BPS Program Book 2014

3450-P os B oard #B178 THE OLIGOMERIC STATE OF HUMAN ALPHA-DEFENSIN 1 IN SOLUTION. Grzegorz Piszczek 3451-P os B oard #B179 AGGREGATION OF TRANSFORMING GROWTH FACTOR BETA INDUCED PROTEIN STUDIED BY PROTEIN-PROTEIN DOCKING. Ole J. Andersen , Heidi Koldsø, Birgit Schiøtt 3452-P os B oard #B180 STABLE AMYLOID OLIGOMERS CAN SEED FIBRIL GROWTH NEAR PHYSIOLOGICAL CONDITIONS. Mentor Mulaj , Tatiana Miti, Joseph Foley, Martin Muschol 3453-P os B oard #B181 PHASE BOUNDARIES FOR FIBRIL AND METASTABLE OLIGOMER FORMATION OF LYSOZYME. Tatiana Miti , Mentor Mulaj, Joseph Foley, Martin Muschol 3454-P os B oard #B182 POLYGLUTAMINE FLANKING REGIONS IN HUNTINGTIN HIGHLIGHT KEY STRUCTURAL INTERMEDIATES RELEVANT FOR MOLECULAR CHAPERONE INTERACTION AND HUNTINGTON’S DISEASE PATHOGENESIS. Koning Shen , Barbara Calamini, Donald Lo, Judith Frydman 3455-P os B oard #B183 KINETICS OF THE INTERCONVERSION BETWEEN TWO PHYSIOLOGICALLY IMPORTANT COPPER-BOUND AMYLOID-BETA SPECIES. Thomas Branch , Mauricio Barahona, Liming Ying 3456-P os B oard #B184 INSIGHTS INTO THE INHIBITION MECHANISM OF BIOMOLECULAR SELF-ASSEMBLY FROM CHEMICAL FILAMENT ASSEMBLY BY PHOSPHOFRUCTOKINASE-1, THE GATEKEEPER OF GLYCOLYSIS. Bradley Webb , Larry Ackerman, Diane Barber 3458-P os B oard #B186 AMYLOID β -PROTEIN: THE INFLUENCE OF INTRINSIC AND EXTRINSIC FACTORS ON FIBRIL FORMATION. Risto Cukalevski , Xiaoting Yang, Samuel Cohen, Barry Boland, Birgitta Frohm, Eva Thulin, Dominic Walsh, Tuomas Knowles, Sara Linse 3459-P os B oard #B187 HIV-TAT PROTEIN ENHANCES AMYLOID BETA PEPTIDE AGGREGATION. Alina Popescu Hategan , Joseph Steiner, Emilios K. Dimitriadis, Avindra Nath 3460-P os B oard #B188 THE AGGREGATION-PRONE MUTANT HUNTINGTIN PROTEIN IN A CELLULAR CONTEXT - APPROACHES BY SUPER-RESOLUTION IMAGING. Steffen J. Sahl , Willianne I M Vonk, Lucien E. Weiss, Lana Lau, Judith Frydman, W. E. Moerner 3461-P os B oard #B189 cpow travel awardee NANOSCALE ASSEMBLY OF PROTEINS INTO AMYLOID OLIGOMERS, PORES AND FIBRILS. Mily Bhattacharya , Neha Jain, Priyanka Dogra, Vijit Dalal, Dominic Narang, Pushpender K. Sharma, Soumyadyuti Samai, Samrat Mukhopadhyay KINETICS. Paolo Arosio , Michele Vendruscolo, Christopher M. Dobson, Tuomas P.J. Knowles 3457-P os B oard #B185

3462-P os B oard #B190 international travel awardee ATOMISTIC SIMULATIONS LEND MECHANISTIC INSIGHTS INTO PLAUSIBLE WAYS OF PERTURBING THE NUCLEATION THERMODYNAMICS OF THE FULL-LENGTH A β PEPTIDE. Asis K. Jana, Neelanjana Sengupta 3463-P os B oard #B191 THE FORMATION OF HIGHER ORDER STRUCTURES BY THE NEURONAL PROTEIN ALPHA-SYNUCLEIN: SELF-ASSEMBLY OVER MULTIPLE LENGTH SCALES. Slav Semerdzhiev , Mireille Claessens, Vinod Subramaniam 3464-P os B oard #B192 STRUCTURAL BASIS FOR THE PRION-LIKE MAVS FILAMENTS IN ANTIVIRAL INNATE IMMUNITY. Hui Xu , Xiaojing He, Hui Zheng, Lily Huang, Fajian Hou, Zhiheng Yu, Michael J. de la Cruz, Brian Borkowski, Xuewu Zhang, Zhijian J. Chen, Qiu-xing Jiang 3465-P os B oard #B193 AMYLOIDS: CONNECTING FROM SINGLE FIBRIL MECHANICS TO MACROSCOPIC RHEOLOGY. Corianne C. van den Akker , Jeanette Nguyen, Michael Schleeger, Krassimir P. Velikov, Mischa Bonn, Gijsje H. Koenderink 3466-P os B oard #B194 RECOGNITION OF AMYLOIDOGENIC SEGMENTS BASED ON SITE SPECIFIC AMINOACID PAIRWISE CORRELATIONS. Pawel Gasior, Malgorzata Kotulska 3467-P os B oard #B195 ELONGATION OF MURINE PRION PROTEIN AMYLOID-LIKE FIBRILS: EFFECT OF TEMPERATURE AND DENATURANT CONCENTRATION. Katazyna Milto, Ksenija Michailova, Vytautas Smirnovas 3468-P os B oard #B196 PYROGLUTAMYLATED AMYLOID-BETA PEPTIDE REVERSES CROSS BETA-SHEETS BY A PRION-LIKE MECHANISM. Jason O. Matos, Greg Goldblatt, Suren A. Tatulian 3469-P os B oard #B197 COLLAGEN SINGLE FIBRIL ELASTIC MODULUS MEASUREMENT TECHNIQUE. Pavel Dutov , Jay D. Schieber, Olga Antipova, Sameer Varma, Joseph Orgel 3470-P os B oard #B198 EVOLUTIONARY EXCURSIONS IN QUATERNARY STRUCTURE SPACE. Joseph A. Marsh , Sebastian E. Ahnert, Sarah A. Teichmann 3471-P os B oard #B199 DEFINING PROTEIN COMPLEXES THAT MEDIATE BACTERIAL CHEMOTAXIS BY PULSED DIPOLAR ESR SPECTROSCOPY. Brian R. Crane, Peter P. Borbat, Jack H. Freed 3472-P os B oard #B200 INTERACTION OF BETA-SHEETS TO FORM AGGREGATES AND FIBRILS. THEORETICAL AND EXPERIMENTAL SPECTROSCOPIC STUDIES OF PEPTIDE IR AND VCD SPECTRA. Heng Chi, William R. W. Welch, Jan Kubelka, Jiri Kessler, Petr Bour, Timothy A. Keiderling 3473-P os B oard #B201 DESTABILIZING AMYLOID FIBRILS BY SELECTIVE SEQUENCE MUTATIONS ENABLED BY COMPUTATIONAL ASSEMBLY OF POLYMORPHIC STRUCTURES. Mohamed R. Smaoui , Jerome Waldispuhl

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Biophysical Society 58 th Annual Meeting, San Francisco, California