BPS2024 Full Program & Abstracts

1445-Pos Board B398 AN ENGINEERED POTASSIUM CHANNEL FOR THERMOGENETICS. Anna Moroni , Chiara Mercutio, Guido Rey, Bianca Piermaria, Roberta Leone, Alberto Russo, Monica Beltrame, Raffaella Tonini, andrea saponaro, Gerhard Thiel 1446-Pos Board B399 ELECTROCHEMICAL LINKAGE IN A SPERM-SPECIFIC HCN TRANSPORT ER. Kamalendu Pal , Sandipan Chowdhury Ion Channels, Pharmacology, and Disease I (Boards B400 - B418) 1447-Pos Board B400 Travel Award Winner INTRODUCING NZ-58, A POTENT INHIBITOR OF THE HUMAN VOLTAGE GATED PROTON CHANNEL. Ádám Fehér , Éva Korpos, Katinka Gyuris, Geraldo Domingos, Martina Piga, Tihomir Tomasic, Nace Zidar, Gyorgy Panyi, Zoltan Varga, Ferenc Papp 1448-Pos Board B401 HV1 PROTON CHANNEL DEFICIENCY PROTECTS AGAINST ATHEROSCLE ROSIS. Lu Lu Zhang, Xin Wu, Jianhua J. Liu, Sidhant Singla, Jiwang Chen, Liang Hong 1449-Pos Board B402 PSEUDOMONAS AERUGINOSA CORNEAL INFECTION IS REGULATED BYTHE HV1 VOLTAGE-GATED PROTON CHANNEL. Priscila A. Rodriguez, Jessica Abdelmeseh, Serena Abbondante, Michaela E. Marshall, Fran cesco Tombola , Eric Pearlman 1450-Pos Board B403 ANTAGONISTS OF TRANSIENT RECEPTOR POTENTIAL-MUCOLIPIN 1: A NEW THERAPEUTIC STRATEGY FOR CANCER THERAPY. Anna Mondini , Manuel Paina, Fernanda Ricci, Matteo Bessi, Serena Meini, Elisa Tinelli, Chiara Liberati, Maria Pia Catalani, Jean-Francois Rolland 1451-Pos Board B404 TMEM175: APPARENT DRUG POTENCIES ARE DIFFERENT IN LYSOSOMES AND PLASMA MEMBRANE. A COMPARATIVE STUDY EMPLOYING A NOVEL SCREENING TECHNOLOGY. Andre Bazzone, George Okeyo , Rocco Zerlotti, Nina Brinkwirth, Cecilia George, Maria Barthmes, Niels Fertig 1452-Pos Board B405 REVERSE GENETICS EVALUATION OF MECHANOSENSITIVE ION CHAN NELS INVOLVED IN THE JELLYFISH STINGING RESPONSE. Zeeshan Banday 1453-Pos Board B406 MECHANICAL ACTIVATION OF PIEZO1 CHANNELS USING HIGH THROUGHPUT ELECTROPHYSIOLOGY. Timothy Strassmaier , Nicoletta Murciano, Maria G. Rotordam, Nadine Becker, Melanie Bettale, Gregory Parsonage, Alexis Darras, Lars Kaestner, David J. Beech, Niels Fertig, Markus Rapedius, Andrea Bruggemann 1454-Pos Board B407 TARGETING THE FACILITATORY EFFECT OF CAMP ON HCN2 CHANNEL OPENING PROMOTES ANALGESIC ACTIONS. Andrea Saponaro , Santiago L. Lopez, Kimberly Gomez, Alessandro Porro, Gerhard Thiel, Rajesh Khanna, Anna Moroni 1455-Pos Board B408 EXPLORING THE BINDING SITE AND MECHANISM OF ACTION OF NS309, A SUPERAGONISTIC POSITIVE GATING MODULATOR FOR THE CALCIUM ACTIVATED POTASSIUM CHANNEL KCA3.1. Joshua Nasburg , Heike Wulff, Heesung Shim, Connor Dietrich

1456-Pos Board B409 IMPACT OF KCNE4 ON KV1.3 PHARMACOLOGY. Daniel Sastre, Magalí Colomer-Molera , Gregorio Fernandez-Ballester, Antonio Felipe 1457-Pos Board B410 Travel Award Winner INHIBITION OF K V 1.3-K V 1.X HETEROTETRAMERS BY K V 1.3-SPECIFIC INHIBITORY PEPTIDES. Muhammad Umair Naseem , Amna S. Al Olaimi, Dorothy C.C. Wai, Michael W. Pennington, Raymond S. Norton, Gyorgy Panyi 1458-Pos Board B411 Travel Award Winner FUNCTIONAL DIVERSITY OF PROLINE-SUBSTITUTION, EPILEPSY-ASSO CIATED, K V 1.2-CHANNEL VARIANTS. Panagiota Gkotsi, Amaia Jauregi Miguel , Serena Pozzi, Varsha Prakash, Dang Vu, Richard Hopkins, Ade line Ngoh, John E. Connolly, Derrick W.S. Chan, Antonios Pantazis 1459-Pos Board B412 ISOFORM SPECIFIC CONSEQUENCES OF CANTU SYNDROME K ATP CHAN NEL GAIN OF FUNCTION MUTATION SUR2 H60Y. Jian Gao , Colin G. Nichols 1460-Pos Board B413 DUAL CONTROL OF NEUROVASCULAR COUPLING BY ATP-SENSITIVE POTASSIUM CHANNELS. Nathaniel W. York , Ryan M. Bowen, Jonah Padawer-Curry, Adam Q. Bauer, Jin-Moo Lee 1461-Pos Board B414 GAIN-OF-FUNCTION MUTATIONS OF KATP CHANNELS ARE RESPONSIBLE FOR REDUCED SKELETAL MUSCLE PERFORMANCE IN A MURINE MODEL OF CANTÙ SYNDROME. Rosa Scala , Maya Mukadam, Courtney Frazier, Gretchen Meyer, Colin G. Nichols 1462-Pos Board B415 CHRONIC K ATP INHIBITION IN VIVO RESULTS IN DECREASED CA 2+ -SENSI TIVITY OF INSULIN SECRETION. Nathaniel W. York , Sumit Patel, Zihan Yan, Abbie L. Tate, Courtney Frazier, Maria S. Remedi, Colin G. Nichols 1463-Pos Board B416 ALLOSTERIC INHIBITION OF GIRK CHANNELS BY ETHOSUXIMIDE. Theres Friesacher , Boris Shalomov, Haritha P. Reddy, Harald Bernsteiner, John C. Combista, Shoham Dabbah, Daniel Yakubovich, Eva-Maria Plessl, Nathan Dascal, Anna Stary-Weinzinger 1464-Pos Board B417 ENGINEERING NOVEL PHARMACOLOGY FOR THE TREK1 K2P CHAN NEL. Leila Khajoueinejad , Paul M. Riegelhaupt 1465-Pos Board B418 Travel Award Winner THREE NEW TOXINS FROM THE SOUTH AMERICAN SPIDER PAMPHO BETEUS VERDOLAGA INHIBIT CALCIUM AND POTASSIUM CHANNEL CURRENTS OF MURINE CARDIOMYOCYTES. Jéssica Rojas-Palomino, Alejandro Gómez-Restrepo, Marco A. Giraldo, Juan C. Calderón Other Channels (Boards B419 - B430) 1466-Pos Board B419 Travel Award Winner PURIFICATION OF A NOVEL MGTE HOMOLOG AND ITS GATING-RELATED STRUCTURAL DYNAMICS IN MEMBRANE-MIMETICS. Rupasree Brahma, H Raghuraman 1467-Pos Board B420 COMPARING PROTON TRANSFER PATHWAYS IN PSII FROM CYANOBAC TERIA AND HIGHER PLANTS USING MONTE CARLO SAMPLING TO TRACE HYDROGEN BOND NETWORKS. Jose C. Ortiz-Soto , Benjamin Roman jenko, Carmela Guadagno, Divya Matta, Marilyn Gunner

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