BPS Program Book 2014

612-P os B oard #B367 TRANSMURAL GRADIENT OF ITO AND INAK PROFOUNDLY INFLUENCE VENTRICULAR ACTION POTENTIAL DURATION. Yunliang Zang , Ling Xia, Ye Chen-Izu, Leighton Izu 613-P os B oard #B368 MECHANO-CHEMOTRANSDUCTION IN THE SINGLE CARDIAC MYOCYTE CONTRACTING IN 3D ELASTIC GEL. Rafael Shimkunas , Zhong Jian, Wenwu Xiao, Yuanpei Li, Yi-Je Chen, John Shaw, Nipavan Chiamvimonvat, Leighton T. Izu, Kit S. Lam, Ye Chen-Izu 614-P os B oard #B369 FUNCTIONAL INTERACTION WITH FILAMIN A ENHANCES ATRIAL-SPECIFIC SMALL CONDUCTANCE CA2 ACTIVATED K + CHANNEL (SK2) SURFACE MEMBRANE EXPRESSION. Sassan Rafizadeh, Zheng Zhang , Ryan Woltz, Hyo J. Kim, Ling Lu, Dipika Tuteja, Anil Singapuri, Amir A. Bigdeli, Sana B. Harchache, Anne A. Knowlton, Ebenezer N. Yamoah, Vladimir Yarov-Yarovoy, Nipavan Chiamvimonvat 615-P os B oard #B370 A-ACTININ2 AND FILAMIN A CYTOSKELETAL INTERACTING PROTEINS FACILITATE SK2 CHANNELS RECYCLING FROM ENDOSOMES TO THE SURFACE MEMBRANE. Zheng Zhang , Sassan Rafizadeh, Hyo J. Kim, Ling Lu, Rachit Anand, Sarasa Kim, Ebenezer N. Yamoah, Nipavan Chiamvimonvat 616-P os B oard #B371 CRITICAL ROLES OF SK3 CALCIUM-ACTIVATED POTASSIUM CHANNELS INTHE REPOLARIZATION OF ATRIAL MYOCYTES. Xiao-Dong Zhang , Valeriy Timofeyev, Ning Li, Daimin Zhang, Richard Myers, Anil Singapuri, Chris Bond, John Adelman, Deborah Lieu, Nipavan Chiamvimonvat 617-P os B oard #B372 TARGETED DELETION OF KCNE4 IMPAIRS VENTRICULAR REPOLARIZATION IN MICE. Shawn M. Crump , Zhaoyang Hu, Ritu Kant, Daniel I. Levy, Geoffrey W. Abbott 618-P os B oard #B373 ATRIAL AND VENTRICULAR MYOCYTES HAVE DIFFERENT ARRHYTHMOGENIC PROFILES IN RESPONSE TO OXIDATIVE STRESS AND HYPOKALEMIA. Thao P. Nguyen , James N. Weiss 619-P os B oard #B374 ACTIVATION OF SMALL CONDUCTANCE CALCIUM-ACTIVAT- ED POTASSIUM CHANNELS BY SARCOPLASMIC RETICULUM CALCIUM RELEASE ATTENUATES DELAYED AFTERDEPOLARIZATIONS IN VENTRICULAR MYOCYTES. Dmitry Terentyev, Jennifer A. Rochira, Radmila Terentyeva, Karim Roder, Gideon Koren, Weiyan Li 620-P os B oard #B375 ACTION POTENTIAL CONDUCTION VELOCITY IS INCREASED BY RAISED INTRACELLULAR CAMP IN THE INTACT RAT HEART VIA A CAMKII MEDIATED PATHWAY. Annabel S. Campbell , Francis L. Burton, George S. Baillie, Godfrey L. Smith 621-P os B oard #B376 ACTION POTENTIAL SHAPE DIFFERENCES SET SPECIES- DEPENDENT β -ADRENERGIC-STIMULATION RESPONSE. Luca Sala , Bence Hegyi, Chiara Bartolucci, Claudia Altomare,

622-P os B oard #B377 DIFFERENTIAL REGULATION OF SLOW AND RAPID DELAYED RECTIFIER POTASSIUM CURRENTS BY CGMP DEPENDENT NITRIC OXIDE SIGNALLING PATHWAYS IN ISOLATED ADULT GUINEA PIG VENTRICULAR MYOCYTES. Rachel E. Caves , Kieran Brack, André Ng, John Mitcheson 623-P os B oard #B378 A TREK-LIKE K + CHANNEL CURRENT INHIBITED BY NOREPINEPHRINE IN RAT ATRIAL MYOCYTES. Richard C. Bond, Stephanie C. Choisy, Simon M. Bryant, Jules C. Hancox, Andrew F. James 624-P os B oard #B379 MODULATION OF K 2P K + LEAK CHANNEL SENSITIVITY TO CARVEDILOL BY ALTERNATIVE MRNA TRANSLATION INITIATION. Jana Kisselbach, Claudia Seyler, Patrick A. Schweizer, Hugo A. Katus, Dierk Thomas 625-P os B oard #B380 L-TYPE CALCIUM AND POTASSIUM CURRENTS ARE DIFFERENTLY REGULATED BY ANGIOTENSIN II IN ATRIAL AND VENTRICULAR MOUSE MYOCYTES. Anh-Tuan Ton , Francois Huynh, Mona Nemer, Celine Fiset 626-P os B oard #B381 NONLINEAR BEHAVIOR OF CONDUCTION IN CARDIAC TISSUE WITH HETEROGENEOUS EXPRESSION OF CONNEXIN 43. Yann Prudat , Jan P. Kucera 627-P os B oard #B382 IKR IMPACT ON REPOLARIZATION AND ITS VARIABILITY ASSESSED BY DYNAMIC-CLAMP. Claudia Altomare , Luca Sala, Chiara Bartolucci, Gaspare Mostacciuolo, Stefano Severi, Antonio Zaza 628-P os B oard #B383 REDUCING OXIDATIVE STRESS AND CAMKII ACTIVITY AS AN ANTIARRHYTHMIC STRATEGY IN WOODCHUCKS IN WINTER. Hairuo Wen, Lin Yan, Raymond K. Kudej, Nadezhda Fefelova, Richard Gordan, Dorothy Vatner, Stephen Vatner, Lai-Hua Xie 629-P os B oard #B384 A NOVEL CARDIAC NAV1.5 CHANNEL MUTATION, L812Q, LEADS TO BRUGADA SYNDROME. Lumin Wang , Xiangyun Meng, Zhenghang Zhao, Dehui Xu, David Fedida, Zhuren Wang, Chen Huang 630-P os B oard #B385 MEMBRANE CAPACITANCE CHANGES DUE TO TEMPERATURE INCREASE IN RAT CARDIAC MYOCYTES. Matej Hotka , Ivan Zahradnik 631-P os B oard #B386 ELECTROPHYSIOLOGICAL AND STRUCTURAL LEFT VENTRICLE REMODELLING IN SPONTANEOUSLY HYPERTENSIVE RAT HEARTS: A MULTICELLULAR STUDY. Samha Alayoubi , Carolina Pinto Ricardo, Junaid Zaman, Priyanthi Dias, Patrizia Camelliti, Magdi H. Yacoub, Cesare Terracciano 632-P os B oard #B387 ALTERNANS IN RABBIT HEART DURING ACUTE REGIONAL ISCHEMIA: OPTICAL MAPPING AND MICROELECTRODE RECORDINGS. Irma Martišienė , Jonas Jurevičius, Rūta Vosyliūtė, Antanas Navalinskas, Rimantas Treinys, Regina Mačianskienė, Rimantas Benetis, Arvydas Matiukas, Arkady M. Pertsov

Marcella Rocchetti, Gaspare Mostacciuolo, Stefano Severi, Norbert Szentandrássy, Péter P. Nánási, Antonio Zaza

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Biophysical Society 58 th Annual Meeting, San Francisco, California