BPS Program Book 2014

2863-P os B oard #B555 CLINICAL TRIALS OF GENE THERAPY FOR HEART FAILURE: QUANTITATION OF THE CARDIAC CALCIUM PUMP BY IMMUNOCHEMISTRY. Holly R. Langer , Joseph M. Autry, Brock Carlson, Margaret Gadek, David D. Thomas 2864-P os B oard #B556 SARCOPLASMIC RETICULUM-INDEPENDENT CONTRACTILE FUNCTION IN SERCA2 ABLATED HEARTS. Frazer I. Heinis , Joseph M. Metzger 2865-P os B oard #B557 SIMULTANEOUS IMAGING OF LOCAL CALCIUM AND SINGLE SARCOMERE LENGTH IN RAT NEONATAL CARDIOMYOCYTES VIA EXPRESSION OF CAMELEON-NANO IN Z-DISCS. Seiichi Tsukamoto , Kotaro Oyama, Seine A. Shintani, Norio Fukuda, Shin’ichi Ishiwata 2866-P os B oard #B558 REAL-TIME INTRACELLULAR CALCIUM IMAGING IN THE HEART. Erisa Hirokawa , Kotaro Oyama, Takako Terui, Togo Shimo- zawa, Shin’ichi Ishiwata, Norio Fukuda  Actin and Actin-binding Proteins II (Boards #B559–#B575) 2867-P os B oard #B559 STRUCTURAL ANALYSIS OF INTRINSICALLY DISORDERED PROTEIN (IDP): TRIOBP. Laura K. Gunther, Jianjun Bao, Kavitha Thirumurugan, Shin-ichiro Kitajiri, Takeshi Sakamoto 2868-P os B oard #B560 MYOSIN II DOES IT ALL: ASSEMBLY, REMODELING, AND DISASSEMBLY OF ACTIN NETWORKS ARE GOVERNED BY MYOSIN II ACTIVITY. Yaron Ideses , Anne Bernheim, Adar Sonn, Yael Roichman 2869-P os B oard #B561 REGULATION OF ACTIN DYNAMICS BY TROPOMYOSIN. Sofia Yu. Khaitlina , Horst Hinssen 2870-P os B oard #B562 REGULATION OF NONMUSCLE MYOSIN II BY TROPOMYOSIN ISOFORMS. Bipasha Barua , Attila Nagy, James R. Sellers, Sarah E. Hitchcock-DeGregori 2871-P os B oard #B563 GEOMETRICAL AND MECHANICAL PROPERTIES CONTROL ACTIN FILAMENT ORGANIZATION. Gaelle Letort , Antonio Politi, Hajer Ennomani, Manuel Thery, Francois Nedelec, Laurent Blanchoin 2872-P os B oard #B564 THE ROLE OF CALDESMON AND ITS PHOSPHORYLATION BY ERK ON THE BINDING FORCE OF UNPHOSPHORYLATED MYOSIN TO ACTIN. Horia N. Roman , Nedjma B. Zitouni, Linda Kachmar, Apolinary Sobieszek, Anne-Marie Lauzon 2873-P os B oard #B565 ACTOMYOSIN REGULATION BY TM5NM1, A NON-MUSCLE ISOFORM OF TROPOMYOSIN. Bipasha Barua , Gioia Kennedy, Parry Mendapara, Ravi Shah 2874-P os B oard #B566 COFILIN BINDING TO GLOBULAR AND FILAMENTOUS ACTIN. Joo-Mee Hwang, Yaxin Lu, Murat Kekic, Deepak Chhabra, Peter Fajer, Brett D. Hambly

2852-P os B oard #B544 PHYSIOLOGICAL CONTRACTILITY OF CARDIOMYOCYTES IN THE WALL OF MOUSE AND RAT AZYGOS VEIN. Rong Liu , Han-Zhong Feng, J.-P. Jin 2853-P os B oard #B545 ZEBRAFISH HEART AS A MODEL SYSTEM TO STUDY STRUCTURE-FUNCTION RELATIONSHIPS. Alexey V. Dvornikov , Sukriti Dewan, Olga V. Alekhina, F Bryan Pickett, Pieter P. de Tombe 2854-P os B oard #B546 MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF UNIFORM-SIZED BEATING EMBRYOID BODIES AND CARDIOMYOCYTES FROM HUMAN EMBRYONIC AND INDUCED PLURIPOTENT STEMCELLS. Martin Pesl, Acimovic Ivana, Jan Pribyl, Renata Hezova, Aleksandra Vilotic, Franck Aimond, Jeremy Fauconnier, Jan Vrbsky, Peter Kruzliak, Peter Skladal, Tomas Kara, Vladimir Rotrekl, Alain Lacampagne, Petr Dvorak, Albano C. Meli 2855-P os B oard #B547 ASSESSING THE CONTRACTILITY OF HUMAN IPS DERIVED CARDIOMYOCYTES WITH ARRAYS OF MICROPOSTS. Marita L. Rodriguez , Brandon T. Graham, Lil M. Pabon, Sangyoon J. Han, Charles E. Murry, Nathan J. Sniadecki 2856-P os B oard #B548 MECHANICAL ANALYSIS OF SINGLE MYOCYTE CONTRACTION IN A 3D ELASTIC MATRIX. John Shaw , Leighton Izu, Ye Chen-Izu 2857-P os B oard #B549 LOCALIZED NITRIC OXIDE SIGNALING MEDIATES CARDIAC MECHANO-CHEMOTRANSDUCTION. Zhong Jian, Huilan Han, Tieqiao Zhang, Jose Puglisi, Leighton T. Izu, John Shaw, Yi-Je Chen, Rafael Shimkunas, Nipavan Chiamvimonvat, Donald M. Bers, Kit S. Lam, Ye Chen-Izu 2858-P os B oard #B550 CARDIOMYOPATHY CTNT MUTATION IN PATIENT DERIVED CARDIOMYOCYTES FROM INDUCED PLURIPOTENT STEM CELLS AFFECTS SARCOMERE STRUCTURE AND FUNCTION. Kathleen M. Broughton , Veronica Sanchez-Freire, Joseph C. Wu, Beata M. Wolska, Ross J. Solaro, Brenda Russell 2859-P os B oard #B551 CONTRACTILE STRUCTURE-FUNCTION OF PARVALBUMIN’S EF-HAND METAL ION BINDING LOOP IN ISOLATED ADULT CARDIAC MYOCYTES. Michelle L. Asp , Joseph M. Metzger 2860-P os B oard #B552 PHOSPHOLAMBAN AND SARCOLIPIN PENTAMERS NATURALLY ASSOCIATE WITH THE SARCOPLASMIC RETICULUM CALCIUM PUMP. John Paul Glaves, Przemek Gorski, Joseph Primeau, Catharine Trieber, Howard S. Young 2861-P os B oard #B553 PHOSPHOLAMBAN C-TERMINAL TRUNCATIONS INCLUDING HEART FAILURE MUTATION L39STOP DECREASE MEMBRANE LOCALIZATION AND OLIGOMERIZATION AND ALTER THE STRUCTURE OF THE PLB-SERCA COMPLEX. Neha Abrol , Nikolai Smolin, Delaine K. Ceholski, Howard S. Young, Seth L. Robia 2862-P os B oard #B554 FLUORESCENCE RESONANCE ENERGY TRANSFER REVEALS THAT SERCA DIMERIZES AND FORMS A COMPLEX WITH PHOSPHOLAMBAN IN A 2:1 STOICHIOMETRY. Daniel Blackwell , Seth L. Robia

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Biophysical Society 58 th Annual Meeting, San Francisco, California