BPS Program Book 2014

2469-P os B oard #B161 SEQUENCE-SPECIFIC RNAP-DNA INTERACTIONS IN TRANSCRIPTION INITIATION AND ELONGATION: CORE RECOGNITION ELEMENT (CRE). Hanif Vahedian-Movahed , Yu Zhang, Richard H. Ebright 2470-P os B oard #B162 TOWARD A GENERAL MECHANISM FOR TRANSCRIPTION INITIATION. Emily Ruff , Dmitri Svetlov, Noah Bown, Trenton Persing, Stephanie Chong-Macias, Amanda Drennan, Irina Artsimovitch, M. Thomas Record, Jr. 2471-P os B oard #B163 PROMOTER ARCHITECTURE DICTATES VARIABILITY IN GENE EXPRESSION. Daniel L. Jones , Robert Brewster, Rob Phillips 2472-P os B oard #B164 education travel awardee SINGLE MOLECULE INVESTIGATION OF RNA POLYMERASE I USING MULTIPLEXED TETHERED PARTICLE MOTION. Suleyman Ucuncuoglu , David A. Schneider, David D. Dunlap, Laura Finzi 2473-P os B oard #B165 THE TRANSCRIPTION FACTOR TITRATION EFFECT DICTATES LEVEL OF GENE EXPRESSION. Franz M. Weinert , Robert C. Brewster, Hernan G. Garcia, Linda Song, Mattias Rydenfelt, Rob Phillips 2474-P os B oard #B166 INHIBITION OF TUMOR CELL GROWTH THROUGH THE ENVIRONMENTAL EPIGENETIC REGULATION AT 2ATA ELEVATED PRESSURE (EP) IN H460 LUNG CANCER CELLS. EunJeong Cha , Eunil Lee, Gwang Ic Son  Ribosome and Translation (Boards #B167–#B188) 2475-P os B oard #B167 CRITICAL DECODING STEP IN THE RIBOSOME REVEALED BY DYNAMICAL NETWORK ANALYSIS. Rezvan Shahoei , Klaus Schulten 2476-P os B oard #B168 EXCLUDED VOLUME OF EF-TU GREATLY REDUCES THE BARRIER TO ACCOMMODATION FOR AA-TRNA IN THE RIBOSOME. Jeffrey K. Noel , Paul Whitford 2477-P os B oard #B169 TRANSLATION IN THE RNA WORLD: INSIGHT FROM THE PROTO-RIBOSOME MODEL. Ke Chen , Bo Wang, Jingyi Fei, Zaida Luthey-Schulten 2478-P os B oard #B170 EF-G:A-SITE TRNA DISTANCE CHANGES DURING TRANSLOCATION. Rong Shen , Chunlai Chen, Yale E. Goldman, Barry S. Cooperman 2479-P os B oard #B171 THE RIBOSOMAL PRE STATE IN STALLED VS. ACTIVELY TRANSLATING RIBOSOMES. Ryan M. Jamiolkowski , Chunlai Chen, Barry S. Cooperman, Yale E. Goldman 2480-P os B oard #B172 AN MRNA DOWNSTREAM STRUCTURE PROMOTES FRAMESHIFTING BY DESTABILIZING THE HYBRID STATE AND IMPEDING THE EF-G DRIVEN TRANSLOCATION PROCESS. Hee-Kyung Kim , Fei Liu, Jingyi Fei, Ruben L. Gonzalez Jr, Carlos Bustamante, Ignacio Tinoco Jr

2458-P os B oard #B150 DIRECT ASSESSMENT OF TRANSCRIPTION FIDELITY BY RNA

SEQUENCING. Masahiko Imashimizu , Taku Oshima, Hiroki Takahashi, Lucyna Lubkowska, Mikhail Kashlev 2459-P os B oard #B151

TFIIF AND TFIIS ENHANCE THE MECHANICAL PERSISTENCE OF TRANSCRIPT ELONGATION BY RNA POLYMERASE II. Volker Schweikhard , Cong A. Meng, Kenji Murakami, Craig D. Kaplan, Roger D. Kornberg, Steven M. Block 2460-P os B oard #B152 CARD REGULATION OF MYCOBACTERIAL TRANSCRIPTION INITIATION. Jayan Rammohan , Ashley Garner, Ana Ruiz-Manzano, Christina Stallings, Eric Galburt 2461-P os B oard #B153 PHOTOPHYSICAL PROPERTIES OF THE SPINACH-DFHBI RNA APTAMER-FLUOROGEN COMPLEX AND ITS APPLICATIONS TO LIVE CELL IMAGING WITH IMPROVED FLUORESCENCE SIGNAL. Kyu Young Han , Benjamin J. Leslie, Jingyi Fei, Jichuan Zhang, CHANNELS IN E. COLI. Stephanie Barnes , Daniel Jones, Nathan Belliveau, Sushant Sundaresh, Justin Kinney, Rob Phillips 2463-P os B oard #B155 COOPERATIVITY AND INTERACTION ENERGY THRESHOLD EFFECTS IN RECOGNITION OF THE -10 PROMOTER ELEMENT BY BACTERIAL RNA POLYMERASE. Vladimir Mekler , Konstantin Severinov 2464-P os B oard #B156 cpow travel awardee SUPER-RESOLUTION FLUORESCENCE MICROSCOPY OF TRANSCRIPTION SITES IN E. COLI. Ulrike Endesfelder , Kieran Finan, Seamus Holden, Peter R. Cook, Achillefs N. Kapanidis, Mike Heilemann 2465-P os B oard #B157 CHARACTERIZATION OF TRANSCRIPTION INITIATION INTERMEDIATES IN ESCHERICHIA COLI RNA POLYMERASE BY FLUORESCENCE. Raashi Sreenivasan , Sara Heitkamp, Michael Capp, Irina Artsimovitch, Thomas Record 2466-P os B oard #B158 ACTIVATING THE PROKARYOTIC LEU-500 PROMOTER BY TRANSIENT, DYNAMIC DNA SUPERCOILING IN ESCHERICHIA COLI. Xiaoduo Zhi, Catherine Perez, Samantha Dages, Kelley Dages, Steve Eichelbaum, John Makemson, Fenfei Leng 2467-P os B oard #B159 NUCLEOTIDE STRUCTURAL POLYMORPHISMS FORMED BY GGGGCC REPEATS CAUSE C9ORF72 ABORTIVE TRANSCRIPTION AND NUCLEOLAR STRESS. Aaron R. Haeusler 2468-P os B oard #B160 MECHANICAL STRAIN GENERATED BY RNA POLYMERASE DURING TRANSCRIPTION INITIATION CAN DRIVE STRUCTURAL CHANGES IN DNA TOPOLOGY THAT RELIEVE REPRESSION. Troy A. Lionberger , Ankit Vahia, Andrew D. Hirsh, Maryna Taranova, Ioan Andricioaei, Noel C. Perkins, Edgar Meyhöfer, Craig T. Martin Taekjip Ha 2462-P os B oard #B154 IDENTIFICATION AND ANALYSIS OF THE TRANSCRIPTIONAL REGULATORY NETWORKS GOVERNING MECHANOSENSITIVE

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Biophysical Society 58 th Annual Meeting, San Francisco, California