BPS Program Book 2014

9:00 am –7:00 pm , R oom 310 Subgroup Bioenergetics

5:20 pm

subgroup business meeting

7:00 pm

subgroup dinner

S A T U R D A Y

10:30 am –7:00 pm , R oom 135 Subgroup Intrinsically Disordered Proteins

Subgroup Co-Chairs Jan Hoek and György Hajnóczky, Thomas Jefferson University

Morning Symposium: Ion Channels of the InnerMitochondrial Membrane

Subgroup Chair Ashok Deniz, Scripps Research Institute

18-S ubg 9:00 am FOF1-ATP SYNTHASE DIMERS AND THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE FROM YEASTTOMAMMALS. Paolo Bernardi, Valentina Giorgio, Michela Carraro, Sophia von Stockum, Victoria Burchell, Justina Šileikytė, Valeria Petronilli, Mario Zoratti, Ildikò Szabò, Mike Forte, Giovanna Lippe 19-S ubg 9:30 am THE C-SUBUNIT OF THE ATP SYNTHASE FORMS THE PORE OF THE PTP. Elizabeth Jonas , Silvio Sacchetti, Han-A Park, Emma Lazrove, Gisela Beutner, George A. Porter, Jr., Kambiz N. Alavian 10:00 am coffee break 20-S ubg 10:30 am MITOCHONDRIAL UNCOUPLING AND THERMOGENESIS. Yuriy V. Kirichok 21-S ubg 11:00 am NEW MITOCHONDRIAL POTASSIUM CHANNELS. Adam Szewczyk , Anna Olszewska, Bartlomiej Augustynek, Michal Laskowski, Piotr Bednaarczyk 22-S ubg 11:30 am INHIBITION OF A MITOCHONDRIAL POTASSIUM CHANNEL AS A NEW THERAPEUTIC STRATEGY FOR CHRONIC LYMPHOCYTIC LEUKEMIA. Ildikò Szabò, Luigi Leanza, Antonella Managò, Federica Frezzato, Kathrin Becker, Livio Trentin, Gianpietro Semenzato, Erich Gulbins, Mario Zoratti 1:40 pm young investigator award presentation Afternoon Symposium: Post-translational Modifications of Mitochondrial Proteins 23-S ubg 2:00 pm PROTEIN ACYLATION REGULATES METABOLISM. Matthew Hirschey N o A bstract 2:30 pm SIRT3-MEDIATED ACETYLATION OF MITOCHONDRIAL PROTEINS. Eric Verdin 3:00 pm coffee break N o A bstract 3:30 pm PKA Signaling at the Mitochondria. Susan Taylor 24-S ubg 4:00 pm REGULATION OF MITOCHONDRIAL PROTEIN FUNCTION BY PTMS DURING ACUTE AND CHRONIC NUTRIENT STRESS. David Pagliarini N o A bstract 4:30 pm CARDIAC-MITOCHONDRIA: NUTRIENT SENSORS FOR REDOX-DRIVEN METABOLIC REPROGRAMMING. Luke Szweda

Intrinsic Protein Disorder: Structure and Mechanisms

10:30 am

subgroup business meeting

25-S ubg 1:00 pm FOLDING UPON BINDING-IS IT JUST A SIMPLE PROTEIN FOLDING PROBLEM? Jane Clarke, Keynote Speaker 26-S ubg 1:45 pm INSIGHTS INTO THE BINDING MECHANISM OF IDPS FROM MOLECULAR SIMULATION. Robert Best 2:10 pm postdoc talk 27-S ubg 2:25 pm ACCESSIBLE CONFORMATIONS OF N-TERMINAL ACETYLATED ALPHA-SYNUCLEIN: IMPLICATIONS FOR FIBRIL FORMATION. Jean Baum 28-S ubg 2:50 pm DIVERSE TRANSIENT STRUCTURES IN SMALL OLIGOMERS OF α -SYNUCLEIN PROBED BY SINGLE-MOLECULE FORCE SPECTROSCOPY. Michael Woodside 3:15 pm coffee break 29-S ubg 3:45 pm CONTROL OF DISORDER AND ORDER IN SIGNALING BY PROTEINS. Richard Kriwacki 30-S ubg 4:10 pm NMR STUDIES OF THE FREE ENERGY LANDSCAPE OF INTRINSICALLY DISORDERED PROTEINS IN THEIR FREE AND BOUND FORMS. Martin Blackledge 4:35 pm postdoc talk 31-S ubg 4:50 pm LINKING INTRINSIC DISORDER TO ALLOSTERIC REGULATION IN THE NMDA RECEPTOR. Mark Bowen 32-S ubg 5:15 pm DECODING SEQUENCE-ENSEMBLE RELATIONSHIPS OF IDPS. Rohit Pappu 7:00 pm subgroup dinner

12:00 pm –6:00 pm , R oom 304 Subgroup Nanoscale Biophysics

Subgroup Chair Victoria Birkedal, Aarhus University, Denmark 33-S ubg 12:00 pm NANOSCALE MECHANISMS UNDERLYING HIV-1 VIRAL PARTICLE ASSEMBLY AND RELEASE. Jennifer Lippincott-Schwartz , Prabuddha Sengupta, Antony Chen, Schuyler van Engelenburg

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Biophysical Society 58 th Annual Meeting, San Francisco, California