Wade D. Van Horn , Parthasarathi Rath, Nicholas Sisco 3823-P os B oard #B551 CRYSTAL STRUCTURE OF THE N-TERMINAL ANKYRIN REPEAT DOMAINOFTRPV3 REVEALS UNIQUE CONFORMATION OF FINGER 3 LOOP CRITICAL FOR CHANNEL FUNCTION. Di-Jing Shi, Sheng Ye, Xu Cao, Rongguang Zhang, KeWei Wang 3824-P os B oard #B552 A STRUCTURAL FRAMEWORK FOR THE POLYMODAL PAIN SENSOR TRPV1. Fan Yang , Vladimir Yarov-Yarovoy, Jie Zheng 3825-P os B oard #B553 CONFORMATIONAL PLASTICITY OF TRPV1 ANKYRIN REPEAT DOMAIN IN COMPLEX WITH CYSTEINE REACTIVE AGONIST ALLICIN. Ernesto Ladron de Guevara , Jorge Romero-Estrada, Margarita Romero-Avila, Gisela Rangel, Leon D. Islas 3826-P os B oard #B554 minority affairs travel awardee REGULATION OF TRPV1 BY PHOSPHOINOSITIDES AND OTHER NEGATIVELY CHARGED LIPIDS. Jan-Michael Rives , Viktor Lukacs, Xiaohui Sun, Eleonora Zakharian, Tibor Rohacs

3801-P os B oard #B529 MODULATION OF THE VOLTAGE-GATED PROTON CHANNEL HV1 BY SMALL GATING-MODIFIER LIGANDS. Bosmat Refaeli , Polina Kornilov, Asher Peretz, Bernard Attali 3802-P os B oard #B530 ROLE OF A PH SENSITIVE SITE IN ENAC NA + SELF-INHIBITION. Ossama B. Kashlan , Brandon M. Blobner, Zachary Zuzek, Michael A. Tolino, Thomas R. Kleyman 3803-P os B oard #B531 VDAC-KINASE ELECTROGENIC COMPLEXES AS DIRECT GENERATORS OF MITOCHONDRIAL MEMBRANE POTENTIALS. Victor V. Lemeshko 3804-P os B oard #B532 CHARACTERIZATIONOFTHE INTRINSIC VOLTAGE-DEPENDENT GATING MECHANISM OF CALHM ION CHANNELS. Jessica Tanis , Zhongming Ma, J. Kevin Foskett 3805-P os B oard #B533 NAVIGATINGTHE TERRA INCOGNITA OF MALE FERTILITY: SPERM ION CHANNELS ANDTHEIR FUNCTION. Polina V. Lishko , Melissa R. Miller, Nadja Mannowetz, Natasha M. Naidoo, Seung-A S. Choo, James F. Smith 3806-P os B oard #B534 INITIAL FUNCTIONAL AND STRUCTURAL ANALYSIS OF PLANT MECHANOSENSITIVE CHANNEL MSL10. Grigory Maksaev , Kira Veley, Elizabeth Haswell  TRP Channels II (Boards #B535–#B557) 3807-P os B oard #B535 ROLE OF POLYPHOSPHATE IN CANCER CELL PROLIFERATION. Lusine Demirkhanyan , Pia Elustondo, Evgeny Pavlov, Eleonora Zakharian 3808-P os B oard #B536 UPREGULATION OF TRPM7-LIKE CURRENT IN ISCHEMIA DAMAGED HUMAN ATRIAL CARDIOMYOCYTES. Mante Almanaityte , Irma Martisiene, Vida Gendviliene, Regina Macianskiene 3809-P os B oard #B537 DEVELOPMENT OF TRPC ASSAYS ON AUTOMATED ELECTROPHYSIOLOGY PLATFORMS. Mark J. McPate , Gurdip Bhalay, Sian Fairbrother, Martin Gosling, Paul J. Groot-Kormelink, Rebecca Lane, Toby Kent, Michiel Van Diepen, J. Martin Verkuyl, Pamela Tranter 3810-P os B oard #B538 A NEW CLASS OF ANALGESICS EXERTS A DUAL MODULATION ON TRPA1 AND TRPV1 CHANNELS. Roberta Gualdani , Oscar Francesconi, Barbara Richichi, Maria Rosa Moncelli 3811-P os B oard #B539 TRPM3 - A PROMISINGTARGET FOR ANALGESICTREATMENT. Katharina Held , Sílvia João Pinto, Sara Kerselaers, Katrien De Clercq, Patrick Chaltin, Thomas Voets, Joris Vriens 3812-P os B oard #B540 EXTRACELLULAR LOOPS ARE ESSENTIAL FOR THE ASSEMBLY AND FUNCTIONOFTRPP/PKD COMPLEXES. Zahra Salehi-Najafabadi, Clarissa Lam, G M Mahmud Arif Pavel, Parul Kashyap, Yong Yu 3813-P os B oard #B541 NICOTINIC ACID ACTIVATES THE CAPSAICIN RECEPTOR TRPV1 - A POTENTIAL MECHANISM FOR CUTANEOUS FLUSHING. Linlin Ma , Bo Hyun Lee, Rongrong Mao, Anping Cai, Yunfang Jia, Heather Clifton, Saul Schaefer, Lin Xu, Jie Zheng

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Biophysical Society 58 th Annual Meeting, San Francisco, California