Program Book

1295-P os B oard #B25 STRUCTURAL DIFFERENCES BETWEEN THE CLOSED AND OPEN STATES OF CHANNELRHODOPSIN-2 AS OBSERVED BY EPR SPECTROSCOPY. Nils Krause , Christopher Engelhard, Joachim Heberle, Ramona Schlesinger, Robert Bittl 1296-P os B oard #B26 ASSESSING THE TRANSPORT MECHANISM OF NEUROTRANS- MITTER SODIUM SYMPORTER PROTEINS WITH MOLECULAR DYNAMICS. Emily Benner , Marco J. Acevedo, Jeffry D. Madura  Protein Folding and Unfolding (Boards #B27–#B56) 1297-P os B oard #B27 SEQUENCE-FUNCTION RELATIONSHIPS IN ALLOSTERY MEDIATED BY DISORDER-TO-ORDER TRANSITIONS. Christopher Eginton , Dorothy Beckett 1298-P os B oard #B28 HIGH PRECISION FRET REVEALS DYNAMIC STRUCTURES IN THE DROSOPHILA SCAFFOLD PROTEIN COMPLEX STARDUST-DPATJ-DLIN-7 MEDIATED BY L27 DOMAINS. Andreas Renner , Suren Felekyan, Hugo Sanabria, Thomas Peulen, Claus A.M. Seidel, Elisabeth Knust 1299-P os B oard #B29 WIDE EXPLORATION OF OPEP PROTEIN ENERGY LANDSCAPES ORIGIN OF THE ARCHITECTURE OF BIOLOGICAL MACROMOLECULES - A MEAN-FIELD PERSPECTIVE. Jozef A. Liwo , Adam K. Sieradzan, Yi He, Pawel Krupa, Cezary R. Czaplewski, Andrey Krokhotin, Antti J. Niemi, Harold A. Scheraga 1301-P os B oard #B31 PROTEIN FLEXIBILITY AND STABILITY: THERMOPHILES KNOW BEST. Maria Kalimeri , Simone Melchionna, Fabio Sterpone 1302-P os B oard #B32 EXPLORING THE RELATION BETWEEN UNFOLDED PROTEIN ENSEMBLES, TRANSFORMATIONS BETWEEN STRUCTURES, AND REFOLDING KINETICS. Steven Samuel Plotkin 1303-P os B oard #B33 COUPLING BETWEEN PROTEIN CONFORMATION AND LOCAL UNFOLDING HIGHLIGHTS THE ROLE OF DISORDER IN PROTEIN FUNCTION AND SUGGESTS A NEW TARGET FOR COMPUTATIONAL METHODS FOR MEASURING THE FREE ENERGY OF FOLDING IN THE RIBOSOMAL EXIT TUNNEL. Anthony Hazel , James C. Gumbart 1305-P os B oard #B35 STRUCTURE AND DYNAMICS OF INTERMEDIATE PROTEIN STATES BY NMR AND SIMULATIONS. Alfonso De Simone 1306-P os B oard #B36 ELUCIDATING THE STRUCTURAL BASIS OF α -SYNUCLEIN FIBRILLATION USING SMALL CAMELID NANOBODIES. Farah El Turk , Giulia Tomba, Erwin De Genst, Tim Guillams, Predrag Kukic, Michele Vendruscolo, Christopher Dobson USING ADVANCED MONTE CARLO METHODS. Tristan Cragnolini , Kyle H Sutherland-Cash, David Wales, Samuela Pasquali, Philippe Derreumaux 1300-P os B oard #B30 TUBERCULOSIS TREATMENT. Thomas E. Morrell , Ilona U. Rafalska-Metcalf, Jhih-Wei Chu, Haw Yang 1304-P os B oard #B34

1307-P os B oard #B37 INFLUENCE OF GOLD NANOPARTICLES ON THE KINETICS OF ALPHA-SYNUCLEIN AGGREGATION. Yanina D. Alvarez, Jonathan A. Fauerbach , Jessica V. Pellegrotti, Thomas M. Jovin, Elizabeth A. Jares-Erijman, Fernando D. Stefani 1308-P os B oard #B38 UNFOLDING DYNAMICS OF THE CYCLIC NUCLEOTIDE BINDING DOMAIN AND C-LINKER OF HCN CHANNELS. Andrea Pedroni , Anna Moroni, Andrea Alfieri, Loredana Casalis, Paolo Fabris, Vincent Torre 1309-P os B oard #B39 UNFOLDING THE STRUCTURE OF LEUT EMPLOYING LUMINESCENCE RESONANCE ENERGY TRANSFER. Azmat Sohail , Oliver Kudlacek, Markus Daerr, Peggy Stolt-Bergner, Gerhard Ecker, Michael Freissmuth, Klaus Wanner, Thomas Stockner, Walter Sandtner, Harald Sitte 1310-P os B oard #B40 DETERMINING THE RATE OF UNFOLDING AND REFOLDING OF FNIII DOMAINS BY LABELING BURIED CYSTEINE. Riddhi S. Shah , Terrence G. Oas, Harold P. Erickson 1311-P os B oard #B41 LOOKS CAN BE DECEIVING: A SINGLE MUTATION ON AN IG DOMAIN ALTERS DYNAMICS WHILE CONSERVING STRUCTURE. IMPLICATIONS FOR AL, A MISFOLDING DISEASE. Gilberto Valdes-Garcia , Roberto Carlos Maya-Martinez, Cesar Millan-Pacheco, Carlos Amero-Tello, Nina Pastor 1312-P os B oard #B42 SUPER-LONG, SINGLE ALPHA HELICES: A MECHANICAL UNFOLDING STUDY. Matthew Batchelor 1313-P os B oard #B43 INTERACTIONS OF UREA WITH THE FOLDED AND UNFOLDED STATES OF PROTEINS. Yuen Lai Shek , Ikbae Son, Tigran V. Chalikian 1314-P os B oard #B44 VOLUME CHANGES UPON UNFOLDING OF GLOBULAR PROTEINS: COMPUTATIONAL AND EXPERIMENTAL STUDIES. George Makhatadze 1315-P os B oard #B45 CONFORMATIONAL FLEXIBILITY AND STRUCTURE IN HIGH-PRESSURE EXCITED STATES OF APOMYOGLOBIN REVEALED BY SDSL-EPR. Michael Lerch , Carlos López, Wayne L. Hubbell 1316-P os B oard #B46 SINGLE PROTEIN COMPLEXES ISOMERIZATION AND CONFORMATIONAL DYNAMICS USING TRAPPED ION MOBILITY SPECTROMETRY: FROM MS TO SECONDS. Francisco Fernandez-Lima 1317-P os B oard #B47 MINIMA AND BARRIERS ON THE PRESSURE-TEMPERATURE FREE ENERGY LANDSCAPE OF PHOSPHOGLYCERATE KINASE. Maxim B. Prigozhin , Shobhna Kapoor, Roland Winter, Martin Gruebele 1318-P os B oard #B48 ACCELERATED MONTE-CARLO SIMULATIONS FOR ALL-ATOM PROTEIN FOLDING. Moritz Wolf , Timo Strunk, Wolfgang Wenzel

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Biophysical Society 58 th Annual Meeting, San Francisco, California