BPS2024 Full Program & Abstracts

1393-Pos Travel Award Winner BINDING MECHANISM OF 4AP IN HKV1.5 CHANNEL: A MOLECULAR DYNAMIC SIMULATION STUDIES. Md Harunur Rashid , Ramisha Anan Rahman, bushra zaman, Rezwana Ahmed 1394-Pos Board B347 ON THE LOCALIZATION & COMPOSITION OF BK CHANNEL PORE GATE: SELECTIVITY FILTER VS LIPID OCCLUSION OF DEEP PORE. Kunal R. Shah 1395-Pos Board B348 HYPERPOLARIZATION-ACTIVATED CYCLIC-NUCLEOTIDE SENSITIVE CHAN NEL EXPRESSION IN THE PRE-BOTZINGER COMPLEX OF THE MEDUL LA. Rebecca Roth, Cathy Proenza, Nathan E. Schoppa, Colin H. Peters 1396-Pos Board B349 PHYLOGENETIC AND FUNCTIONAL ANALYSES OF COMB JELLY SHAKER K + CHANNELS REVEAL INDEPENDENT EVOLUTION OF VOLTAGE-GATED K + CHANNEL DIVERSITY. Benjamin T. Simonson , Max Jegla, Joseph F. Ryan, Timothy J. Jegla 1397-Pos Board B350 GATING THE K V 1.2 CHANNEL: A PROTON TRANSFER CHAIN OF STEPS FROM DONOR TO ACCEPTOR BY PROTONS THROUGH THE S4-S5 LINKER TO THE GATE. Alisher M. Kariev, Michael E. Green 1398-Pos Board B351 COOPERATIVE EFFECT OF POTASSIUM CHANNEL CAVITIES AND SELEC TIVITY FILTERS IN ION SELECTIVITY AND IONIC CURRENT RECTIFICA TION. Alisher M. Kariev , Michael E. Green 1399-Pos Board B352 INFLUENCE OF ACTION POTENTIAL AMPLITUDE AND FREQUENCY ON INACTIVATION OF VOLTAGE-GATED POTASSIUM (KV) CHANNELS. Juliane Deroy-Gagnon 1400-Pos Board B353 MOLECULAR MECHANISM OF KV1.3 INACTIVATION: INSIGHTS FROM NANOBODY BINDING AND MUTATIONAL ANALYSIS. Purushotham Selva kumar , Ana I. Fernández-Mariño, Joel R. Meyerson, Kenton Swartz 1401-Pos Board B354 MECHANISM OF EAG1 CHANNEL INHIBITION BY IMIPRAMINE BINDING TO THE PAS DOMAIN. Ze-Jun Wang , Mahdi Ghorbani, Xi Chen, Purush ottam Tiwari, Jeffery B. Klauda, Tinatin I. Brelidze 1402-Pos Board B355 LRMP INHIBITS THE CAMP-DEPENDENCE OF HCN4 CHANNELS BY DISRUPTING INTRAMOLECULAR SIGNAL TRANSDUCTION. William G. Nichols , Colin H. Peters, Rohit K. Singh, Avery Langley, Hannah R. Ferris, Danielle Jeffrey, John Bankston, Cathy Proenza 1403-Pos Board B356 MOLECULAR AND ELECTROPHYSIOLOGICAL CHARACTERIZATION OF NOCICEPTIVE SCHWANN CELLS. Maia Moog , Angela Ballesteros, Patrik Ernfors, Kenton Swartz 1404-Pos Board B357 CONCATENATED TANDEM CONSTRUCTS OF BK CHANNELS REVEAL THREE DISTINCT TYPES OF SUBUNIT STOICHIOMETRY IN CHANNEL MODULATION BY THE AUXILIARY Γ SUBUNIT AND MUTATIONS IN THE CHANNEL PORE REGION. Guanxing Chen 1405-Pos Board B358 SPATIAL DISTRIBUTION AND DYNAMICS OF KV1.3 CHANNELOSOME AT THE IMMUNOLOGICAL SYNAPSE. Jesusa Capera-Aragones, Maria Na varro Perez , Anna Benavente-Garcia, Michael L. Dustin, Antonio Felipe Board B346

1406-Pos Board B359 COMPUTATIONAL MAPPING OF ALLOSTERIC MODULATORS OF THE BK CHANNEL: SILCS IN LARGE SYSTEMS. Erik B. Nordquist , Mingtian Zhao, Wenbo Yu, Frank T. Horrigan, Alexander D. MacKerell 1407-Pos Board B360 A GATE AT THE SELECTIVITY FILTER TURNS AN INACTIVATED KV CHANNEL INTO A NON-SELECTIVE HYPERPOLARIZATION ACTIVATED CHANNEL. Bernardo I. Pinto , Carlos Alberto Z. Bassetto Jr, Yichen Liu, Francisco Bezanilla 1408-Pos Board B361 AN ISOLEUCINE LEVER IN S4-S5 LINKER AND THE ELECTROMECHANICAL VSD-PD COUPLING IN SHAKER . Carlos Alberto Z. Bassetto Jr , Francisco Board B362 INTRODUCTION OF A BUNGAROTOXIN BINDING SITE INTO EXTRACEL LULAR DOMAINS OF HCN4 CHANNELS. Daniel J. Enders , William G. Nichols, Avery A. Langley, Danielle M. Heebner, Matt J. Graham, Colin H. Peters, Cathy Proenza, Kurt G. Beam 1410-Pos Board B363 NEW INSIGHTS INTO THE BINDING OF TRIP8B PROTEIN TO THE CNBD OF HCN CHANNELS. Alessandro Porro , Andrea Saponaro, Roberta Castelli, Federico Thei, Dario DiFrancesco, Gerhard Thiel, Anna Moroni 1411-Pos Board B364 ANALOGOUS STRUCTURAL, ELECTRICAL, MECHANICAL AND OPTICAL FEATURES OF BLUE PHASES AND VOLTAGE SENSITIVE ION CHANNELS. H. Richard Leuchtag Ion Channel Regulatory Mechanisms (Boards B365 - B399) 1412-Pos Board B365 REGULATION OF VOLTAGE-GATED PROTON CHANNELS BY MEMBRANE LIPIDS. Shuo Han, Sarah Applewhite, Shuyi Wang, Grace Wang, Shizhen Wang 1413-Pos Board B366 THE EXTRACELLULAR DOMAIN OF EMILIANIA HUXLEYI H V 1 MEDIATES ZINC BINDING AND REGULATES CHANNEL FUNCTION. Emelia Melvin, Pavla Vaňková, Petr Man, Moshe Giladi, Yoni Haitin 1414-Pos Board B367 PIP 2 DRIVEN CYTOPLASMIC DOMAIN MOTIONS COUPLED TO KIR2 CHANNEL GATING. Sun Joo Lee , Eva-Maria Plessl, Anna Stary-Weinzing er, Colin G. Nichols 1415-Pos Board B368 ALLOSTERIC GATING MECHANISMS OF INWARD RECTIFYING K + CHAN NEL 3.2 GUIDED BY DISEASE MUTATIONS. Anna Stary-Weinzinger , Theres Friesacher 1416-Pos Board B369 INTRINSICALLY DYNAMIC MECHANISM WITHIN SELECTIVITY FILTER CONTROLS ION CURRENT THROUGH K 2P 2.1 CHANNEL. Ruitao Jin , Ben Corry, Brian J. Smith, Sitong He 1417-Pos Board B370 DYNAMIC INTERPLAY OF THE PROXIMAL C-TERMINUS AND SELECTIV ITY FILTER REVEALS GATING AND PHARMACOLOGICAL MODULATION MECHANISMS IN TREK K 2P CHANNELS. Berke Türkaydin , Marcus Schewe, Elena B. Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz, Han Sun Bezanilla 1409-Pos

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