BPS2024 Full Program & Abstracts

1181-Pos Board B134 COMPUTATIONAL STUDY OF RNA BINDING BY A SHORT INTRINSICALLY DISORDERED PROTEIN. Emery T. Usher , Rishav Mitra, James C. Bardwell, Alex S. Holehouse 1182-Pos Board B135 UNVEILING SUBMICRON NANOCLUSTERS UNDERLYING FUS PHASE SEPARATION. Yingda Ge , Sua Myong 1183-Pos Board B136 THE CRITICAL ROLE OF THE PROLINE RICH REGION (PRR) OF TAU IN PHYSIOLOGICAL MICROTUBULE ASSEMBLY AND ALZHEIMER’S DISEASE PATHOLOGY. Christopher R. Brue , Karen Acosta, Elizabeth Rhoades 1184-Pos Board B137 HTRA1: A MULTIPRONGED INHIBITOR AGAINST ALPHA SYNUCLEIN AG GREGATION. Priscilla Chinchilla , Baifan Wang, Xue Yang, Sagar D. Khare, Jean Baum 1185-Pos Board B138 MEMBRANE-ASSISTED AGGREGATION OF AΒ40. Fidha Nazreen Kunnath Muhammedkutty , Huan-Xiang Zhou 1186-Pos Board B139 FLANKING DOMAINS MODULATE Α-SYNUCLEIN MONOMER STRUC TURE: A DOMAIN DELETION STUDY. Noriyo Onishi, Frank X. Vázquez 1187-Pos Board B140 Travel Award Winner ATP MEDIATES PHASE SEPARATION OF DISORDERED BASIC PROTEINS BY BRIDGING INTERMOLECULAR INTERACTION NETWORKS. Divya Kota , Ramesh Prasad, Huan-Xiang Zhou 1188-Pos Board B141 USING HDX-MS AND FPOP-MS/MS TO IDENTIFY STRUCTURAL DIFFER ENCES IN INTRINSICALLY DISORDERED REGIONS OF NFKB AND IΚBΑ UPON BINDING. Luis Oliva 1189-Pos Board B142 MODULATING MATERIAL PROPERTIES OF CARGO PROTEIN TO PROBE EXOPHER BIOLOGY. Edward Chuang , Mayur Barai, Benjamin S. Schuster, Monica Driscoll 1190-Pos Board B143 OUTCOMES OF ACETYLATION AND NITRATION FOR ALPHA-SYNUCLEIN’S MEMBRANE BINDING AND PHASE BEHAVIOR. Sadie C. Kim, Jean R. Katz , Alana T. Ponte, Casey H. Londergan 1191-Pos Board B144 SEQUENCE-SPECIFIC INSIGHTS INTO THE TIME-DEPENDENT MATERIAL PROPERTIES OF BIOMOLECULAR CONDENSATES. Mayur Barai , Emily Pinlac, Shiv Rekhi, Cristobal Garcia, Kristi Kiick, Jeetain Mittal, Benjamin Schuster Condensates in Physiology and Disease (Boards B145 - B167) 1192-Pos Board B145 INFLAMMATION REGULATION IN AIRWAY EPITHELIUM IN HEALTH AND DISEASE. Carlie Klatt, Asmahan AbuArish 1193-Pos Board B146 HYPEROSMOTIC STRESS ALTERS ENZYME STOICHIOMETRY OF GLUCO SOMES. Haotian Wu , Prashanta Sharma Roy, Songon An, Minjoung Kyoung

1194-Pos Board B147 REGULATION OF STRESS GRANULES BY OGLCNACYLATION IN STRESSED AND ISCHEMIC CARDIOMYOCYTES. Hannah C. Swimm , Wenxi Zhang, Yashas Mallikarjun, Deepthi Ashok, D. Brian Foster, Brian O’Rourke, Natasha Zachara, Kyriakos Papanicolaou 1195-Pos Board B148 NUCLEAR-IMPORT RECEPTOR TNPO1 AS MODULATOR OF ABERRANT PHASE TRANSITIONS. Miriam Linsenmeier , Charlotte Fare, James Shorter 1196-Pos Board B149 INVESTIGATING THE FUNCTION OF THE MULTIPHASE ORGANIZATION OF THE NUCLEOLUS. Aya A. Abu-Alfa , Sofi A. Quinodoz, Lifei Jiang, Clifford P. Brangwynne 1197-Pos Board B150 INVESTIGATING THE TRANSCRIPTIONAL ROLE OF FUSION TFE3 CON DENSATES IN ONCOGENESIS. Ye Jin Lee , Choon Leng So, Danfeng Cai 1198-Pos Board B151 PROBING NUCLEAR HSATII BIOMOLECULAR CONDENSATES. Thembala mi Dube , Christina A. Rabeler, Dawn M. Carone 1199-Pos Board B152 RNA CONDENSATION FLUIDIZES THE CYTOPLASM. Ying Xie , Tiewei Liu, David Gresham, Liam J. Holt 1200-Pos Board B153 PHASE SEPARATION AND AGGREGATION OF Α-SYNUCLEIN DIVERGE AT DIFFERENT SALT CONDITIONS. Rebecca Sternke-Hoffmann, Xun Sun, Andreas Menzel, Michael Wördehoff, Wolfgang Hoyer, Wenwei Zheng , Jinghui Luo 1201-Pos Board B154 BIOCHEMICAL SIGNALING ENCODED IN EMERGENT PROPERTIES. Jer emy D. Schmit 1202-Pos Board B155 CHAPERONE-DEPENDENT AGING OF SINGLE HEAT SHOCK-INDUCED RI BOSOMAL PROTEIN CONDENSATES. Maya G. Igarashi , Olivia C. Schaffer, Asif Ali, Kyle Lin, Diangen Lin, David Pincus, Allison Squires 1203-Pos Board B156 SINGLE-MOLECULE IMAGING TO REVEAL HOW CHAPERONES ENGAGE NATIVE CONDENSATES. Kyle M. Lin , Diangen (Dana) Lin, Haneul Yoo, David A. Drummond, Allison Squires 1204-Pos Board B157 BIOMOLECULAR CONDENSATES AGING INHIBITION, A COMPUTATIONAL APPROACH. Ignacio Sanchez Burgos , Jorge R. Espinosa 1205-Pos Board B158 Travel Award Winner SINGLE-MOLECULE STUDY OF DISAGGREGATION OF BIOMOLECULAR CONDENSATES BY HEAT SHOCK PROTEINS. Diangen Lin , Kyle M. Lin, David A. Drummond, Allison H. Squires 1206-Pos Board B159 INTERPLAY BETWEEN WATER-MEDIATED AND DIRECT INTERACTIONS AND THE ORGANIZATION OF PEPTIDE CONDENSATES. William Brown 1207-Pos Board B160 UNRAVELING THE ROLE OF FUS IN DNA DAMAGE INDUCED BY TOPOI SOMERASE-I INHIBITOR. Xincheng Yuan , Nathalie A. Djaja, Sua Myong 1208-Pos Board B161 UNRAVELING PHASE BEHAVIOR OF FOLDED PROTEINS AND RNA VIA SIMULATION. Alexander Jussupow , Thong Van, Divya Bartley, Lisa J. Lapidus, Michael Feig

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