BPS Program Book 2014

10:45 am –12:45 pm , R oom 134 Symposium RNA Assemblies and DNA Origami

137-P lat 11:00 am NANOSCOPY BY FLUORESCENCE DEMODULATION AND POLARIZATION ANGLE NARROWING. Peter J. Walla , Nour Hafi, Matthias Grunwald, Laura Van den Heuvel, Aspelmeier Timo, Marta Zagrebelsky, Martin Korte, Axel Munk 138-P lat 11:15 am CIRCADIAN METABOLIC OSCILLATIONS IN THE EPIDERMIS STEM CELLS BY FLUORESCENCE LIFETIME MICROSCOPY OF NADH IN VIVO. Chiara Stringari , Mikhail Geyfman, Hong Wang, Viera Crosignani, Vivek Kumar, Joseph S. Takahashi, Bogi Andersen, Enrico Gratton 139-P lat 11:30 am IMAGING OF INTRACELLULAR VISCOSITY AND MEMBRANE ORDER BY NEW MOLECULAR ROTORS SUITABLE FOR PHASOR ANALYSIS OF FLUORESCENCE LIFETIME. Giovanni Signore, Gerardo Abbandonato, Antonella Battisti, Silvio Panettieri, Barbara Storti, Emanuela Jacchetti, Francesco Cardarelli, Fabio Beltram, Ranieri Bizzarri 140-P lat 11:45 am TIME SUPER-RESOLUTION FLUORESCENCE IMAGING BY EVENT CORRELATION MICROSCOPY. Manfred Lindau , Qinghua Fang, Ying Zhao 141-P lat 12:00 pm HIGH RESOLUTION SURFACE PLASMON RESONANCE IMAGING OF FOCAL ADHESIONS IN SINGLE CELLS. Alexander W. Peterson , Michael Halter, Alessandro Tona, Kiran Bhadriraju, John T. Elliott, Anne L. Plant 142-P lat 12:15 pm CORRELATION FUNCTIONS PROVIDE A UNIVERSAL FRAMEWORK FOR QUANTITATIVE ANALYSIS OF LOCALIZATION-BASED SUPER-RESOLUTION MICROSCOPY IMAGES. Joerg Schnitzbauer , Xiaoyu Shi, Robert Kasper, Baohui Chen, Shijie Zhao, Daichi Kamiyama, Bo Huang 143-P lat 12:30 pm SUPER-RESOLUTION IMAGING OF PROTEIN-PROTEIN IN- TERACTIONS BY BIMOLECULAR COMPLEMENTATION OF PHOTOACTIVATABLE FLUORESCENT PROTEINS. Antony Lee , Alyssa B. Rosenbloom, Sang-Hyuk Lee, Carlos Bustamante 10:45 am –12:45 pm , R oom 132/133 Platform Protein Gymnastics of Large-Scale Structural Rearrangements Co-Chairs Andy LiWang, University of California, Merced Michael Nilges, Pasteur Institute, France 144-P lat 10:45 am ROBUSTNESS OF ROTARY CATALYSIS MECHANISM OF F 1 -ATPASE. Rikiya Watanabe , Hiroyuki Noji 145-P lat 11:00 am ELECTROSTATIC BASIS OF THE UNIDIRECTIONAL WALKING MOTION IN MYOSIN MOLECULAR MOTORS. Shayantani Mukherjee , Arieh Warshel 146-P lat 11:15 am DIFFERENT 3D DOMAIN-SWAPPED OLIGOMERIC CYANOVIRIN-N STRUCTURES SUGGEST TRAPPED FOLDING INTERMEDIATES. Leonardus Koharudin , Lin Liu, Angela M. Gronenborn

F R I D A Y

S A T U R D A Y U N D A Y

Co-Chairs Christina Smolke, Stanford University Andrew Turberfield, University of Oxford, United Kingdom 132-S ymp 10:45 am

DESIGNING SYNTHETIC REGULATORY RNAS: NEW TOOLS FOR TEMPORAL AND SPATIAL CONTROL IN BIOLOGICAL SYSTEMS. Christina Smolke 133-S ymp 11:15 am MOLECULAR MACHINERY FROM DNA: SYNTHETIC BIOLOGY FROM THE BOTTOM UP. Andrew J. Turberfield 134-S ymp 11:45 am STRUCTURAL EVOLUTION OF RNA SELF-ASSEMBLY. Luc Jaeger 135-S ymp 12:15 pm DYNAMIC DNA ORIGAMI-BASED NANOPARTICLE ASSEM- BLIES. Tim Liedl 10:45 am –12:45 pm , R oom 135 Symposium New and Notable Chair Robert Nakamoto, University of Virginia Health Science Center N o A bstract 10:45 am Structure of the CRISPR RNA-guided Surveillance Complex from the Adaptive Immune System in Escherichia coli. Blake Wiedenhef N o A bstract 11:02 am Elucidation of Filamentous Structures in Immune Signaling. Hao Wu N o A bstract 11:19 am High throughput 3D PALM Imaging Elucidates Mechanisms of Bacterial Cell Division. Suliana Manley N o A bstract 11:36 pm ChromosomeTerritories Spatially Reorganise during DNA-Damage Response inMammalian Nuclei. Basuthkar Rao N o A bstract 11:53 pm Myosin II Functions as a Direct Mechanosensor for Intercellular Invasion during Cell-Cell Fusion. 12:10 pm Sterol Binding Controls Partitioning of the Amyloid Precursor C99 Protein between Ordered and Disordered Membranes. Anne Kenworthy N o A bstract 12:27 pm Structural Insights intoTRP Channel Activation. Erhu Cao 10:45 am –12:45 pm , R oom 130/131 Platform Optical Microscopy and Super Resolution Imaging I Co-Chairs Don Lamb, LMU Munich, Germany Manfred Lindau, Cornell University 136-P lat 10:45 am 3D REAL-TIME ORBITAL TRACKING MICROSCOPY IN ZEBRA FISH EMBRYOS. Fabian Wehnekamp, Gabriela Gabriela, Christoph Bräuchle, Thomas Misgeld, Don C. Lamb Elizabeth Chen N o A bstract

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Biophysical Society 58 th Annual Meeting, San Francisco, California