Significance of Knotted Structures for Function of Proteins and Nucleic Acids - September 17-21, 2014

Significance of Knotted Structures for Function of Proteins and Nucleic Acids

Program

Saturday, September 20, 2014 --------------------------------------------------------------------------------------------------------------------- 8:00 AM – 5:00 PM Registration/Information Auditorium Lobby Session: DNA Topology and Topoisomerase Chair: Lynn Zechiedrich, Baylor College of Medicine, USA 8:30 – 9:00 AM Tony Maxwell, John Innes Center, Norwich Research Park, United Kingdom DNA Topology, DNA Topoisomerases, and Small DNA Circles 9:00 – 9:30 AM Stephen Levene, University of Texas, Dallas, USA Conformational Free-Energy Calculations for Complex Biopolymer Structures

9:30 – 10:00 AM

Phoebe Rice, University of Chicago, USA Structural Basis for Regulation of Site-specific DNA Recombinases by DNA Topology

10:00 – 10:30 AM

Anjum Ansari, University of Illinois at Chicago, USA Unveiling the Molecular Trajectory during Binding Site Recognition by DNA-bending Proteins

Auditorium Lobby

10:30 – 10:45 AM

Coffee Break

Session: DNA/RNA, Nanorobots, Origami – Theory/Experiment, Part 1 Chair: Remus Dame, Leiden Institute of Chemistry, The Netherlands

10:45 – 11:15 AM

Giovanni Dietler, Swiss Federal Institute of Technology (EPFL), Switzerland Sedimentation of Macroscopic Rigid Knots and its Relation to Gel Electrophoretic Mobility of DNA Knots Julie Feigon, University of California, Los Angeles, USA RNA Pseudoknots in Telomerase and Riboswitches Ebbe Andersen, Aarhus University, Denmark Single-stranded Architecture for Cotranscriptional Folding of RNA Nanostructures Zbyszek Otwinowski, UT Southwestern Medical Center, USA* Single-stranded DNA Topology in Eukaryotes

11:15 – 11:45 AM

11:45 AM – 12:15 PM

12:15 – 12:30 PM

12:30 – 3:30 PM

Lunch and Free Time

*Short talks selected from among submitted abstracts

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