BPS Program Book 2014

543-P os B oard #B298 MONITORING CONFORMATIONAL CHANGES DURING AGONIST RELEASE FROM A GPCR IN REAL TIME: TRANSMEMBRANE HELIX 6 RESETS AS ALL-TRANS RETINAL IS RELEASED FROM RHODOPSIN. Chrisopher T. Schafer , Jay M. Janz, David L. Farrens 544-P os B oard #B299 ENGINEERING THE ENDOTHELIN A AND B RECEPTORS USING A SOLUBLE TEMPLATE FOR STRUCTURAL ANALYSIS AND SMALL MOLECULE SCREENING. Joshua A. Weiner , Christopher O. Audu, Kristina Seitler, Maria Pellegrini, Dale F. Mierke 545-P os B oard #B300 INVESTIGATING EGF RECEPTOR SIGNALING DYNAMICS WITH PATTERNED LIGAND SURFACES. Devin Wakefield , Amit Singhai, David Holowka, Barbara Baird 546-P os B oard #B301 DECIPHERING REGULATORY MECHANISM OF THE JUX- TAMEMBRANE REGION IN THROMBOPOIETIN RECEPTOR ACTIVATION. Shao-Qing Zhang , Jing Jiang, Gozde Ulas, Yibing Wu, Wei Tong, William F. DeGrado 547-P os B oard #B302 FGF1 AND FGF2 INDUCED FGFR3 DIMERIZATION IN PLASMA MEMBRANE DERIVED VESICLES. Sarvenaz Sarabipour , Kalina Hristova 548-P os B oard #B303 VOLTAGE AFFECTS THE DISSOCIATION RATE CONSTANT OF THE M2 MUSCARINIC RECEPTOR. Yair Ben Chaim , Shimrit Bochnik, Itzchak Parnas, Hanna Parnas 549-P os B oard #B304 CROSS-SIGNALING BETWEEN THE METABOTROPIC GLUTAMATE 2 RECEPTOR AND THE SEROTONIN (5-HT) 2A RECEPTOR IN HEK-293 CELLS. Lia Baki, Jason Younkin , Jose Miguel Eltit, Miguel Fribourg, Gyu Park, Zhanna Vysotskaya, Diomedes E. Logothetis 550-P os B oard #B305 SINGLE PROTEOLIPOSOME ASSAY TO MONITOR OPSIN AND CANNABINOID GPCR HOMO-OLIGOMERIZATION. Samuel M. Walsh , Signe Mathiasen, Jonathan F. Fay, David L. Farrens, Dimitrios Stamou 551-P os B oard #B306 USE OF BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) FOR STUDIES OF PROTEIN-PROTEIN INTERACTIONS BETWEEN THE GLUD2 RECEPTOR AND INTRACELLULAR INTERACTION PARTNERS. Helle B. Krog , Anders Skov Kristensen 552-P os B oard #B307 MULTIDIMENSIONAL SOLID-STATE NMR OF FUNCTIONAL CHEMOTAXIS RECEPTOR SIGNALING COMPLEXES. Michael J. Harris , Robert M. Weis, Jochem O. Struppe, Benjamin J. Wylie, Ann E. McDermott, Lynmarie K. Thompson 553-P os B oard #B308 MECHANISMS UNDERLYING CAMKII REGULATION OF ASTROCYTIC GLUTAMATE TRANSPORTERS. Aarti Chawla , Derrick Johnson, Andy Hudmon 554-P os B oard #B309 OPTIMIZED ZEBRAFISH APOLIPOPROTEIN A-I EXPRESSION AND PURIFICATION FOR NABBS ASSEMBLY. Carlos A. Rico , Thomas P. Sakmar, Thomas Huber

555-P os B oard #B310 VOLTAGE DEPENDENCE OF MUSCARINIC M 1 -,M 3 - AND M 5 RECEPTORS. Andreas Rinne , Juan-Carlos Mobarec, Peter Kolb, Moritz Bünemann 556-P os B oard #B311 A MOLECULAR-LEVEL INVESTIGATION OF THE EFFECT OF SODIUM IONS ON THE BINDING OF OPIOID LIGANDS TO THEIR RECEPTORS. Yi Shang , Valerie Le Rouzic, Gavril W. Pasternak, Marta Filizola 557-P os B oard #B312 ALLOSTERIC REGULATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR. Atrish Bagchi , Nicholas J. Bessman, Neo Z. Wu, Lily Raines, Zhongyuan Kan, Wenbing Hu, S. Walter Englander, Daniel J. Leahy, Mark A. Lemmon, Kathryn M. Ferguson 558-P os B oard #B313 BIOPHYSICAL PROPERTIES OF 2-ARACHIDONOYLGLYCEROL IN A LIPID MATRIX AND ITS BINDING TO RECOMBINANT CANNABINOID RECEPTOR CB 2 . Tomohiro Kimura , Mihaela Mihailescu, Diane L. Lynch, Nadukkudy V. Eldho, Patricia H. Reggio, Alexei A. Yeliseev, Klaus Gawrisch  Ryanodine and IDP Receptors (Boards #B314–#B338) 559-P os B oard #B314 THE CARDIAC RYANODINE RECEPTOR (RYR2): INVESTIGATING MECHANISMS OF GATING AT THE SELECTIVITY FILTER. Jahn M. Firth , Joanne Euden, Alan J. Williams 560-P os B oard #B315 LOOKING FOR THE CALCIUM-BINDING SITE IN THE RYANODINE RECEPTOR`S VESTIBULE. Janos Almassy , Sandor Sarkozi, Istvan Jona 561-P os B oard #B316 LIGAND-DEPENDENT CONFORMATIONAL CHANGES IN THE CARDIAC RYANODINE RECEPTOR. Yingjie Liu , Xixi Tian, Ruiwu Wang, Terence Wagenknecht, Zheng Liu, Suirong Wayne Chen 562-P os B oard #B317 STRUCTURE-FUNCTION RELATIONSHIP OF CALCINS, A FAMILY OF HIGH-AFFINITY PEPTIDE LIGANDS OF RYANODINE RECEPTORS. Liang Xiao , Georgina B. Gurrola, Jing Zhang, Mario San Martin, Fernando Z. Zamudio, Lourival D. Possani, Héctor H. Valdivia 563-P os B oard #B318 MAPPING THE INTERACTING SITES MEDIATING TETRAMERISATION OF RYANODINE RECEPTOR AMINO-TERMINUS. Monika Seidel, Paulina J. Stanczyk , F Anthony Lai, Spyros Zissimopoulos 564-P os B oard #B319 FRET-BASED TRILATERATION OF A DOMAIN PEPTIDE BOUND WITHIN FUNCTIONAL RYANODINE RECEPTORS IN CARDIOMYOCYTES. Bengt Svensson , Tetsuro Oda, Florentin R. Nitu, Iustin Cornea, Donald M. Bers, David D. Thomas, Razvan L. Cornea 565-P os B oard #B320 EVOLUTION, STRUCTURE AND FUNCTION OF RYANODINE RECEPTOR DOMAINS. Zhiguang Yuchi , Filip Van Petegem

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Biophysical Society 58 th Annual Meeting, San Francisco, California