BPS Program Book 2014

3285-P os B oard #B13 SUPERVISED LEARNING ON MARKOV STATES AS A METHOD FOR GAINING INSIGHT INTO PROTEIN ALLOSTERY. Mohammad M. Sultan 3286-P os B oard #B14 ALLOSTERIC MODULATION OF CADHERIN AFFINITY. Nitesh Shashikanth , Jillian Newhall, Yuliya Petrova, Barry M. Gumbiner, Deborah Leckband 3287-P os B oard #B15 SECTOR ANALYSIS OF PROTEIN BASED ON MOLECULAR DYNAMICS SIMULATIONS: ROLE OF ATOMIC FLUCTUATIONS IN SINGLE DOMAIN ALLOSTERISM. Lakhani Bharat , Beveridge L. David 3288-P os B oard #B16 education travel awardee DYNAMIC BEHAVIOR OF OLIGOMERIC INORGANIC PYROPHOSPHATASE (IPPASE) STUDIED BY QUASIELASTIC NEUTRON SCATTERING. Utsab R. Shrestha , Kurt VanDelinder, Manavalan Gajapathy, John Copley, Juscelino Leao, Joseph D. Ng, Xiang-Qiang Chu 3289-P os B oard #B17 ALLOSTERIC REGULATION OF PROTEIN KINASE ENZYMES VIA AN ELECTROSTATIC SWITCH THAT MODULATES ACTIVE SITE DYNAMICS. Matthew A. Young , Douglas M. Jacobsen, Zhao-Qin Bao 3290-P os B oard #B18 A NETWORK OF “MOLECULAR-SWITCHES” CONTROL THE ACTIVATION OF KEY BACTERIAL SIGNALING PROTEIN. Dan Vanatta 3291-P os B oard #B19 COARSE-GRAINED MODELING OF THE DYNAMICS AND ALLOSTERIC MODULATION OF HRAS PROTEIN. Abhijeet Kapoor , Alex Travesset 3292-P os B oard #B20 REDISTRIBUTION OF FLEXIBILITY IN STABILIZING ANTIBODY FRAGMENT MUTANTS FOLLOWS LE CHATELIER’S PRINCIPLE. Tong Li, Malgorzata B. Tracka, Shahid Uddin, Jose Casas-Finet, Donald J. Jacobs , Dennis R. Livesay 3293-P os B oard #B21 education travel awardee GENERALIZED MODEL-FREE SPECTRAL DENSITY ANALYSIS APPLIED TO RHODOPSIN ACTIVATION IN MEMBRANES. Xiaolin Xu , Andrey V. Struts, K. J. Mallikarjunaiah, Michael F. Brown 3294-P os B oard #B22 CONFORMATIONAL MOTION IN GENE REGULATORY PROTEINS. David V. Svintradze 3295-P os B oard #B23 DIFFERENCES IN TROPONIN C DYNAMICS BETWEEN CARDIAC AND SKELETAL MUSCLE - A MOLECULAR DYNAMICS PERSPECTIVE. Steffen Lindert , Andy McCammon 3296-P os B oard #B24 THE ROLE OF CONFORMATIONAL FLEXIBILITY IN INHIBITOR BINDING AND SUBSTRATE RECOGNITION FOR CYP119. Xiaoxiao Shi , Shu-Hao Liou, R.David Britt, David B. Goodin 3297-P os B oard #B25 CONFORMATIONAL CHANGES IN PROTEIN BINDING PROCESSES. Béla Voß , Helmut Grubmüller

Correlated Motions in Proteins (Boards #B1–#B30)

3273-P os B oard #B1 DISTINCT DYNAMIC SIGNATURES OF AMYLOIDOGENIC INSULIN REVEALED BY NEUTRON SPIN ECHO SPECTROSCOPY. Claus Czeslik , Mirko Erlkamp, Roland Winter 3274-P os B oard #B2 GSATOOLS: ANALYSIS OF ALLOSTERIC COMMUNICATION AND FUNCTIONAL LOCAL MOTIONS USING A STRUCTURAL ALPHABET. Alessandro Pandini , Arianna Fornili, Franca Fraternali, Jens Kleinjung 3275-P os B oard #B3 RECAPTURING THE CORRELATED MOTIONS OF PROTEIN BY USING COARSE GRAINED MODELS. Yan Lu , Freddie R. Salsbury, Jr 3276-P os B oard #B4 MODULATION OF ACTIVE SITE PICOSECOND DYNAMICS IN MUTANT FORMS OF A THERMOPHILIC ALCOHOL DEHYDROGENASE (HT-ADH). Corey W. Meadows , Judith P. Klinman 3277-P os B oard #B5 ATP BINDING INDUCED CONFORMATIONAL CHANGE IN RECQ HELICASE. Maria Mills , Keir Neuman 3278-P os B oard #B6 THERMODYNAMIC BASIS OF THE ALLOSTERIC ACTIVATION OF PROTEIN KINASE A. Jonggul Kim , Frank Chao, Gianluigi Veglia 3279-P os B oard #B7 PROBING ALLOSTERIC MECHANISMS OF UTROPHIN AND DYSTROPHIN ACTIN-BINDING DOMAINS, USING THERMAL DENATURATION. Michael E. Fealey , Jonathan Crain, Anne Hinderliter, David D. Thomas 3280-P os B oard #B8 TEMPERATURE DEPENDENCE OF THE PROTEIN- CHROMOPHORE HYDROGEN BOND DYNAMICS IN THE FAR-RED FLUORESCENT PROTEIN MPLUM. Chola K. Regmi , Prem P. Chapagain, Bernard S. Gerstman 3281-P os B oard #B9 DYNAMICS OF NEUROTOXIN II PROVIDES ADAPTIVITY OF ITS FUNCTIONAL SITES. Dmitry M. Lesovoy , Svetlana B. Nolde, Eduard V. Bocharov, Ekaterina N. Lyukmanova, Dmitry A. Dolgikh, Mikhail P. Kirpichnikov, Alexander S. Arseniev 3282-P os B oard #B10 education travel awardee THE DYNAMIC FUNCTIONAL CONSEQUENCES OF THE THROMBIN-THROMBOMODULIN INTERACTION. Lindsey D. Handley , Kyle N. Stearns, Elizabeth A. Komives 3283-P os B oard #B11 COMPUTATIONAL SIMULATIONS REVEAL HOW CALMODULIN METHIONINE OXIDATION TRIGGERS LARGE-SCALE CHANGES IN STRUCTURAL DYNAMICS. Michael Olenek , David D. Thomas, Jennifer C. Klein 3284-P os B oard #B12 ALLOSTERIC EFFECTORS HAVE AN ASYMMETRIC EFFECT ON THE COMPRESSIBILITY OF HEMOGLOBIN SUBUNITS. Gusztav Schay , Andras Kaposi, Miklos Kellermayer, Laszlo Smeller, Levente Herenyi, Krisztian Szigeti, Judit Fidy

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Biophysical Society 58 th Annual Meeting, San Francisco, California