BPS Program Book 2014

 Protein Gymnastics (Boards #B1–#B26) 1271-P os B oard #B1 TRYPSINOGEN ACTIVATION OBSERVED IN ACCELERATED MOLECULAR DYNAMICS SIMULATIONS. Leonardo Boechi , J. Andrew McCammon 1272-P os B oard #B2 CONFORMATIONAL STATES AND DYNAMICS OF NEURONAL CALCIUM SENSOR SYNAPTOTAGMIN. Maria Bykhovsksia 1273-P os B oard #B3 ACTIVE OUTPUT STATE OF THE SYNECHOCOCCUS KAI CIRCADIAN OSCILLATOR. Mark Paddock , Joseph Boyd, Susan Golden 1274-P os B oard #B4 DETERMINATION OF THE DYNAMIC STRUCTURES OF IGG ANTIBODY BY INDIVIDUAL-PARTICLE ELECTRONTOMOGRAPHY. Xing Zhang , Lei Zhang, Matthew J. Rames, Gang Ren 1275-P os B oard #B5 PULSED EPR DISTANCE MEASUREMENTS RESOLVE THE IMPACT OF SITE-SPECIFIC CALMODULIN METHIONINE OXIDATION. Megan McCarthy, Michael Olenek, Mitch Reuter, Rebecca Moen, David D. Thomas, Jennifer C. Klein 1276-P os B oard #B6 OXIDATIVE STRESS MODULATES BIOACTIVITY OF LYMPHOTOXIN, BUT NOT TNF, THROUGH SITE-SPECIFIC OXIDATION OF METHIONINE RESIDUES. Andrew K. Lewis , Jonathan N. Sachs 1277-P os B oard #B7 ASSESSING DYNAMIC FEATURES OF NF- κ B VIA MOLECULAR DYNAMICS SIMULATIONS AND ELASTIC NETWORK MODEL. Arzu Uyar , Vineet Pande, Cameron Mura, J. Andrew McCammon, Pemra Doruker, Lennart Nilsson 1278-P os B oard #B8 CONFORMATIONAL PROPERTIES OF KINESIN’S NECK LINKER ACROSS SPECIES. Jason Doornenbal , Intisar Shaheed, Amanda Miguel, David Ando, Ajay Gopinathan 1279-P os B oard #B9 CONFORMATIONAL CHANGES IN THE β SUBUNITS OF |F 1 -ATPASE REVEALED BY FRET MEASUREMENTS DURING THE ROTATION OF THE γ SUBUNIT. Mitsuhiro Sugawa , Masaru Kobayashi, Takashi Matsui, Tomoko Masaike, Takayuki Nishizaka 1280-P os B oard #B10 EFFECTS OF PHOSPHOMIMETIC MUTATIONS ON THE PERSISTENCE LENGTH AND THIN FILAMENT BINDING PROPERTIES OF α AND ß-TROPOMYOSIN. Greg Medlock , Worawit Suphamungmee, An-Yue Tu, Xiaochuan (Edward) Li, Michael Regnier, Michael A. Geeves, William Lehman 1281-P os B oard #B11 DYNAMICS IN THE TRANSMEMBRANE SEGMENT OF THE INFLUENZA A M2 PROTON CHANNEL. Joana Paulino , Ivan Hung, Tymothy A. Cross 1282-P os B oard #B12 ROTATION TRIGGERS NUCLEOTIDE-INDEPENDENT CONFORMATIONAL TRANSITION OF THE EMPTY BETA SUBUNIT OF F1-ATPASE. Jacek Czub , Milosz Wieczor, Adrian Tobiszewski, Helmut Grubmueller

1283-P os B oard #B13 INTERDOMAIN DYNAMICS OF PHOSPHOGLYCERATE KINASE STUDIED BY SINGLE-MOLECULE FRET AND A MESOSCALE HYDRODYNAMICS SIMULATION. Matteo Gabba , Simon Poblete, Daryan Kempe, Antonie Schöne, Tina Züchner, Gerhard Gompper, minority affairs travel awardee DETERMINANTS OF FIBRINOLYSIS IN SINGLE FIBRIN FIBERS. Igal Bucay , Steven D. Wulfe, Nathan E. Hudson, Tim O’Brien, Mike R. Falvo 1285-P os B oard #B15 INTERNAL MOTIONS PRIME CIAP1 FOR RAPID ACTIVATION. Aaron H. Phillips , Allyn J. Schoeffler, Tsutomu Matsui, Thomas Weiss, Erin C. Dueber, Wayne J. Fairbrother 1286-P os B oard #B16 THE FREE ENERGY CONTRIBUTION OF SH3 AND SH2 IN C-ABL 1B AUTOINHIBITIONMECHANISMVIA A COMPUTATIONAL STRUCTURE-BASED MODEL. Ilaria Mereu , Ludovico Sutto, Francesco L. Gervasio 1287-P os B oard #B17 SINGLE MOLECULE OBSERVATION OF F1-ATPASE USING ARTIFICIAL SUBSTRATE AND AMINO ACID. Ayako Yukawa , Ryu John Iwatate, Rikiya Watanabe, Mako Kamiya, Ryota Iino, Shigehiko Hayashi, Yasuteru Urano, Hiroyuki Noji 1288-P os B oard #B18 ACTIVATION CYCLE OF G α S PROTEIN ELUCIDATED BY ELASTIC NETWORK BASED SIMULATION. Minhyeok Kim, Youngjin Kim, Jaeboong Choi, Byeongsoo Lim, Moon K. Kim 1289-P os B oard #B19 THE STATISTICAL CONFORMATION OF A HIGHLY FLEXIBLE PROTEIN: SMALL ANGLE X-RAY SCATTERING OF S. AUREUS PROTEIN A. Jo A. Wiersma Capp , Terrence G. Oas 1290-P os B oard #B20 LSD1/COREST - H3-HISTONE MOLECULAR RECOGNITION: INTER-DOMAIN MOTIONS IN AN ALLOSTERIC NANOSCALE CLAMP REVEALED BY COMPUTER SIMULATIONS. Nadeem Ahmad Vellore , Riccardo Baron 1291-P os B oard #B21 STRUCTURAL DYNAMICS OF THE HUMAN MRP1 DRUG TRANSPORTER REVEALED BY FLUORESCENCE RESONANCE ENERGY TRANSFER. Surtaj H. Iram , Seth L. Robia 1292-P os B oard #B22 PROBING THE OUTER MEMBRANE OF PSEUDOMONAS AERUGINOSA USING MOLECULAR DYNAMICS SIMULATIONS. Jamie Parkin , Tim Carpenter, Syma Khalid 1293-P os B oard #B23 UNDERSTANDING COLICIN N IMPORT INTO GRAM NEGATIVE BACTERIAL CELLS USING SMALL ANGLE NEUTRON SCATTERING. Wanatchaporn Arunmanee , Alexandra Solovyova, Christopher L. Johnson, Richard K. Heenan, Jeremy H. Lakey 1294-P os B oard #B24 AFFINITIES OF SELECTIVE-SEROTONIN REUPTAKE INHIBITOR (SSRI) FOR HUMAN TRANSPORTERS: MOLECULAR MODELING AND QUANTUM CHEMICAL STUDIES. Krishna Deepak , Alok Jain, Ramasubbu Sankararamakrishnan Jörg Fitter 1284-P os B oard #B14

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Biophysical Society 58 th Annual Meeting, San Francisco, California