Program Book

772-P os B oard #B527 cpow travel awardee DIFFERENTIAL EFFECTS OF SYNAPTIC AND EXTRASYNAPTIC NMDA RECEPTORS ON A β -INDUCED NITRIC OXIDE PRODUCTION IN CEREBROCORTICAL NEURONS. Elena Molokanova , Mohd Waseem Akhtar, Sara Sanz-Blasco, Tomohiro Nakamura, Shu-Ichi Okamoto, Shichun Tu, Juan C. Piña-Crespo, Scott R. McKercher, Stuart A. Lipton 773-P os B oard #B528 INTER-SUBUNIT INTERACTIONS OF NMDA RECEPTOR AMINO-TERMINAL DOMAINS ASSOCIATED WITH ALLOSTERIC MODULATION. Rita E. Sirrieh , David M. MacLean, Vasanthi Jayaraman 774-P os B oard #B529 PROTON MEDIATED CONFORMATIONAL CHANGES IN ACID SENSING ION CHANNEL1A. Swarna S. Ramaswamy , David M. MacLean, Alemayehu A. Gorfe, Vasanthi Jayaraman 775-P os B oard #B530 INTERSUBUNIT SALT-BRIDGE FORMATION DURING GATING OF RASIC1A. Katrin Augustinowski , Stefan Gruender 776-P os B oard #B531 FINGER-THUMB INTERDOMAIN INTERACTIONS INFLUENCE ASIC1A PROTON ACTIVATION. Aram J. Krauson , Marcelo D. Carattino 777-P os B oard #B532 MODULATION OF CHICKEN ASIC1 BY 2-GUANIDINE- 4-METHYLQUINAZOLINE (GMQ) IN THE ABSENCE AND PRESENCE OF PSALMOTOXIN-1. Rachel N. Johnson , Eric B. Gonzales 778-P os B oard #B533 SIGNAL TRANSMISSION WITHIN THE TRIMERIC P2X2 RECEPTOR UPON VOLTAGE- AND [ATP]- DEPENDENT GATING. Batu Keceli , Yoshihiro Kubo 779-P os B oard #B534 SUBTYPE-SPECIFIC CONTROL OF P2X RECEPTOR SIGNALING BY ATP AND MAGNESIUM. Mufeng Li , Emily Harnish, Shai D. Silberberg, Kenton J. Swartz 780-P os B oard #B535 FUNCTION OF THE SECOND TRANSMEMBRANE DOMAIN OF THE HUMAN P2X7 RECEPTOR. Fritz Markwardt , Anja Pippel, Michaela Stolz, Tanemasa Rahn, Günther Schmalzing 781-P os B oard #B536 THE SECOND TRANSMEMBRANE DOMAIN AND ADJACENT AMINO ACIDS DETERMINE APPARENT LIGAND AFFINITY OF A PEPTIDE-GATED HYDRA SODIUM CHANNEL (HYNAC). Marc C. Assmann , Stefan Dürrnagel, Anne Kuhn, Michael B. Schultz, Thomas W. Holstein, Stefan Gründer 782-P os B oard #B537 MOLECULAR MECHANISM OF LUNG OEDEMA CLEARANCE BY AP301: DEPENDENCE OF ENAC PORE FORMING SUBUNITS. Waheed Shabbir , Prastoo Hazemz-Scherbaum, Rosa Lemmens-Gruber 783-P os B oard #B538 PROTON-DEPENDENT CONFORMATIONAL DYNAMICS IN KCSA. Dorothy M. Kim , Igor Dikiy, David Posson, David Eliezer, Crina M. Nimigean

784-P os B oard #B539 CHARGED RESIDUES ON THE INTRACELLULAR INTERSUBUNIT ASSEMBLY INTERFACE CONTRIBUTE TO CALCIUM-SENSITIVITY OF BK CHANNELS. Yingxin Li, Hao-Min Pan, Qin Li, Ha Rim Kwak, Jiusheng Yan 785-P os B oard #B540 FUNCTIONAL IMPLICATIONS OF ALTERNATIVE SPLICING IN THE CALCIUM-ACTIVATED BK CHANNEL IN THE AMPULLA OF LORENZINI OF THE SKATE. Benjamin King, Ling-Fang Shi, Peter Kao, William T. Clusin 786-P os B oard #B541 STRUCTURAL AND THERMODYNAMIC CHARACTERIZATION OF THE GATING PATHWAY IN A K+ CHANNEL. Murali K. Bollepalli, Philip W. Fowler, Markus Rapedius, Lijun Shang, Mark S. P. Sansom, Stephen J. Tucker, Thomas Baukrowitz 787-P os B oard #B542 HCN C-TERMINAL REGION SPEEDS ACTIVATION INDEPENDENTLY OF AUTOINHIBITION. Kaylee E. A. Magee , Edgar C. Young 788-P os B oard #B543 LIPID MODULATION OF A DUAL FUNCTION TMEM16 CHANNEL/SCRAMBLASE. Mattia Malvezzi , Radmila Janjusevic, Anant Menon, Alessio Accardi 789-P os B oard #B544 YIDC ALTERS CONDUCTIVITY AND ION SELECTIVITY OF THE BACTERIAL TRANSLOCATION CHANNEL SECYEG. Lukas Winter , Denis Knyazev, Nicole Ollinger, Andreas Vogt, Christine Siligan, Hans Gerorg Koch, Peter Pohl Muscle: Fiber and Molecular Mechanics and Structure I (Boards #B545–#B576) 790-P os B oard #B545 THE MYOSIN START-OF-POWER STROKE STATE AND HOW ACTIN BINDING DRIVES THE POWER STROKE. Matthias Preller , Kenneth C. Holmes 791-P os B oard #B546 THE MYOSIN INHIBITOR BLEBBISTATIN STABILIZES THE SUPER-RELAXED STATE IN SKELETAL MUSCLE. Clyde Wilson, Nariman Naber, Edward Pate, Roger Cooke 792-P os B oard #B547 ATTACHED MOLECULAR MOTOR IN TRAPPED SINGLE MOLECULE ASSAY AS A BI-DIMENSIONAL BROWNIAN MULTI-STABLE SYSTEM. Lorenzo Marcucci , Toshio Yanagida 793-P os B oard #B548 DIRECT OBSERVATION OF PHOSPHATE INHIBITING THE FORCE-GENERATING CAPACITY OF A MINI-ENSEMBLE OF MYOSIN MOLECULES. Sam Walcott, Matthew Turner, Mike Woodward, Edward P. Debold 794-P os B oard #B549 UNDERSTANDING THE EFFECTS OF CARDIOMYOPATHY CAUSING MUTATIONS ON HUMAN BETA CARDIAC MYOSIN BIOMECHANICAL FUNCTION. Suman Nag , Ruth Sommese, Jongmin Sung, Elizabeth Choe, Masataka Kawana, Carol Cho, Rebecca Taylor, Chao Liu, Shirley Sutton, Kathleen Ruppel, James Spudich

F R I D A Y

S A T U R D A Y U N D A Y

49

Biophysical Society 58 th Annual Meeting, San Francisco, California