Significance of Knotted Structures for Function of Proteins and Nucleic Acids - September 17-21, 2014

Significance of Knotted Structures for Function of Proteins and Nucleic Acids

Program

Session: DNA/RNA, Nanorobots, Origami – Theory/Experiment, Part 2 Chair: Giovanni Dietler, Swiss Federal Institute of Technology (EFPL), Switzerland Lynn Zechiedrich, Baylor College of Medicine, USA How Positive or Negative Supercoiling Affects the Structure of Reactivity of DNA Pawel Zawadzki, Oxford University, United Kingdom* Escherichia coli Live Cell Super-resolution Analysis of Topoisomerase IV Action Remus Dame, Leiden Institute of Chemistry, The Netherlands Fine-tuning the Activity of DNA Bridging Proteins Sarah Harris, University of Leeds, United Kingdom Closing the Loop: Comparing the Results of Experiment and Computer Simulations in the Study of DNA Minicircles Session: Energy Landscape Proteins Chair: Joanna Sulkowska, University of Warsaw, Poland Jose Onuchic, Rice University, USA Knotting a Protein in the Computer – From Simple Models to Explicit Solvent Simulations Coffee Break

3:30 – 4:00 PM

4:00 – 4:15 PM

4:15 – 4:45 PM

Auditorium Lobby

4:45 – 5:00 PM

5:00 – 5:30 PM

5:30 – 6:00 PM

Sunday, September 21, 2014 --------------------------------------------------------------------------------------------------------------------- 8:00 AM – 12:00 PM Registration/Information Auditorium Lobby Session: DNA Knots and Viral Topology, Part I Chair: Alexander Grosberg, New York University, USA 8:30 – 9:00 AM Todd Yeates, University of California, Los Angeles, USA Discoveries, Implications and Utilities of Proteins with Barriers, Knots, Slipknots, and Links 9:00 – 9:30 AM Marek Cieplak, Polish Academy of Sciences, Poland Knotted Proteins under Tension 9:30 – 10:00 AM Peter Virnau, Johannes Gutenberg University, Germany Molecular Simulations of Knotted Proteins and DNA

10:00 – 10:30 AM

Tetsuo Deguchi, Ochanomizu University, Japan Probability of DNA Knots and the Effective Diameter of DNA Double Helix

*Short talks selected from among submitted abstracts

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